- Radiation Effects and Dosimetry
- Folate and B Vitamins Research
- Genomics, phytochemicals, and oxidative stress
- Biochemical Analysis and Sensing Techniques
- Free Radicals and Antioxidants
- Food Quality and Safety Studies
- Phytase and its Applications
- Sirtuins and Resveratrol in Medicine
- Garlic and Onion Studies
- Insect Pest Control Strategies
- Biotin and Related Studies
- Fluoride Effects and Removal
- Phytochemicals and Antioxidant Activities
- Weed Control and Herbicide Applications
- Metabolism, Diabetes, and Cancer
- Tea Polyphenols and Effects
- Listeria monocytogenes in Food Safety
- Electrochemical sensors and biosensors
- Enterobacteriaceae and Cronobacter Research
- Diabetes and associated disorders
- Microbial Inactivation Methods
- Amino Acid Enzymes and Metabolism
- Coffee research and impacts
- Biochemical and biochemical processes
- Molecular Sensors and Ion Detection
Université de Strasbourg
2011-2022
Centre National de la Recherche Scientifique
2012-2022
Institut Pluridisciplinaire Hubert Curien
2011-2019
Institut de génétique et de biologie moléculaire et cellulaire
2012-2015
Laboratoire de Chimie
2001-2005
Laboratoire d’Analyse et de Mathématiques Appliquées
2001-2005
A new analytical method (liquid chromatography−antioxidant, LC-AOx) was used that is intended to separate beer polyphenols and determine the potential antioxidant activity of these constituents after they were allowed react online with a buffered solution radical cation 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+). Using LC-AOx method, it possible demonstrate extent very much dependent on phenolic compound considered. The also applied analysis extracts evaluation their at...
Growing evidence supports a link between fatty acid metabolism and amyotrophic lateral sclerosis (ALS). Here we determined the composition of blood lipids to identify markers disease progression survival. We enrolled 117 patients from two clinical centers 48 these were age gender matched with healthy volunteers. extracted total serum cells, separated methyl esters by gas chromatography. measured circulating biochemical parameters indicative metabolic status. Association readouts was studied,...
This study attempts to examine the folic acid stability after irradiation treatment, under different physical states, pH values, and atmosphere conditions. Aqueous samples, in powder, wheat flour fortified with were irradiated by an electron beam (E-beam) between 0 (control) 10.0 kGy. It was realized that state of plays important role on its toward E-beam processing, being largely unstable solution, no matter conditions assayed. Otherwise, powder showed huge stability, even when mixed a dry...
The largely adopted reversed‐phase HPLC analysis of the molecular species isothiocyanates ( ITC s) was performed and showed losses during chromatographic run with eight s. These losses, which obviously impact accuracy quantitative determinations, were due to precipitation in system. At 22° C , they ranged from 5.4% for sulforaphane SFN ) 11.0% benzyl‐ when s injected at 80 μg mL −1 but up three times higher 1 mg reaching 31.9% . water solubility a key determinant extent measured loss. When...
Folates compounds are a B group vitamin vital for important biochemical processes like DNA synthesis and repair in certain biological reactions as cofactor. Folic acid (FA) is composed of pteridine ring, p-aminobenzoic glutamate moieties. Separately, the three moieties have no activity. Folate deficiency can lead to increased risk several pathologies. FA known be sensitive compound, easily degraded by pH, light, heat food processing. Food irradiation process exposing ionizing radiations...
Numerous isothiocyanates (ITCs) are poorly soluble in water which causes their precipitation aqueous mobile phases used reversed phase liquid chromatography (RP-LC), thus impacting the accuracy of quantification. By comparing amounts ITCs injected and released from column, losses could be estimated at 5–32% depending on polarities concentrations. Results dramatically improved terms separation quantification using RP-LC with a mercaptoethanol precolumn derivatization aimed avoiding...
Soft and red smear cheeses are frequently contaminated by Listeria monocytogenes , sometimes at relatively high concentration (< 10 5 CFUg ‐1 ). This bacterium is radiosensitive (D value of approximately 0.45 kGy) but irradiation the whole cheese X‐rays induced off‐flavours when dose exceeded 1.0 kGy. Irradiation could be effective in eliminating L. only from lightly (> 2 CFU g appears rind (where pH greater than 6.3) never grows core cheese. Under these conditions, a specific after...
A pressurized liquid extraction (PLE) method using phosphate buffer as solvent was applied for folic acid (FA) from fortified wheat flours and compared to a standard solid-liquid (SLE) method. Extracted FA quantified by reverse phase high-performance chromatography (RP-HPLC) hyphenated with phenyl column an absorption photometric detector (λ = 280 nm). Detection quantification limits were 0.12 0.4 ng, respectively, corresponding 0.06 0.2 μg g(-1) of analyzed flour. Equivalent contents found...
With the aim of evaluating antigerminative activity plant extracts, a miniaturized assay using 96-well plates (WP assay) was developed and compared to long-established Petri dishes (PD assay). The WP yielded results comparable those PD an ethanolic extract Himalayan balsam lawsone as standard. It also allowed needed volume test solution be cut by half number required cress seeds more than 1.5. then successfully applied various extracts balsam, molecules (2,4-dichlorophenoxyacetic acid...