- Venous Thromboembolism Diagnosis and Management
- Tuberculosis Research and Epidemiology
- Acute Ischemic Stroke Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Blood properties and coagulation
- Tracheal and airway disorders
- Parasitic infections in humans and animals
- Medical Imaging and Pathology Studies
- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Studies on Chitinases and Chitosanases
- Respiratory and Cough-Related Research
- Hematological disorders and diagnostics
- Dermatological and COVID-19 studies
- Congenital Diaphragmatic Hernia Studies
- Pulmonary Hypertension Research and Treatments
- Parasites and Host Interactions
- Mycobacterium research and diagnosis
- Parasitic Infections and Diagnostics
- Atrial Fibrillation Management and Outcomes
- COVID-19 Clinical Research Studies
- Obstructive Sleep Apnea Research
- Occupational exposure and asthma
- Herpesvirus Infections and Treatments
- Pneumonia and Respiratory Infections
Memorial Ankara Hospital
2021
Altınbaş University
2020
Sağlık Bilimleri Üniversitesi
2019
Recep Tayyip Erdoğan University
2013-2017
Ondokuz Mayıs University
2012-2015
Ankara Atatürk Göğüs Hastalıkları Ve Göğüs Cerrahisi Eğitim Ve Araştırma Hastanesi
2011-2014
Istanbul 29 Mayis University
2014
<h3>BACKGROUND:</h3> Patients with COPD face an increased risk of cardiovascular disease and cardiac mortality. Carotid femoral pulse wave velocity (cf-PWV) is a validated measure arterial stiffness, well recognized predictor adverse outcomes, offers higher predictive value than classical factors. We investigated the association between stiffness using cf-PWV as noninvasive technique. <h3>METHODS:</h3> This clinical study was prospective, observational, cross-sectional. Sixty-two subjects...
Pulmonary fibrosis is a rare and progressive lung disease with high mortality rate. The treatment regimens still fail to recover the disease. Leflunomide (LEF) an immunomodulatory agent antiproliferative activity that used for of rheumatoid arthritis. purpose study investigate potential therapeutic efficacy LEF in bleomycin (BLM) induced pulmonary fibrosis.A total 21 male, adult wistar albino rats were used. animals divided into three groups as control, BLM plus (n=7). In group, mice treated...
An early prediction of prognosis in pulmonary embolism (PE) is a crucial clinical entity. The aim the study to investigate whether growth differentiation factor-15 (GDF-15) or N-terminal pro-brain natriuretic peptide levels (NT-proBNP) can better predict 30 day overall mortality patients with normotensive acute PE.Patients high probability PE, low/intermediate and positive D-dimer test, underwent contrast-enhanced computed tomography ventilation/perfusion lung scan. Simplified severity...
The association between mortality and localization of central thrombus in hemodynamically stable patients with pulmonary embolism (PE) is unclear. Sufficient data are not available to help clinicians select low molecular weight heparin (LMWH), unfractionated (UFH) thrombolytics for the management thrombus. present study aims investigate whether artery affects 30-day rate, compare outcomes different treatment approaches thrombus.This multi-central, prospective, observational included 874 PE...
Copeptin which is the C-terminal fragment of antidiuretic hormone (ADH), a biomarker that has been reported to be increased in various cardiovascular disorders, cerebrovascular diseases and associated with prognosis. Patients obstructive sleep apnea syndrome (OSAS) have tendency develop coronary cerebral atherosclerotic diseases.The aim present study was copeptin levels patients control group order determine whether could used as predicting severity OSAS possible complications this group.A...
This cross-sectional study was conducted in a foundry factory to assess the prevalence of respiratory symptoms and occupational asthma workers. Physical examination, spirometric evaluation, chest radiograph, questionnaire related were performed. Monitoring peak expiratory flow rates, reversibility test, high-resolution computed tomographies performed for participants having and/or impaired function test. A total 347 including 286 workers from production department 61 subjects who worked...
Inadequate serum levels of antimycobacterial drugs have been associated with treatment failure, relapse and acquired drug resistance as well high concentrations these may cause intolerance toxic effects. We objected in this study to determine anti-tuberculosis know the determinants their concentrations. Venous blood samples was obtained 2 6 h after ingestion, were analysed using performance liquid chromatography. Among 49 enrolled active pulmonary tuberculosis patients, the prevalances...
