A5088719220- Multiple Myeloma Research and Treatments
- Peripheral Neuropathies and Disorders
- Soft tissue tumor case studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Phytochemistry and Biological Activities
- Adipose Tissue and Metabolism
- Cancer Treatment and Pharmacology
- Flavonoids in Medical Research
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Barrier Structure and Function Studies
- Sarcoma Diagnosis and Treatment
- Natural product bioactivities and synthesis
- Stress Responses and Cortisol
- Diet and metabolism studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Soft tissue tumors and treatment
- Cerebrovascular and genetic disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Research on Leishmaniasis Studies
- Connexins and lens biology
- Congenital Heart Disease Studies
- Circadian rhythm and melatonin
- Alzheimer's disease research and treatments
- Vascular anomalies and interventions
Yale University
2024-2025
Yale Cancer Center
2024
Harvard University
2020-2022
Smith-Kettlewell Eye Research Institute
2020-2022
Massachusetts Eye and Ear Infirmary
2020-2022
Hsin Sheng College of Medical Care and Management
2013
Florida State University
1995-1996
Cerebral amyloid angiopathy is a small vessel disease associated with cortical microbleeds and lobar intracerebral haemorrhage due to amyloid-β deposition in the walls of leptomeningeal arterioles. The mechanisms cerebral angiopathy-related remain largely unknown. Recent work has demonstrated that ruptured blood vessels have limited (or no) at site bleeding evidence local vascular remodelling. We hypothesized blood-brain barrier leakage perivascular inflammation may be involved this...
Retinal ischemia is a common cause of many retinal diseases, leading to irreversible vision impairment and blindness. Excessive neuroinflammation, including microglial activation T-cell responses, has been identified as critical factor associated with neurodegeneration in ischemia. Baicalein natural flavonoid reported have broad anti-inflammatory neuroprotective bioactivities. Herein, the effects baicalein on microglia vitro vivo were investigated. We found that exhibited robust effect...
11585 Background: Desmoid tumors are soft-tissue neoplasms, which, although unable to metastasize, can cause significant morbidity due local invasion. Currently, the first-line approach is active surveillance. For that progress during surveillance, systemic therapies be used, including nirogacestat, sorafenib, pazopanib, and cytotoxic chemotherapy. However, their optimal duration unknown. Here, we aim assess risk of treatment failure after discontinuing sorafenib before one year. Methods: We...
Abstract Background Desmoid tumors can cause morbidity due to local invasion, potentially being fatal when fast growth compromises vital structures. In this context, a timely treatment response is required. This study aims compare the activity of sorafenib and anthracycline‐containing regimens during first year treatment. Methods The authors conducted multi‐institutional retrospective analysis desmoid tumor patients treated with either or an regimen over 1 year. primary end point was overall...