Cyclic Vomiting Syndrome (CVS) is a disorder characterized by recurrent, stereotypic episodes of incapacitating nausea, vomiting and other symptoms, separated intervals comparative wellness. This report describes the clinical features, co-morbidities problems encountered in management 41 adult patients who met diagnostic criteria for CVS.This retrospective study adults with CVS seen between 1994 2003. Follow-up data were obtained mailed questionnaires.Age onset ranged from 2 to 49 years. The...

Mitochondrial dysfunction is a hypothesized component in the multifactorial pathogenesis of migraine without aura (MoA, 'common migraine') and related condition cyclic vomiting syndrome (CVS). In this study, entire mitochondrial genome was sequenced 20 haplogroup-H CVS patients, subject group studied because greater genotypic phenotypic homogeneity. Sequences were compared against controls. Polymorphisms interest tested 10 additional subjects 112 adults with MoA. The 16519C-->T polymorphism...

Cyclic vomiting syndrome (CVS), which is defined by recurrent stereotypical episodes of nausea and vomiting, a relatively-common disabling condition that associated with migraine headache mitochondrial dysfunction. Co-enzyme Q10 (Co-Q) nutritional supplement has demonstrated efficacy in pediatric adult migraine. It increasingly used CVS despite the complete lack studies to demonstrate its value treatment Using an Internet-based survey filled out subjects or their parents, efficacy,...

Migraine headache is a very common condition affecting about 10% of the population that results in substantial morbidity and economic loss. The two most variants are migraine with (MA) without (MO) aura. Often considered to be migraine-like variant, cyclic vomiting syndrome (CVS) predominately childhood characterized by severe, discrete episodes nausea, vomiting, lethargy. Disease-associated mitochondrial DNA (mtDNA) sequence suggested CVS based upon strong bias towards maternal inheritance...

Cyclic vomiting syndrome (CVS), characterized by severe discrete episodes of nausea, vomiting, and lethargy, is a fairly common, disabling, predominately-childhood condition most often associated with migraine dysautonomic features. Our group recently reported that children CVS additional neuromuscular disease manifestations demonstrate strong maternal inheritance multiple abnormal urine organic acids, suggesting the presence predisposing mitochondrial DNA (mtDNA) sequence variants. In order...

Cyclic vomiting syndrome (CVS), a chronic disorder characterized by recurrent episodes of vomiting, is frequently unrecognized and associated with high utilization emergency department (ED) services.A web-based survey was posted on the Vomiting Syndrome Association (CVSA) website to assess ED services in patients CVS.Of 251 respondents, 104 (41.4%) were adult CVS 147 (58.6%) caregivers pediatric patients. In group, median number visits for symptoms 15(range 1 - 200), 7 prior diagnosis (range...

Abstract Background Cyclic vomiting syndrome (CVS) is a disorder recognized for its unique intensity of attacks and inordinate impact on quality life. There considerable symptom overlap with migraine. Due to the lack evidence‐based treatment algorithms, current management strategies vary. Objective These guidelines were formulated replace prior expert consensus recommendations assist patients clinicians in pediatric CVS. Methods Guidelines developed by multidisciplinary panel experts patient...

Abstract Cyclic vomiting syndrome (CVS), characterized by severe discrete episodes of nausea, vomiting, and lethargy, is a predominately childhood condition associated with migraine dysautonomic features. Disease‐associated mitochondrial DNA (mtDNA) sequence variants are suggested strong maternal bias in the inheritance migraine, recent findings mtDNA few children CVS additional neuromuscular disease manifestations (“CVS+”). A clinical interview using questionnaire was administered...

Cyclic vomiting syndrome, which is characterized by severe discrete episodes of nausea, vomiting, and lethargy, a fairly common, disabling, predominately childhood condition. Approximately 25% cases have coexisting neuromuscular disease manifestations (cyclic syndrome plus). To determine whether patients with cyclic represent distinct subentity within clinical interview was conducted regarding 80 randomly ascertained sufferers from association database. plus “cyclic minus,” herein defined as...

Declines in prenatal smoking rates have changed the composition of maternal smokers while public policy during 1990s has likely made it more difficult to reach them. Medicaid expansions 1980s/early insured women some time pregnancy, but 1996 welfare reform unexpectedly reduced enrollment by eligible pregnant women; overall, insurance coverage declined since 2000. As sector struggles with fewer resources, is important understand sociodemographic characteristics smokers, their patterns care,...

Abstract Objective To develop and test a parsimonious actionable model of effective technology use (ETU). Design Cross-sectional survey primary care providers (n = 53) in large integrated health organization that recently implemented new medication reconciliation technology. Methods Surveys assessed 5 technology-related perceptions (compatibility with work values, implementation climate, compatibility processes, perceived usefulness, ease use) 1 outcome variable, ETU. ETU was measured as...

Although medication reconciliation (MR) can reduce discrepancies, it is challenging to operationalise. Consequently, we developed a health information technology (HIT) collect patient history and make available the primary care (PC) provider. We deployed self-service kiosk in PC clinic that permits patients indicate adherence history. Patient responses are immediately viewable legacy electronic record. This paper describes survey assess provider perceptions of our HIT implementation...

Our objectives were to (1) develop an in-depth understanding of the workflow and information flow in medication reconciliation, (2) design reconciliation support technology using a combination rapid-cycle prototyping human-centered design.Although is national patient safety goal, limitations both physical environment can make it challenging implement durable systems. We used several human factors techniques gather requirements new process collect history at hospital admission.We completed...

Background The Veterans Affairs Portland Healthcare System developed a medication history collection software that displays prescription names and images. Objective This article measures the frequency of discrepancy reporting using compares with paper-based process. also determines accuracy each method by comparing both strategies to best possible history. Study Design Randomized, controlled, single-blind trial. Setting Three community-based primary care clinics associated System: 300-bed...

Abstract Research has shown that aberrant behaviors of people with developmental disabilities have multiple determinants; these, medical problems and their potential relations to behaviors, been, for the most part, not studied. This retrospective study examined 26 acute treatements 10 elderly disabilities. Results showed 73.1% decreased in frequency after treatments. The suggests importance treatments as possible factors occurrence this population.

Medication-prescribing errors generated at interfaces-in-care are the most common cause of preventable health care and contribute substantially to adverse patient outcomes. For this reason, standardized medication reconciliation (MR) processes need be inserted these interfaces. However, MR is an inherently complex task, little data exist inform system-based operationalization. The Portland Informatics Center addressed challenge by creating electronic patient-directed multimedia survey...