Michail Mitsis

ORCID: 0000-0003-1646-4136
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About
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Research Areas
  • Cancer Genomics and Diagnostics
  • Genetic factors in colorectal cancer
  • Gastrointestinal Tumor Research and Treatment
  • Gastric Cancer Management and Outcomes
  • Colorectal Cancer Treatments and Studies
  • Lung Cancer Diagnosis and Treatment
  • Renal Transplantation Outcomes and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • Lung Cancer Treatments and Mutations
  • Cancer Cells and Metastasis
  • Metastasis and carcinoma case studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Aortic aneurysm repair treatments
  • Pancreatic and Hepatic Oncology Research
  • Renal and Vascular Pathologies
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Central Venous Catheters and Hemodialysis
  • Intestinal and Peritoneal Adhesions
  • Bioactive Compounds and Antitumor Agents
  • Intestinal Malrotation and Obstruction Disorders
  • Mathematical Biology Tumor Growth
  • Cerebrovascular and Carotid Artery Diseases
  • Intraperitoneal and Appendiceal Malignancies
  • Gastrointestinal disorders and treatments
  • Colorectal and Anal Carcinomas

University Hospital of Ioannina
2016-2025

University of Ioannina
2014-2024

Aim: Traumatic brain injury (TBI) is a serious health concern. We set out to investigate the role of neutrophil-to-lymphocytes ratio (NLR) at admission for predicting need computed tomography (CT) in mild-TBI. Materials & methods: A retrospective study adult patients who presented with mild-TBI Results: One hundred and thirty met inclusion criteria. Seventy-four had positive CT-findings. The mean NLR-levels presentations were 5.6 ± 4.8. Patients CT-findings significant higher NLR-levels....

10.2217/bmm-2020-0150 article EN Biomarkers in Medicine 2020-08-01

Gallbladder cancer (GBC), while infrequent, is the predominant malignancy of biliary tract. The absence clinical symptoms in conjunction with aggressive behavior contributes to delayed diagnosis and unfavorable prognosis. This condition typically remains asymptomatic its initial stages, making detection challenging. Herein, we report a case adenosquamous carcinoma gallbladder 74-year-old Caucasian woman who was admitted due anemia, gastrointestinal bleeding, abdominal pain. Computed...

10.7759/cureus.77811 article EN Cureus 2025-01-22

Traumatic brain injury has been associated with increased blood glucose levels. In the present study, we set out to investigate if level in mild head trauma could predict need for CT. One hundred fifty-nine patients minor TBI (GCS 13-15) and a mean age of 44.8 ± 23.8 years were included study. The most common mechanism was falls. Patients positive CT findings had significantly higher levels than negative findings. Using ROC curve analysis, serum 120 mg dl-1 optimal cutoff value detection...

10.1155/2019/1065254 article EN Disease Markers 2019-04-09

Maladaptive activation of the immune system plays a key role in pathogenesis chronic kidney disease (CKD). Our aim was to investigate differences circulating cells between type 2 cardiorenal syndrome (CRS-2) patients and CKD without cardiovascular (CVD). CRS-2 were prospectively followed up, with primary endpoint being all-cause mortality.A total 39 stable males 24 male matched for eGFR (CKD-EPI) enrolled. A selected panel cell subsets measured by flow cytometry.Compared patients, displayed...

10.3390/biomedicines11041029 article EN cc-by Biomedicines 2023-03-27

Cell-cycle analysis has shown the presence of aneuploidy to be associated with poor prognosis. We developed an innovative rapid cell-cycle protocol (the Ioannina protocol) that permitted intraoperative identification neoplastic cells in a plethora malignancies. Herein, we aimed investigate potential role characterization gynecological Women who underwent surgery for malignancies our institution over three-year period were included this study. Permanent section pathology evaluation was used...

10.3390/biology11091339 article EN cc-by Biology 2022-09-11

Introduction The mechanisms underlying high drug resistance and relapse rates after multi-modal treatment in patients with colorectal cancer (CRC) liver metastasis (LM) remain poorly understood. Objective We evaluate the potential translational implications of intra-patient heterogeneity (IPH) comprising primary matched metastatic intratumor (ITH) coupled circulating tumor DNA (ctDNA) variability. Methods A total 122 multi-regional perioperative liquid biopsies from 18 were analyzed via...

10.3389/fonc.2022.855463 article EN cc-by Frontiers in Oncology 2022-03-23
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