Michael Fana

ORCID: 0000-0003-4256-6961
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About
Contact & Profiles
Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Intracranial Aneurysms: Treatment and Complications
  • Dendrimers and Hyperbranched Polymers
  • Neurosurgical Procedures and Complications
  • Spine and Intervertebral Disc Pathology
  • Systemic Lupus Erythematosus Research
  • Renal and Vascular Pathologies
  • Head and Neck Surgical Oncology
  • Spinal Hematomas and Complications
  • Spinal Fractures and Fixation Techniques
  • Cervical and Thoracic Myelopathy
  • Cerebral Venous Sinus Thrombosis
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Atrial Fibrillation Management and Outcomes
  • Psychosomatic Disorders and Their Treatments
  • Vascular Malformations Diagnosis and Treatment
  • Spinal Cord Injury Research
  • Stroke Rehabilitation and Recovery
  • Moyamoya disease diagnosis and treatment
  • Epilepsy research and treatment
  • Adrenal and Paraganglionic Tumors
  • Colorectal Cancer Surgical Treatments
  • Infectious Aortic and Vascular Conditions
  • Neurological Complications and Syndromes

Henry Ford Health System
2022-2025

Michigan United
2023-2025

Henry Ford Hospital
2022-2024

Central Michigan University
2019-2022

Neurological Surgery
2022

Field Neurosciences Institute
2020-2022

University of Pittsburgh
2022

Beaumont Hospital, Royal Oak
2022

Banner - University Medical Center Tucson
2022

Ballad Health
2022

The central circadian pacemaker, the suprachiasmatic nucleus (SCN), encodes day length information by mechanisms that are not well understood. Here, we report genetic ablation of miR-132/212 alters entrainment to different lengths and non-24 hr day-night cycles, as photoperiodic regulation Period2 expression in SCN. SCN neurons from miR-132/212-deficient mice have significantly reduced dendritic spine density, along with altered methyl CpG-binding protein (MeCP2) rhythms. In Syrian hamsters,...

10.1016/j.celrep.2017.03.057 article EN cc-by-nc-nd Cell Reports 2017-04-01

Introduction: Mechanical thrombectomy (MT) devices were fundamentally designed for the treatment of cardioembolic (CE) strokes despite that 10-20% large vessel occlusions (LVO) are caused by artery atherosclerosis (LAA), which may not respond comparably. Therefore, differentiation between LAA and non-LAA LVO be critical selecting ideal MT technique. Here, we construct an algorithm use in emergent setting pre-operatively to differentiate using clinical radiographic features. Methods: Using...

10.1161/str.56.suppl_1.tp258 article EN Stroke 2025-01-30

Background Differentiating between intra-cerebral atherosclerotic disease (ICAD) and non-ICAD large vessel occlusion (LVO) is crucial for selecting the appropriate mechanical thrombectomy (MT) technique device. We developed an algorithm to predict LVO etiology using clinical radiographic features in emergent setting. Methods conducted a retrospective chart review of middle cerebral artery (MCA) occlusions treated with MT confirmed as ICAD or non-ICAD. recorded common risk factors from CT...

10.1101/2025.03.26.25324735 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2025-03-28

To determine associations between the rate of physical restraint and demographic variables such as body mass index (BMI), ethnicity, sex, age in emergency department (ED) along with clinical various psychiatric diagnoses medications.This 6-month (October 1, 2016-March 30, 2017) retrospective chart review was conducted ED a community hospital, which is also teaching institution for medical students residents but does not have access to psychiatry consultations via phone or person. A total 165...

10.4088/pcc.19m02471 article EN The Primary Care Companion For CNS Disorders 2019-11-20

Purely intradural retro-odontoid synovial cysts are rarely reported in neurosurgical literature, particularly the absence of associated bony erosions. We present case a 57-year-old Native American male with cyst and history chronic refractory neck pain that was adequately decompressed via an endoscopic-assisted far-lateral approach using C1-2 hemilaminectomy, obviating vertebral artery (VA) transposition, instability, need for instrumented fusion. The patient presented to our clinic several...

10.7759/cureus.21715 article EN Cureus 2022-01-29

Introduction: Patients with acute ischemic stroke (AIS) often present conditions that require emergent anticoagulation (AC) other than atrial fibrillation (AF). Current literature lacks guidance on the safety of administering AC when both pathologies coexist. Therefore, we tend to rely studies investigating AF and AIS for recommendations. Methods: We retrospectively reviewed data patients who had a non-AF indication (e.g., intraluminal floating thrombus, intracardiac coronary syndrome, limb...

10.1161/str.55.suppl_1.wp11 article EN Stroke 2024-02-01

Intracranial dural arteriovenous fistula (AVF) is a rare condition; it usually described as an arterio-venous shunt within the dura with sinus or cortical drainage. AVFs can occur anywhere in central nervous system. Most commonly, they are found at transverse sinus, and this location reported 50% of all cases. Symptoms Dural vary widely according to their location. Progressive thalamic dementia due venous hypertension draining veins example. Herein, we present patient reversible progressive...

10.1212/wnl.0000000000205192 article EN Neurology 2024-04-09

Chronic subdural hematomas (cSDH) are collection of blood for which the current treatment option remains as surgical evacuation due to recurring focal inflammation and angiogenesis. An adjunctive therapeutic intervention is endovascular embolization middle meningeal artery (MMA) cease prolific cycle Few investigations have been made into indications this modality regarding timeline hematoma size non-surgical candidates with acute-on-chronic hematomas.

10.1177/19418744241285275 article EN The Neurohospitalist 2024-09-14

The Nazi regime held power for well over a decade in Germany and were steadfast their anti-Semitic agenda. Among the massive cohort of immigrants to America approximately 5056 Jewish physicians, including several highly esteemed neurologists neuroscientists time. Emigrating new world proved difficult provided challenges by way language barriers, roadblocks medical careers, problems integrating into an alien system training clinical practice. In this article, authors examine tumultuous...

10.3171/2019.6.focus19340 article EN Neurosurgical FOCUS 2019-09-01

10.1016/j.clineuro.2022.107199 article EN Clinical Neurology and Neurosurgery 2022-03-04

Acute myeloid leukemia (AML) is a disorder of the cell line that can manifest infrequently as granulocytic sarcoma with infiltration into bone and soft tissue. Consequently, cranial nerve neuropathy due to AML result in variable neurological deficits, including facial palsy. Here, we present case patient presenting unilateral palsy evidence cerebrospinal fluid (CSF) cytology bilateral opacification mastoid air cells suggestive process. Patient demonstrated improvement after administration...

10.7759/cureus.23710 article EN Cureus 2022-03-31

Cerebrovascular aneurysms of the supraclinoid region are a technical challenge and can be particularly difficult to treat when greater than 25 mm in diameter. Such giant approached with various skull-based endovascular surgical techniques, advent Pipeline embolization stent presents new treatment modality. Previously used for small aneurysms, device (PED) is flow diverter that has more recently been investigated its use few studies date published about procedural outcomes. Here, we highlight...

10.7759/cureus.23674 article EN Cureus 2022-03-31

10.1016/j.rpor.2013.03.776 article EN publisher-specific-oa Reports of Practical Oncology & Radiotherapy 2013-06-01
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