A5033613799- Poisoning and overdose treatments
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Nitric Oxide and Endothelin Effects
- Cardiac Arrest and Resuscitation
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurological Disorders and Treatments
- Eicosanoids and Hypertension Pharmacology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Liver Disease Diagnosis and Treatment
- Cardiovascular Issues in Pregnancy
- Mechanisms of cancer metastasis
- Trauma Management and Diagnosis
- Heme Oxygenase-1 and Carbon Monoxide
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Burn Injury Management and Outcomes
- Migraine and Headache Studies
- Folate and B Vitamins Research
- Salivary Gland Disorders and Functions
- Pneumonia and Respiratory Infections
- Cardiovascular Disease and Adiposity
- Cancer Mechanisms and Therapy
- Liver Disease and Transplantation
Ondokuz Mayıs University
2012-2021
Bezmiâlem Vakıf Üniversitesi
2021
Hacettepe University
2009-2018
Objectives. We aimed to explore whether the use of methylphenidate relates leptin, ghrelin, adiponectin, and brain-derived neurotrophic factor (BDNF). In addition, relationship between methylphenidate-related weight loss in attention deficit hyperactivity disorder (ADHD) patients these biomolecules were evaluated. Methods. Thirty ADHD receiving 20 healthy controls included. Leptin, BDNF levels measured at baseline after two-month treatment both groups. Results. At baseline, similar control...
N-myc downstream-regulated gene 1 (NDRG1) is defined as metastasis suppressor and can be downregulated in many types of cancers, reported to an indication tumor progression hepatocellular carcinomas. Several in-vivo in-vitro studies
The main purpose of this study was to assess the role S100B protein, neuron-specific enolase (NSE), and glial fibrillary acidic protein (GFAP) in evaluation hypoxic brain injury acute carbon monoxide (CO)-poisoned patients. This cross-sectional conducted among patients with CO poisoning who referred emergency department a 1-year period. Serum levels NSE, GFAP were determined on admission. A total 55 CO-poisoned (mean age ± standard deviation, 45 20.3 years; 60% women) included study. control...
The aim of this study was to investigate the relationship between pulmonary thromboembolism (PTE) and serum endocan levels. included 46 patients with a diagnosis PTE control group (25 healthy individuals). Serum levels in all participants' blood samples were measured. average age individuals 61.76 ± 16.39 years. There significant difference those [321.93 ng/l (111.35-2511.33) 192.77 (118.30-309.02), respectively; P < 0.030]. submassive [469.41 (258.13-800.54)] massive groups [719.18...
Background and Objective Smoking is an important risk factor for periodontal disease effects the pathogenesis of disease. This study evaluated impact smoking on gingival crevicular fluid interleukin‐8 ( IL ‐8) lipoxin A 4 (LxA ) levels in patients with without Material Methods total 122 participants were grouped as follows: smokers generalized aggressive periodontitis S‐GAgP, n = 15); chronic S‐CP, 17); gingivitis SG, classified periodontally healthy SH, nonsmokers (N‐ GAgP, CP, (NG, (NH,...
Our purpose in this study was to analyze telomere length and telomerase activity before after eradication treatment gastric mucosa patients positive for H. pylori.There were two groups: a control group (n=17) (n=21). For pylori eradication, the administrated proton pump inhibitor (PPI) + clarithromycin amoxicillin or PPI metronidazole tetracycline bismuth 14 days. Telomere analyzed with RT-PCR PCR-ELISA on biopsy specimens from antrum. The result p<0.05 considered significant.Prior there no...
Objectives Pro-inflammatory mediators are thought to play both peripheral and central roles in migraine pathophysiology. Prostaglandins leukotrienes, known as the eicosanoids, degradation products of arachidonic acid constitute signalization components inflammatory pathways. This study was designed assess concentrations leukotriene E4 (LT-E4) prostaglandin F2a (PG-F2a) children with migraine. Materials Methods involved patients aged ≤18 years who presented Ondokuz Mayis University Children's...
