A5074347876- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Surgical Treatments
- Hernia repair and management
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Pancreatic and Hepatic Oncology Research
- Diverticular Disease and Complications
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Stoma care and complications
- Pharmacogenetics and Drug Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Neonatal Health and Biochemistry
- Colorectal and Anal Carcinomas
- Pelvic and Acetabular Injuries
- Liver Disease Diagnosis and Treatment
- Renal function and acid-base balance
- Eicosanoids and Hypertension Pharmacology
- Urinary Bladder and Prostate Research
- Esophageal Cancer Research and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Inflammatory mediators and NSAID effects
Central Finland Health Care District
2011-2023
University of Oulu
1976-1997
University of Eastern Finland
1992
Oulu University Hospital
1977-1987
National Institutes of Health
1986
National Cancer Institute
1986
University of Helsinki
1982
Quality of life is an important outcome measure that has to be considered when deciding treatment strategy for rectal cancer. The aim this study was find out the impact surgery-related adverse effects on quality life.The RAND-36 questionnaire and questionnaires assessing urinary, sexual, bowel dysfunction were administered 94 patients with no sign recurrence a minimum one year after curative surgery. Results compared age-matched gender-matched general population.Eighty-two (87 percent)...
This study was undertaken to find out the incidence of rectal prolapse.Ninety-nine patients operated on for prolapse at Jyväskylä Central Hospital were studied. Patients between 1988 and 1998 studied retrospectively from hospital records using chart review thirty-five 1999 2002 prospectively our proctologic database.The annual diagnosed complete in district Finland mean 2.5 (range, 0.79-6.08) per 100 000 population. There ten men (10 percent) 89 women (90 percent). Median age 69 21-91)...
The objective of the study was to examine role microsatellite instability (MSI) and BRAFV600Emutation in colorectal cancer (CRC) by categorising patients into more detailed subtypes based on tumour characteristics. Tumour samples from 762 population-based with sporadic CRC were analysed for MSI BRAFV600E immunohistochemistry. Patient survival followed-up a median 5.2 years. Compared stable (MSS) CRC, prognostic better disease-free (DFS; 5 years: 85.8% vs 75.3%, 10 72.9%, P=0.027; HR 0.49, CI...
Stapled hemorrhoidectomy may be associated with less pain and faster recovery than conventional for prolapsing hemorrhoids. Therefore, the outcome of stapled was compared that diathermy in a randomized, controlled trial.Sixty patients third-degree hemorrhoids were randomly assigned to (n = 30) or day-case setting. Visual analog scale used postoperative scoring. Surgical functional assessed at six weeks one year after surgery.Operation time median 21 (range, 11-59) minutes group. 22 14-40)...
Four cytochrome P-450 enzyme activities, 7-ethoxyresorufin O-deethylase (ERDE), coumarin 7-hydroxylase (CH), 7-ethoxycoumarin (ECDE) and aryl hydrocarbon hydroxylase (AHH) were measured in human liver needle biopsy samples from smokers non-smokers. Cigarette smoking was verified quantitated by measuring plasma cotinine levels. Enzyme inhibitory monoclonal antibodies (MAb) to a 3-methylcholanthrene-induced (MAb 1-7-1) phenobarbitone-induced 2-66-3) rat hepatic used measure the contribution of...
Objective To assess the feasibility and evaluate performance of a relaunched colorectal cancer (CRC) screening programme with different cut-offs for men women. Design Population-based registry study. Setting Nine municipalities in Finland which started CRC faecal immunochemical test (FIT) April 2019 cut-off levels 70 µg Hg/g faeces 25 Participants Men (n=13 059) women (n=14 669) aged 60–66 years invited to during first year. Outcome measures Participation rates, positivity detection rates...
This study was undertaken to evaluate the efficacy and safety of laparoscopic repair for rectal prolapse.A case-control undertaken. The case group consisted a consecutive series patients who underwent prolapse between February 1993 June 2000. control open October 1987 January 2000.There were 53 in each group. groups matched according operation type, gender, age. Median operative time longer than (resection rectopexy 210 vs. 117 minutes, 127.5 72 respectively). postoperative hospital stay...
BACKGROUND: Parastomal hernias are common with permanent colostomies and prone to complications. The short-term results of trials parastomal hernia prevention widely published, but long-term scarce. OBJECTIVE: aim the study is detect effects safety preventive intra-abdominal mesh. DESIGN: This a follow-up previous prospective randomized, controlled multicenter trial. SETTINGS: was conducted at 2 university hospitals 3 central in Finland. PATIENTS: Patients who had laparoscopic...
<i>Purpose:</i> The purpose of this study was to examine the outcome patients whom a temporary stoma constructed in our institution. <i>Method:</i> operated on over an 8-year period prospectively examined. Special attention given influence age complications and closure stomas. <i>Results:</i> Between 1989 1996, total 349 intestinal stomas were 342 patients. In 141 these patients, could be considered as temporary. 30-day mortality rate 7%. overall...
BACKGROUND: Information is needed on long-term functional results, sequelas, and outcome predictors for laparoscopic ventral mesh rectopexy. OBJECTIVE: The purpose of this study was to evaluate function postventral rectopexy in patients with external rectal prolapse or internal a large cohort identify the possible effects patient-related factors operative technical details patient-reported outcomes. DESIGN: This retrospective review cross-sectional questionnaire study. SETTINGS: Data were...
Abstract Background. To determine risk factors for third‐degree and complete third‐ or fourth‐degree anal sphincter tears in vaginal delivery. Methods. This is a retrospective comparative study. Fifty‐three women who had sustained an tear were compared with 9,178 without such complication between August 1997 October 2001. Obstetric data was collected from electronic database. The main outcome measures odds ratios. Results. In the whole study population, ratios (ORs) were: primiparity, 8.34...
This retrospective population-based study examined the impact of age and comorbidity burden on multimodal management survival from colorectal cancer (CRC). From 2000 to 2015, 1479 consecutive patients, who underwent surgical resection for CRC, were reviewed age-adjusted Charlson index (ACCI) including 19 well-defined weighted comorbidities. The ACCI was compared between low (score 0–2), intermediate 3) high ≥ 4) groups. Changes in treatment 2015 seen next a major increase laparoscopic...
PURPOSE:: Overlap sphincteroplasty is gaining popularity in the primary repair of obstetric sphincter ruptures. This study was designed to evaluate medium-term outcome overlap technique. METHODS:: Between August 1997 and October 2001, 31 consecutive females who were diagnosed with a complete third-degree or fourth-degree anal rupture underwent immediately after delivery. Thirty followed-up for median 24 months. The assessed by clinical examination, endosonography, Wexner score, pelvic floor...
Abstract Five geriatric patients with spontaneous rupture of the liver caused by hepatic malignancies were operated upon without mortality. Liver resection seems to be treatment choice, but in selected cases unresectable tumours ligation artery alone is preferable an attempt control haemorrhage packing and suture.
To compare laparoscopic non-CME colectomy with CME in two hospitals similar experience colorectal surgery.
Background and Aims: The question which patients with functional proctologic disorders truly benefit from the biofeedback has not been equivocally resolved. aim of this study was to assess our results therapy in anal incontinence or constipation. Material Methods: Fifty-two consecutive who were treated between January 1998 March 2002 studied. Data collected database. Results: Of twenty-two underwent during period, twenty had affecting quality life. Twelve (60 percent) benefited as judged by...