A5103252949- Liver Disease and Transplantation
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Liver Disease Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Infective Endocarditis Diagnosis and Management
- Pulmonary Hypertension Research and Treatments
- Diabetes Treatment and Management
- Blood Pressure and Hypertension Studies
- Cardiac Valve Diseases and Treatments
- Antimicrobial Resistance in Staphylococcus
- Advanced MRI Techniques and Applications
- Cardiac Structural Anomalies and Repair
- Viral Infections and Immunology Research
- Hormonal Regulation and Hypertension
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Renal function and acid-base balance
- Acute Myocardial Infarction Research
- Cardiovascular and Diving-Related Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Rate Variability and Autonomic Control
University of Thessaly
2024
University Hospital of Ioannina
2012-2024
Interbalkan Medical Center
2024
University of Ioannina
2008-2023
National University of Singapore
2022
University Hospital Centre Zagreb
2022
National University Heart Centre Singapore
2022
University of Zagreb
2022
Institute of Clinical and Experimental Medicine
2019
Lithuanian University of Health Sciences
2019
Type 2 diabetes mellitus (T2DM) is independently associated with an increased risk for cardiovascular diseases that primarily due to the early development of advanced atherosclerotic vascular changes. The aim our study was investigate predictors dysfunction in T2DM patients.We studied 165 patients without known macrovascular or microvascular disease. Standard demographic (age, gender, factors, medications), clinical (body mass index, blood pressure) and laboratory (glucose, glycated...
Background and aim A multicentre nationwide surveillance study was conducted in Greek hospitals to evaluate epidemiology of carbapenemase-producing Klebsiella pneumoniae clinical isolates, their susceptibilities last-line antibiotics. Methods: Minimum inhibitory concentrations (MICs) were evaluated by Etest, colistin MICs also broth microdilution SensiTest (now known as ComASP) Colistin. Carbapenemase genes detected PCR. Clonal relatedness assessed PFGE. Isolates prospectively collected...
Introduction Within this longitudinal study we investigated the association of inflammation markers C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor-α (TNFα) endothelial dysfunction intercellular adhesion molecule-1 (ICAM-1) vascular cell (VCAM-1) with left ventricular mass indexed for height2·71 (LVMI) in hypertensive predialysis CKD patients. Material Methods From 2004 to 2005, 182 incident consecutive adult patients from outpatient clinics two hospitals Greece...
Abstract Objective: Increased body mass index (BMI) has been paradoxically inversely associated with the presence of angiographic coronary artery disease (CAD). Central obesity measures, considered to be more appropriate for assessing obesity‐related cardiovascular risk, have little studied in relation CAD. The aim was investigate association central CAD as well prognostic significance measures prediction when added other risk factors. Design and Methods: Patients suspected stable (n = 403,...
Pioglitazone and metformin are insulin sensitisers used for the treatment of T2DM. The effects pioglitazone on endothelial function, assessed by FMD, in T2DM patients treated with sulfonylureas were compared. Patients randomised to receive ( n = 15) 30 mg once daily or 16) 850 twice six months. significantly decreased fasting insulin, HbA 1C HOMA-IR p < 0.05 all) increased FMD 0.002). Metformin induced a significant decrease 0.02) only trend increase 0.08). greater improvement...
Increased arterial stiffness assessed by carotid-femoral pulse wave velocity (CFPWV) and central augmentation index (AIx), has been associated with a worse cardiovascular prognosis increased prevalence of angiographic coronary artery disease (CAD). Obesity, well-recognized risk factor, related to stiffness, although not consistently. The aim this work was investigate the association indices obesity measures in patients undergoing angiography study any potential CAD relation obesity.Three...
Background. Oxidative stress is a hallmark of CKD and this alteration strongly implicated in LV hypertrophy dysfunction. Methods Patients. We resorted to the strongest genetic biomarker paraoxonase-1 (PON1) activity, Q192R variant PON1 gene, unbiasedly assess (Mendelian randomization) cross-sectional longitudinal association gene-variant with mass function 206 patients 3-year follow-up. Results. The R allele polymorphism associated oxidative as assessed by plasma 8-isoPGF2α (P = 0.03) was...
Thiazolidinediones, used for the treatment of patients with type 2 diabetes mellitus (DM2), are associated an increased incidence heart failure. We sought to investigate effects pioglitazone on novel echocardiographic indices left ventricular (LV) diastolic function in DM2 LV dysfunction (LVDD).Eighty-eight asymptomatic metformin and/or sulfonylureas, aged 64.5 ± 7.7 years, without known cardiovascular disease, normal systolic and evidence LVDD were randomly assigned 30 mg/day (n = 42) or...
An increased incidence of myocardial infarction with rosiglitazone in patients type 2 diabetes mellitus (T2DM) has been reported. This study aimed to assess the effect on endothelial function, assessed by flow-mediated dilation (FMD), 34 advanced T2DM treated insulin without known cardiovascular disease. Patients were randomised into two groups: no additional treatment was given 17 patients, while for 6 months. Addition significantly reduced glycosylated haemoglobin (HbA 1c ) ( p <...
The goal of this study was to evaluate the prevalence depression and anxiety in patients subjected myocardial perfusion imaging (MPI) with 99mTc tetrofosmin stress-rest single-photon emission computer tomography (SPECT), their impact on cardiological events or disease.Patients referred Nuclear Medicine Department for MPI-SPECT were asked fulfill Zung Self-Rating Depression Scale (ZDS) Hamilton questionnaire (HAQ). Among 213 who completed ZDS HAQ, 80 (59 males 21 females) selected because...
In recent years, concerns have been raised on the potential adverse effects of nonselective beta-blockers, and particularly carvedilol, renal perfusion survival in decompensated cirrhosis with ascites. We investigated long-term impact converting propranolol to carvedilol systemic hemodynamics function, outcome patients stable grade II/III nonrefractory ascites.Ninety-six treated for esophageal varices' bleeding prophylaxis were prospectively evaluated. These randomized a 2:1 ratio switch at...