A5015000429- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- Meat and Animal Product Quality
- Reproductive Physiology in Livestock
- Ruminant Nutrition and Digestive Physiology
- Aquaculture Nutrition and Growth
- Animal Genetics and Reproduction
- Livestock Farming and Management
- Natural Products and Biological Research
- Effects of Environmental Stressors on Livestock
- Nutrition, Genetics, and Disease
- Genomic variations and chromosomal abnormalities
- Livestock Management and Performance Improvement
- Peroxisome Proliferator-Activated Receptors
- Molecular Biology Techniques and Applications
- melanin and skin pigmentation
- Metabolism and Genetic Disorders
- Animal Disease Management and Epidemiology
- Animal Nutrition and Physiology
- Chromosomal and Genetic Variations
- Genetics and Plant Breeding
- T-cell and Retrovirus Studies
Universidade Federal da Bahia
2021-2025
Universidade Estadual Paulista (Unesp)
2014-2021
University of Guelph
2019
Núcleo de Pesquisas Aplicadas (Brazil)
2016
The objective of this study was to identify genomic regions that are associated with meat quality traits in the Nellore breed. steers were finished feedlots and slaughtered at a commercial slaughterhouse. This analysis included 1,822 phenotypic records tenderness 1,873 marbling records. After control, 1,630 animals genotyped for tenderness, 1,633 marbling, 369,722 SNPs remained. results reported as proportion variance explained by windows 150 adjacent SNPs. Only largest effects considered....
Saturated fatty acids can be detrimental to human health and have received considerable attention in recent years. Several studies using taurine breeds showed the existence of genetic variability thus possibility improvement acid profile beef. This study identified regions genome associated with saturated, mono- polyunsaturated acids, n-6 n-3 ratios Longissimus thoracis Nellore finished feedlot, single-step method. The results that 115 windows explain more than 1 % additive variance for 22...
Fatty acid type in beef can be detrimental to human health and has received considerable attention recent years. The aim of this study was identify differentially expressed genes longissimus thoracis muscle 48 Nellore young bulls with extreme phenotypes for fatty composition intramuscular fat by RNA-seq technique. Differential expression analyses between animals phenotype showed a total 13 myristic (C14:0), 35 palmitic (C16:0), 187 stearic (C18:0), 371 oleic (C18:1, cis-9), 24 conjugated...
The aim of this study was to assess genome-wide autozygosity in a Nellore cattle population and characterize ROH patterns islands that may have occurred due selection within its lineages. It attempts also compare estimates inbreeding calculated from (FROH), genomic relationship matrix (FGRM), pedigree-based coefficient (FPED).The average number per animal 55.15 ± 13.01 with an size 3.24 Mb. genome is composed mostly by high shorter segments accounting for 78% all ROH, although the proportion...
The buffalo population raised in Brazil tend to show loss of genetic variability over generations, with significant estimates inbreeding depression. Besides mating genetically distant individuals, other tools can be used maintain/increase the population, such as use PRDM9 genotypes. gene promotes creation crossing-over points across genome, each allele promoting a different hotspot. Thus, increasing frequency less frequent alleles allows emergence new haplotypes and increases variability....
Carcass traits measured after slaughter are economically relevant in beef cattle. In general, the house payment system is based on HCW. Ribeye area (REA) associated with amount of meat carcass, and a minimum backfat thickness (BFT) necessary to protect carcass during cooling. The aim this study was identify potential genomic regions harboring candidate genes affecting those Nellore data set used present consisted 1,756 males phenotype records. A subset 1,604 animals had both genotypic...
The objective of this study was to determine whether visual scores used as selection criteria in Nellore breeding programs are effective indicators carcass traits measured after slaughter. Additionally, evaluated the effect different structures relationship matrix ( and ) on estimation genetic parameters prediction accuracy values. There were 13,524 animals for conformation (CS), finishing precocity (FP), muscling (MS) 1,753, 1,747, 1,564 LM area (LMA), backfat thickness (BF), HCW,...
Traditional single nucleotide polymorphism (SNP) genome-wide association analysis (GWAA) can be inefficient because SNPs provide limited genetic information about genomic regions. On the other hand, using haplotypes in statistical may increase extent of linkage disequilibrium (LD) between and causal variants also potentially capture epistastic interactions within a haplotyped locus, providing an power robustness studies. We performed GWAA (413,355 SNP markers) based on variable-sized sliding...
