A5043230342- Transcranial Magnetic Stimulation Studies
- Neural and Behavioral Psychology Studies
- Attention Deficit Hyperactivity Disorder
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Obsessive-Compulsive Spectrum Disorders
- Muscle activation and electromyography studies
- Neurological disorders and treatments
- Children's Physical and Motor Development
- Mental Health Research Topics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Impact of Technology on Adolescents
- Eating Disorders and Behaviors
- Heart Rate Variability and Autonomic Control
- Hemispheric Asymmetry in Neuroscience
- Stroke Rehabilitation and Recovery
- Cardiomyopathy and Myosin Studies
- Olfactory and Sensory Function Studies
- Neuroscience and Music Perception
- Mind wandering and attention
- Personality Disorders and Psychopathology
- Psychological and Temporal Perspectives Research
- Treatment of Major Depression
- Neuroscience and Neural Engineering
- Child Development and Digital Technology
Ben-Gurion University of the Negev
2016-2025
The Technological College of Beer Sheva
2014
BackgroundObsessive Compulsive Disorder (OCD) is a chronic and disabling disorder with poor response to pharmacological treatments. Converging evidences suggest that OCD patients suffer from dysfunction of the cortico-striato-thalamo-cortical (CSTC) circuit, including in medial prefrontal cortex (mPFC) anterior cingulate (ACC).ObjectiveTo examine whether modulation mPFC-ACC activity by deep transcranial magnetic stimulation (DTMS) affects symptoms.MethodsTreatment resistant participants were...
BackgroundAlcohol addiction is associated with a high disease burden, and treatment options are limited. In proof-of-concept study, we used deep repetitive transcranial magnetic stimulation (dTMS) to target circuitry the pathophysiology of alcohol addiction. We evaluated clinical outcomes explored neural signatures using functional resonance imaging.MethodsThis was double-blind, randomized, sham-controlled trial. A total 51 recently abstinent treatment-seeking patients use disorder (moderate...
Smartphone usage is now integral to human behavior. Recent studies associate extensive with a range of debilitating effects. We sought determine whether excessive accompanied by measurable neural, cognitive and behavioral changes.Subjects lacking previous experience smartphones (n = 35) were compared matched group heavy smartphone users 16) on numerous electrophysiological measures recorded using electroencephalogram (EEG) combined transcranial magnetic stimulation (TMS) over the right...
BACKGROUND. Major depressive disorder (MDD) can benefit from novel interventions and personalization. Deep transcranial magnetic stimulation (Deep TMS) targeting the lateral prefrontal cortex (LPFC) using H1 coil was FDA cleared for treatment of MDD. However, recent preliminary data indicate that medial (MPFC) H7 might induce outcomes are as good or even better. Here, we explored whether TMS MPFC is noninferior to LPFC electrophysiological clinical markers patient selection be identified.
Attention deficit hyperactivity disorder (ADHD) is a prevalent with effective pharmacological treatment that benefits most patients. However, about one-third fail to benefit while others search non-pharmacological alternatives, and for those options are scarce. One alternative option alter abnormal right prefrontal cortex (rPFC) activity, given rPFC abnormality has been repeatedly implicated in ADHD neurophathology. Here, we evaluated whether targeting the multiple sessions of repetitive...
Objectives: Recent studies support the possible effectiveness of repetitive transcranial magnetic stimulation (rTMS) as a treatment for attention deficit hyperactivity disorder (ADHD). The objective this study was to evaluate safety and efficacy bilateral prefrontal deep rTMS adult ADHD.Methods: Twenty-six ADHD patients were randomised blindly sham or actual TMS (dTMS). Twenty daily sessions conducted using H5 dTMS coil (Brainsway, IL) in order stimulate cortex at 120% motor threshold high...
Despite research regarding emotional processing, it is still unclear whether fear-evoking stimuli are processed when they irrelevant and attention oriented elsewhere. In this study, 63 healthy university students with high fear from snakes or spiders participated in two different experiments. an modification of the spatial cueing task, 31 subjects (5 males) were asked to detect a target letter while ignoring neutral fear-related distracting picture. The distribution was independently...
Children participating in the Ben‐Gurion Infant Development Study were assessed with a dynamic‐tracking version of stop‐signal task at age 5 years. The sample consisted 60 males. Stop‐signal reaction time ( SSRT ) was correlated concurrent ratings child's attention deficit hyperactivity disorder ADHD symptoms. Paternal symptoms measured early infancy predicted performance task: inattentiveness , whereas error proportion. Maternal not child task. A subsample children, who tested while...
Both 10 Hz repetitive transcranial magnetic stimulation (rTMS) as well 18 deep TMS (dTMS) constitute effective, FDA-approved treatment protocols for depression. However, not all patients experience sufficient symptom relief after either of these protocols. Biomarker-guided stratification could aid in personalizing and thereby enhancing improvement. An individual alpha frequency (iAF)-based EEG-biomarker, Brainmarker-I, can differentially stratify to depression treatments. For instance, an...
Obesity is associated with food and eating addiction (FA), but the biobehavioral markers of this condition are poorly understood. To characterize FA, we recruited 18 healthy controls overweight/obese adults (n = 31) without 17) FA (H-C, FAOB, NFAOB, respectively) to assess alpha brain asymmetry at rest using electroencephalogram; event-related potentials following exposure high-calorie (HCF), low-calorie (LCF), nonfood (NF) images in a Stroop paradigm; reaction time reflective bias; symptoms...
Adaptive decision making requires the adjustment of behavior following an error in order to improve future performance, but obsessive compulsive disorder (OCD) patients are characterized by abnormal monitoring [[1]Modirrousta M. Meek B.P. Sareen J. Enns M.W. Impaired trial-by-trial cognitive control improves after deep repetitive transcranial magnetic stimulation.BMC Neurosci. 2015; 16: 63Crossref PubMed Scopus (20) Google Scholar,[2]Veale D. Sahakian B. Owen A. Marks I. Specific deficits...
Objectives Abnormal functional brain asymmetry and deficient response inhibition are two core symptoms of attention deficit hyperactivity disorder (ADHD). We investigated whether these inter-related they underlined by altered frontal excitability compromised interhemispheric connectivity. Methods studied issues in 52 ADHD 43 non-clinical adults comparing: (1) stop-signal reaction time (SSRT); (2) the N200 event-related potential component, which is evoked during lateralised to right...
Introduction Despite its high prevalence, the validated treatment for ADHD is chronic administration of psychostimulants, which associated with side effects and occasionally not tolerated. Deep TMS using special coil designs targeting neural networks linked neuropsychiatric disorders, may become a viable alternative. Objectives Comparison rTMS deep, figure-8 sham coils on symptoms. Methods In current randomized, sham-controlled study, adult patients received 15 daily sessions high-frequency...