The Pringle maneuver is used in hepatic surgery to prevent blood loss but associated with ischemia- reperfusion injury. To investigate the effect of infliximab on inflammation and apoptosis rat intestinal mucosa during ischemia-reperfusion (IR) A total 30 male Wistar albino rats were equally divided into three groups be subjected (i) sham operation (sham), (ii) IR injury via (pringle) or (iii) (IFX) group (IFX was given at a dose 3 mg/kg for days before injury). Following period 60 min.,...
Surfactant protein D (SP-D) is a biomarker specific to the lungs. Our aim was investigate relationship between clinical probability scores and serum levels of SP-D indicate severity lung injury that develops secondary hypoxia in pulmonary embolism (PE).We included three groups study: non-massive PE (n = 20), sub-massive control group which consisted healthy volunteers. The modified Geneva Wells scoring systems were performed for PE, patients classified as low risk, moderate high risk....
To evaluate the predictive powers of serum surfactant protein D (SP-D) levels as a biomarker lung damage in tuberculosis and diseases.This study prospectively included 137 subjects who applied to our hospital. We measured SP-D from patients with active (TB) (n = 35), chronic obstructive disease (COPD) experiencing acute exacerbations 30), pneumonia 45), control 27).The mean age all was 54.89 +/- 18.81 years (15 100 years); males accounted for two-thirds (70.1%) cases. Serum were higher...
Ouabain is a cardiotonic steroid and specific inhibitor of the Na(+)/K(+)-ATPase. The relationship between ouabain treatment unfolded protein response (UPR) in cells not precisely understood. Therefore, we studied possible effects on proliferation, apoptosis, UPR. HepG2 were cultured overnight then treated with various concentrations (0.75 to 750 nM) absence or presence 10 mM 2-deoxyglucose (2-DG) for 48 hours. We also used real-time polymerase chain reaction obtain quantitative measurements...
Aspiration is a serious complication of gastrointestinal (GI) decontamination procedure. Studies have shown that tumor necrosis factor-α (TNF-α) blockers beneficial effects on lung injury. Therefore, the authors investigated attenuation by infliximab (INF) activated charcoal (AC)- and polyethylene glycol (PEG)-induced injury in rat model. Forty-two male Sprague-Dawley rats were allotted into 1 6 groups: saline (NS), (AC), (PEG), NS+INF treated, AC+INF PEG+INF treated. All materials aspirated...
The study attempts to investigate the effect of acute aerobic and anaerobic exercise on blood parameters determine whether change between exercise. To achieve objectives this study, 25 male athletes participated in research. Aerobic (Shuttle run test) (Running aerobic) Sprint test (RAST) were applied subjects with a one-week interval. Before (resting), 1 minute 60 minutes after both exercises' protocol, subjects' samples taken hematologic values. A rise values was observed exercise, but it...
Crimean-Congo Hemorrhagic Fever (CCHF) is a life threatening acute viral infection characterized by fever, bleeding, leukopenia and thrombocytopenia. It major emerging infectious diseases threat, but its pathogenesis remains poorly understood few data exist for the role of apoptosis in infection. We aimed to assess apoptotic gene expression leukocytes cross-sectional cohort study adults with CCHF. Twenty participants CCHF 10 healthy controls were recruited at tertiary unit Turkey; admission...
Pre-eclampsia is a syndrome characterized by hypertension and proteinuria. The aim of this study was to investigate neopterin concentrations in cord blood maternal serum patients with pre-eclampsia control group.Cord were measured 21 27 subjects. Neopterin high performance liquid chromatography.Cord significantly increased compared controls (54.3+/-16.8 vs. 43.4+/-8.5 nmol/L, p=0.011, respectively). Maternal (257.3+/-36.8 150.9+/-33.8 p<0.001) also higher pre-eclampsia.Cord are...
Preeclampsia is a syndrome characterized by hypertension and proteinuria. The aim of this study to find the relationship between preeclampsia, asymmetric dimethyl arginine (ADMA), oxidant/antioxidant system. Twenty-one preeclamptic 28 normal pregnant women were included in study. In cord bloods, ADMA parameters measured. Asymmetric levels significantly increased pregnancies compared control group (p = 0.006). activities antioxidant enzymes malondialdehyde < 0.001, p 0.022, respectively)....