A5100421807- Reproductive Biology and Fertility
- Ovarian function and disorders
- Birth, Development, and Health
- Acute Lymphoblastic Leukemia research
- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Renal and related cancers
- Rabbits: Nutrition, Reproduction, Health
- Animal Genetics and Reproduction
- CAR-T cell therapy research
- Menopause: Health Impacts and Treatments
- Ovarian cancer diagnosis and treatment
- Chronic Myeloid Leukemia Treatments
Guangzhou University of Chinese Medicine
2020-2025
Minzu University of China
2024
First Affiliated Hospital of Harbin Medical University
2021
Harbin Medical University
2021
Guangdong Provincial Hospital of Traditional Chinese Medicine
2021
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2020
Wenzhou Medical University
2020
Premature ovarian insufficiency (POI), a condition impacting women under 40, is rising globally, posing significant risks to fertility, bone health, and cardiovascular function. Conventional hormone replacement therapy (HRT) alleviates symptoms but fails restore Our prior studies have demonstrated that the Huyang Yangkun (HYYK) formula effectively supports menstrual cycle frequency menopause-related in POI patients. This study aims evaluate efficacy safety of HYYK formula, traditional...
Huyang Yangkun Formula (HYYKF) was developed based on theory of traditional Chinese medicine as well clinical experience and used to improve ovarian function premature insufficiency (POI) patients. Transplantation embryonic stem cells (ESCs) has great potential in improving POI, studies have confirmed that promoted the treatment effect ESCs. In present study, we compared combining HYYKF ESCs, single ESCs intervention POI mice explore combination function.C57BL/6 were create a model by 15-day...
Premature ovarian insufficiency (POI) is a common female endocrine disease that closely linked to function. Danggui Buxue Tang (DBT) classic prescription of traditional Chinese medicine helpful for rescuing However, the mechanism by which DBT rescues function remains unclear. This study explored molecular with respect apoptosis and related signals in cells. The quality control was performed HPLC. After intervention POI rat model, serum AMH/FSH/LH/E2 levels were detected ELISA, follicles at...
Abstract Neurotrophin‐3 (NT‐3) acts as an important growth factor to stimulate and control tissue development. The NT‐3 receptor, TRKC, is expressed in rat testis. Its function regulation of stem Leydig cell development its underlying mechanism remain unknown. Here, we reported the role regulate vivo vitro. Ethane dimethane sulphonate was used kill all cells adult testis, (10 100 ng/testis) injected intratesticularly from 14th day after ethane injection for 14 days. significantly reduced...
<title>Abstract</title> Granulosa cells are not only important supporting in follicular development, but also the main secreting steroids. The proliferation of GCs and steroid hormone synthesis play a key role development atresia. In this experiment, were isolated by fluid aspiration, identified immunofluorescence technique. effects different concentrations NAC (50, 100, 500, 1000 µmol/L) on sheep with regards to antioxidant levels, proliferation, apoptosis, secretion investigated. PI3K/AKT...