The objective of this study was to identify associations between known polymorphisms in genes related adipose tissue and sexual precocity Nellore cattle.A total 1689 precocious nonprecocious heifers belonging farms participating Conexão Delta G breeding program were studied.SNPs from the Illumina High-Density Bovine SNP BeadChip used.This chip contains 777,000 SNPs located within region candidate at a distance up 5 kb, considering that linkage disequilibrium (LD) exists distance.Linear...
Reproductive traits are of the utmost importance for any livestock farming, but difficult to measure and interpret since they influenced by various factors. The objective this study was detect associations between known polymorphisms in candidate genes related sexual precocity Nellore heifers, which could be used breeding programs. Records 1,689 precocious non-precocious heifers from farms participating Conexão Delta G program were analyzed. A subset single nucleotide (SNP) located region at...
The objective of this study was to quantify the magnitude genotype-environment interaction (GxE) effects on age at first calving (AFC), scrotal circumference (SC), and yearling weight (YW) in Nellore cattle using reaction norms. For study, 89,152 records female male animals obtained were used. Genetic parameters estimated with a single-trait random-regression model Legendre polynomials as base functions. heritability estimates low medium for AFC (0.05 0.47) high SC (0.32 0.51) YW (0.13...
The objective of this work was to estimate the allele polymorphism frequencies genes in Nellore cattle and associate them with meat quality carcass traits. Six hundred males were genotyped for following polymorphisms: DGAT1 (VNTR 18 nucleotides at promoter region); ANK1, a new polymorphism, identified mapped here gene regulatory region NW_001494427.3; TCAP (AY428575.1:g.346G>A); MYOG (NW_001501985:g.511G>C). In association study, phenotype data hot weight, ribeye area, backfat...
chromosomes 2 and 6 for LEA on 7, 1, BF.For HCW, associations with SNPs were found 13, 14, 28, in addition to genome regions that directly related this trait, such as the EFCAB8 VSTM2L genes, bone development (RHOU).Some located very close proximity genes involved basal metabolism (BLCAP, NNAT, CTNNBL1, TGM2, LOC100296770) immune system (BPI).
The objective of this study was to investigate the application BLUP and single step genomic (ssGBLUP) models in different scenarios paternity uncertainty with strategies scaling G matrix match A22 matrix, using simulated data for beef cattle. Genotypes, pedigree, phenotypes age at first calving (AFC) weight 550 days (W550) were heritabilities based on real (0.12 AFC 0.34 W550). Paternity 0, 25, 50, 75, 100% multiple sires (MS) studied. genome had a total length 2,333 cM, containing 735,293...
The aim of the present study was to estimate covariance components and genetic parameters for beef fatty acid (FA) composition intramuscular fat in longissimus thoracis muscle Nelore bulls finished feedlot. Twenty-two FAs were selected. heritability estimates individual ranged from 0.01 0.35. myristic (0.25 ± 0.09), palmitic (0.18 0.07), oleic (0.28 linoleic (0.16 0.06) α-linolenic (0.35 0.10) moderate. Stearic, elaidic, palmitoleic, vaccenic, conjugated acid, docosahexanoic, eicosatrienoic...
Indicine cattle breeds are adapted to the tropical climate, and their coat plays an important role in this process. Coat color influences thermoregulation adhesion of ectoparasites may be associated with productive reproductive traits. Furthermore, is used for breed qualification, breeders preferring certain colors. The Gir characterized by a wide variety Therefore, we performed genome-wide association studies identify candidate genes cattle. Different phenotype scenarios were considered...
Abstract The aim of this study was to evaluate the genomic predictions using single‐step best linear unbiased predictor (ssGBLUP) method based on SNPs and haplotype markers associated with beef fatty acids (FAs) profile in Nelore cattle. data set contained records from 963 bulls finished feedlot (±90 days) slaughtered approximately 24 months age. Meat samples Longissimus dorsi muscle were taken for FAs measurement. quantified by gas chromatography a SP‐2560 capillary column. Animals...