Genetic and acquired thrombophilic risk factors may play role on developing venous thromboembolism (VTE). In many cases of pulmonary (PE) it can not be defined any explicit factor. this study we aimed to identify the plasma viscosity level PE. The investigation was planned prospectively 33 patients with PE 36 apparently healthy nonsmoker volunteers as control group were enrolled in study. mean levels determined 1.42±0.30 cP 1.29±0.22 respectively. found different between (p=0.009)....
Chronic obstructive pulmonary disease (COPD) is a major health problem with increasing morbidity and mortality throughout the world. YKL-40 chitin-binding glycoprotein consisting of 383 amino acids, molecular mass 40 kDa, its serum level elevated in inflammatory diseases. newly recognized biomarker inflammation has not been thoroughly investigated COPD. The aim study to investigate relationship between levels severity population consisted 52 patients COPD mean age 60.2 ± 10.1 years....
The cigarette smoking and the obesity are main reasons of mortality morbidity. There limited studies detecting relationship between obesity. However reported results contradictory. aim study is to investigate effects on body mass index A total 983 patients consisting 464 (47%) male 519 (53%) female who admitted department chest disease outpatient clinic were enrolled in this study. age, gender, (BMI), diastolic systolic blood pressure levels states recorded. mean age was 50.7±14.8 years...
ÖZET Amaç: Sestodlardan Echinococcosis granulosus'un metasestod formunun neden olduğu bir hastalık olan kist hidatik, karaciğerden sonra ikincil sıklıkta akciğerlerde görülmektedir.Perfore olup bronşa veya plevraya açılan kist, komplikasyonlara olabilir.Bu çalışmanın amacı, akciğer hidatik hastalığının ve komplikasyonlarının klinik özelliklerini sıklığını araştırmaktır
Cerebral fat embolism syndrome is a lethal complication of long-bone fractures and clinically manifasted with respiratory distress, altered mental status, petechial rash.We presented 20-year-old male admitted gun-shot wounds to his left leg.Twenty-four hours after the event, he had generalized tonic clonic seizures, decorticate posture Glascow Coma Scale seven localization painful stimuli.Subsequent magnetic resonance imaging brain showed star-fi eld pattern defi ning multiple lesions...
Recent evidence suggests that YKL-40 is a relatively new biomarker of inflammation and it involved in the pathogenesis several pulmonary diseases. Details serum pleural effusions however, remain unknown. We aimed to assess whether an accurate effusions.This clinical study was prospective, observational cross-sectional. The concentrations fluid conventional marker levels were measured 80 subjects with effusions, including 23 transudates caused by congestive heart failure (CHF), 57 exudates...
Background and objectives: Despite advances in treatment modalities, the discovery of optimal medical therapies still remains a necessity management pulmonary fi brosis. Material methods:The experiments were performed 35 adult Sprague Dawley rats, randomly allotted into one ve groups (n=7).The control group was treated with 1 ml/kg, 0.9 % saline; BLM given single dose (2.5 U/kg); BLM+ER ER (10 mg/kg/day po) for 14 days after administration; BLM+SMT i.p injections SMT (20 mg/kg/ day)...
Pulmonary sequestration is an embryonic, cystic lung tissue that supplied by systemic blood circulation. It a nonfunctional parenchyma unconnected to normal tracheobronchial system. In cases of pulmonary sequestration, surgical interventions should be performed in order prevent possible complications such as massive hemoptysis and infections. Preoperative imaging treatment planning done carefully. We present uncommon case recurrent caused intralobar located the left lower lobe.
Lung cancers rarely metastasize to intracardiac ventricular wall and subsequently embolizes systemic circulation, causing arterial occlusion.The current study reports a case of lung cancer with peripheral embolism.This is unique report because the first diagnostic tool bronchogenic carcinoma was embolectomy material during hospitalization initial evaluation stage patient.Tumor embolization should be considered in differential diagnosis an abrupt cessation circulation.
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Giant pulmonary hydatid cyst is usually encountered in adolescents and children who are older than 10 years. A relatively higher elasticity of the lung tissue allows rapid growth cysts. We present a case 15-year-old male was admitted with complaint frequent persistent dry cough for over month. Computed tomographic scan revealed giant thick enhancing rim an "air bubble" sign. Diagnosis confirmed by surgery histopathological examination.
The aim of the study was to evaluate automated mycobacteria growth A±ndicator tube (MGIT) for drug susceptibility testing of Mycobacterium tuberculosis and determine resistance patterns. We used BACTEC MGIT 960 System of M. tuberculosis complex isolates major anti tuberculous agents. Patients with single and first positive were enrolled in study. have performed our between January 2005 December 2010 monitoring patterns six years. A total 1240 (77.16%) 1607 susceptible all four...