Visually guided movements can be inaccurate, especially if unexpected events occur while the movement is programmed. Often errors of gaze are corrected before external feedback processed. Evidence presented from macaque monkey frontal eye field (FEF), a cortical area that selects visual targets, allocates attention, and programs saccadic movements, for neural mechanism correct saccade afferent or performance monitoring signals register error. Macaques performed search color singleton...

The dynamics of visual selection and saccade preparation by the frontal eye field was investigated in macaque monkeys performing a search-step task combining classic double-step with search. Reward earned for producing to color singleton. On random trials target one distractor swapped locations before were rewarded shifting gaze new singleton location. A race model accounts probabilities latencies saccades initial final provides measure duration covert compensation process—target-step...

In the previous studies on neural control of saccade initiation using countermanding paradigm, movement and visuomovement neurons in frontal eye field were grouped as movement-related neurons. The activity both types was modulated when a inhibited response to stop signal, this modulation occurred early enough contribute initiation. We now report functional difference between these two classes saccades are produced. Movement exhibited progressive accumulation discharge rate following target...

Saccadic averaging that causes subjects' gaze to land between the location of two targets when faced with simultaneously or sequentially presented stimuli has been often used as a probe investigate nature computations transform sensory representations into an oculomotor plan. Since saccadic movements involve at least processing stages-a visual stage selects target and movement prepares response-saccade can either occur due interference in planning. By having human subjects perform versions...

Tourette disorder (TD) is characterized by tics, which are sudden repetitive involuntary movements or vocalizations. Deficits in inhibitory control TD patients remain inconclusive from the traditional method of estimating ability to stop an impending action, requires careful interpretation a metric derived race model. One possible explanation for these inconsistencies that model's assumptions independent and stochastic rise GO STOP process fixed threshold often violated, making classical...

Abstract An inhibitory control is exerted when the context in which a movement has been planned changes abruptly making impending inappropriate. Neurons frontal eye field and superior colliculus steadily increase activity before saccadic movement, but cease rise below threshold an saccade withheld response to unexpected stop‐signal. This type of neural modulation majorly considered as outcome race between preparatory processes ramping up reach decision criterion. alternative model claims...

The pupils reflexively constrict or dilate to regulate the influx of light on retinae. Pupillary reflex (PLR) is susceptible many non-visual cognitive processes including covert orientation attention and planning rapid saccadic eye movement. frontal field (FEF) superior colliculus (SC), which also send projections PLR pathway, are two important areas in primate's brain for saccade attention. reaction time (SRT) rate increase activity movement neurons these inversely correlated. This study...

The pupils of the eyes reflexively constrict in light and dilate dark to optimize retinal illumination. Non-visual cognitive factors, like attention, arousal, decision-making, etc., also influence pupillary response (PLR). During passive viewing, eccentricity a stimulus modulates aperture size driven by spatially weighted corneal flux density (CFD), which is product luminance area stimulus. Whether scope attention influences PLR remains unclear. In this study, we contrasted pupil dynamics...

ABSTRACT In response to variable light intensity, the pupils reflexively constrict or dilate maintain a uniform retinal illumination. The pupillary reflex (PLR) pathway receives projections from two important areas in primates’ brain that plan rapid saccadic eye-movement – frontal eye field (FEF) and superior colliculus (SC). speed with which neurons these increase firing rate threshold determines latency of saccade. Micro-stimulation FEF/SC below this modulates magnitude PLR. Nonetheless,...

ABSTRACT Tourette disorder (TD) is characterized by tics, which are sudden repetitive involuntary movements or vocalizations. Deficits in inhibitory control TD patients remain inconclusive from the traditional method of estimating ability to stop an impending action, requires careful interpretation a parameter derived race model. One possible explanation for these inconsistencies that model’s assumptions often violated. Here, we used pair metrics recent alternative model address why stopping...