- Spine and Intervertebral Disc Pathology
- Neurological Disease Mechanisms and Treatments
- Spinal Fractures and Fixation Techniques
- Spinal Hematomas and Complications
- Cervical and Thoracic Myelopathy
- Biochemical effects in animals
- Medical Imaging and Analysis
- Phytochemistry and biological activity of medicinal plants
- Bone and Joint Diseases
- Infectious Diseases and Tuberculosis
- Brain Metastases and Treatment
- Cardiac Ischemia and Reperfusion
- Spinal Cord Injury Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Spondyloarthritis Studies and Treatments
- Neurological Disorders and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Phytoestrogen effects and research
- Curcumin's Biomedical Applications
- Hedgehog Signaling Pathway Studies
- Fatty Acid Research and Health
- Bone Tumor Diagnosis and Treatments
- Surgical Sutures and Adhesives
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Surgical Oncology
Çanakkale Onsekiz Mart Üniversitesi
2014-2024
Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi
2020
Canakkale Onsekiz Mart Universitesi Tip Fakultesi Hastanesi
2014-2015
Ege Üniversitesi Tıp Fakültesi Hastanesi
2011
Kocaeli Üniversitesi
2007
St. Luke's Hospital
1964
Texas Health Dallas
1964
United States Department of Veterans Affairs
1964
Background In recent years, white blood cells (WBCs) and their subtypes have been studied in relation to inflammation. The aim of our study was assess the relationship between neutrophil–lymphocyte ratio (NLR) ankylosing spondylitis (AS). Materials methods We enrolled a total 177 patients, 96 AS 81 healthy controls. Complete count, WBC, neutrophil lymphocyte levels were measured, NLR calculated. assessment AS, we used erythrocyte sedimentation rate, C‐reactive protein (CRP), Bath Ankylosing...
Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that daidzein exhibits neuroprotective effects on cerebral ischemia. Rat models of middle artery occlusion were intraperitoneally administered daidzein. Biochemical and immunohistochemical tests showed superoxide dismutase nuclear respiratory factor 1 expression levels the brain tissue decreased after ischemia they increased obviously administration; malondialdehyde level apoptosis-related cysteine...
Brain ischemia and treatment are important topics in neurological science. Free oxygen radicals inflammation formed after accepted as the most significant causes of damage. Currently there studies on many chemopreventive agents to prevent cerebral Our aim is research preventive effect active ingredient syringic acid, previously unstudied, oxidative damage ischemia.The rats were randomly divided into 4 groups: control group (no medication or surgical procedure), sham (artery occlusion),...
Objective: Many cancer patients treated with radiotherapy suffer severe side effects during and after their treatment. The aim of this study was to investigate the irradiation addition Nigella sativa oil (NSO) on oxidant/antioxidant system in liver tissue irradiated rats. Methods: A total 24 Sprague-Dawley rats were randomly distributed into three groups equal numbers. control group received neither NSO nor but 1-ml saline orally. (IR) head 5 gray (Gy) gamma as a single dose, plus IR both Gy...
increases the synthesis of some proinflammatory gene products (leucocyte adhesion molecule, cytokines, etc.) and bioactive compounds (endothelin-1, thromboxane A2, in endothelial cells while it suppresses expression cyto-protective genes their enzyme including nitric oxide (NO) prostacyclins (5).At this critical stage, reperfusion-the restoration blood flow following ischemia-must be accomplished order to prevent irreversible tissue/organ damage.It ihas been proven that temporary occlusion...
There are few studies on the neuroprotective effects of syringaldehyde in a rat model cerebral ischemia. The study aimed to elucidate mechanisms underlying ischemic brain cells. Rat models ischemia were intraperitoneally administered syringaldehyde. At 6 and 24 hours after administration, cell damage rats was obviously reduced, superoxide dismutase activity nuclear respiratory factor 1 expression tissue markedly increased, malondiadehyde level decreased, apoptosis-related cysteine peptidase...
The purpose of this study was to evaluate the possible protective/therapeutic effects aloe vera (AV) on ischemia-reperfusion injury (I/R) spinal cord in rats.A total 28 Wistar Albino rats were divided into four random groups equal number (n = 7). Group I (control) had no medication or surgery; II underwent ischemia and given medication; III administered AV by gastric gavage for 30 days as pre-treatment; IV single dose intraperitoneal methylprednisolone (MP) after ischemia. Nuclear...
Spinal cord injury (SCI) can lead to significant cardiac arrhythmia. However, P-wave, QT dispersion, and risk factors in these patients have not been widely investigated. In this study, we assessed whether there is a relationship between electrocardiogram (ECG) parameters SCI patients.The study population consisted of 85 38 control subjects. P-wave durations were measured using 12 leads the surface ECG. dispersion was defined as difference maximum minimum duration. largest smallest interval...
[Purpose] The aim this study was to assess the relation between bone mineral density (BMD) and mean platelet volume (MPV) in ankylosing spondylitis (AS) patients, evaluate diagnostic role of diffusion-weighted magnetic resonance imaging (MRI). [Subjects Methods] Fifty patients diagnosed with AS were divided into two groups on basis BMD, a normal group (n=30) an osteopenic (n=20) group. [Results] Duration disease BMD 10.3±7.0 years, while it 16.7±12.2 years osteopenia MPV high group, no...
PURPOSE: To investigate the neuroprotective effects of Sulindac on hippocampal complex after global cerebral ischemia/reperfusion (I/R) injury in rats. METHODS: Thirty one Sprague-Dawley rats were used, distributed into group I (sham) n:7 used as control. For II (n:8), III (n:8) and IV rats, ischemia was performed via occlusion bilateral internal carotid artery for 45 minutes continued with reperfusion process. 0.3 mL/kg/h 0.9 % sodium chloride infused intraperitoneally to Group before...
Diagnosis, treatment, and surgery for lumbar disc herniations have existed over a century. However, during the last three decades, there been many new developments in imaging techniques, surgical procedures, physical medicine, rehabilitation. In light of this, most effective appropriate treatment is controversial. Spontaneous regression sequestrated, extruded, or protruded herniation has often reported literature, although it still rare phenomenon. After thorough review we did not find any...
The intervertebral disc starts to degenerate when a human being begins stand and learn walk. It is known that many extrinsic, intrinsic genetic factors play role in degeneration. In this study, we examined whether the matrix metalloproteinase 11 might be associated with degeneration.Fifty-six patients lumbar herniations who were operated at Göztepe Education Research Hospital, Neurosurgery Clinic between September 2008 December 2009 prospectively reviewed. History complaints obtained from...
Dural injury during spinal surgery can subsequently give rise to a remote cerebellar hemorrhage (RCH). Although the incidence of such is low, resulting be life threatening. The mechanism underlying formation not known, but it mostly thought develop after venous infarction. Cerebellar mutism (CM) frequent complication posterior fossa operations in children, rarely seen adults. development CM an RCH has been described. We describe case 65-year old female who lost cerebrospinal fluid...