A5031173399- Spondyloarthritis Studies and Treatments
- Rheumatoid Arthritis Research and Therapies
- Psoriasis: Treatment and Pathogenesis
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Ocular Diseases and Behçet’s Syndrome
- Inflammasome and immune disorders
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Urticaria and Related Conditions
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Systemic Sclerosis and Related Diseases
- Cardiovascular Disease and Adiposity
- Vasculitis and related conditions
- COVID-19 Clinical Research Studies
- Vestibular and auditory disorders
- Salivary Gland Disorders and Functions
- Retinal and Optic Conditions
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Iron Metabolism and Disorders
- Chronic Myeloid Leukemia Treatments
- Complement system in diseases
- Cardiac Imaging and Diagnostics
- Dermatological and COVID-19 studies
- Dermatology and Skin Diseases
Selçuk University
2013-2025
Selçuk Üniversitesi Tıp Fakültesi Hastanesi
2019-2024
Hacettepe University
2015-2021
Usak University
2020-2021
Rize Devlet Hastanesi
2021
Ege University
2015-2019
Marmara University
2015-2019
Kutahya Saglik Bilimleri Universitesi
2019
Sağlık Bilimleri Üniversitesi
2019
Kahramanmaraş Sütçü İmam University
2019
Psoriatic arthritis (PsA) has a genetic background. Approximately 40% of patients with psoriasis or PsA have family history PsA, which may affect disease features. The aim this study was to assess the effects and on phenotypes.Data from 1,393 recruited in longitudinal, multicenter Arthritis International Database were analyzed. and/or characteristics investigated using logistic regression.A total 444 (31.9%) had PsA. These more frequently women, earlier onset psoriasis, frequent nail...
To assess bladder toxicity of cyclophosphamide (CYC) and uroprotective effect mesna in rheumatic diseases.Data 1018 patients (725 women/293 men) treated with CYC were evaluated this retrospective study. All the following information was obtained: cumulative dose, route administration, duration therapy, concomitant usage, hemorrhagic cystitis. Cox proportional hazard model used for statistics.We identified 17 (1.67%) cystitis 2 (0.19%) cancer 4224 patient-years. The median time diagnosis to...
There is a lack of real-life studies on interleukin-17 (IL-17) inhibition in psoriatic arthritis (PsA). We assessed 6- and 12-month effectiveness (i.e., retention, remission, low disease activity [LDA], response rates) the IL-17 inhibitor secukinumab PsA patients overall across 1) number prior biologic/targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs), 2) years since diagnosis, 3) European registries.Thirteen quality registries rheumatology participating Spondyloarthritis...
Abstract Clinical data on the use of tumour necrosis factor inhibitors (TNFi) in late-onset ankylosing spondylitis (LoAS) are limited. The present study aimed to evaluate efficacy, safety, and treatment adherence associated with initial TNFi therapy biologic naive patients diagnosed LoAS. Patients whose age onset was ≥ 45 years < were classified as having LoAS YoAS, respectively, based symptom onset. There 2573 YoAS 281 Baseline disease activity measures similar between groups. No...
Abstract Aim Familial Mediterranean fever ( FMF ) is the most common autoinflammatory disease. One of characteristics this disease its young age predominance. Nearly 90% patients experience flares during early adult periods. Currently there are limited data for comparison versus late onset and therefore primary aim study was to investigate these two subsets with regard their certain demographic, clinical genetic differences. Methods Early (≤ 20 years, Group 1) (> 2) were identified from...
Aims: We aimed to evaluate the effect of comorbidities on first tumor necrosis factor inhibitor (TNFi) treatment response and retention in patients with rheumatoid arthritis (RA). Methods: The study included adult RA (with M05 M06 ICD codes) registered TURKBIO database receiving their TNFi treatment. Data demographic, clinical, laboratory features, disease activity scores, other follow-up parameters (at beginning months 6 12) were collected. Log-Rank test Kaplan-Meier curve used determine...
<b><i>Objective:</i></b> The purpose of this experimental study was to evaluate the efficacy hesperidin (HES) in protecting against methotrexate (MTX)-induced intestinal damage using histopathological and immunohistochemical techniques. <b><i>Materials Methods:</i></b> Seventy-eight male Wistar albino rats were divided into 4 groups that received (a) saline only (control group), n = 19; (b) HES only, (c) MTX 19, (d) plus HES, 21. On first day...
TURKBIO registry, established in 2011, is the first nationwide biological database Turkey. This study aimed to provide an overview of data collected by June 2018.The registry included adult patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), nonradiographic axial spondyloarthritis (nr-AxSpA), and psoriatic (PsA). Demographic clinical features, disease activity markers, other follow-up parameters, current previous treat- ments, adverse events were registered electronically...
Ankylosing spondylitis (AS) is a rheumatic disease characterized by chronic inflammation. The aim of this study was to evaluate the functions cochlea and vestibular system in patients with AS. group consisted 32 AS 30 healthy volunteers as control group. Otorhinolaryngologic examinations were performed all together pure-tone audiometry, speech tests, impedancemetry, transient evoked otoacoustic emission (TEOAE) electronystagmography (ENG). A significant difference found between 2 groups...
The management of acute respiratory distress syndrome (ARDS) was investigated with the use heliox in an experimental model.To investigate whether can be considered a new therapeutic approach ARDS.ARDS designed Wistar albino male rats, 250-300 g weight, by intratracheal instillation physiological saline solution. Anesthezied and tracheotomized rats ARDS were pressure-controlled ventilated. At end 210 min, helium gas tried. All assigned to two groups: Group 1 (n = 10) control group, given no...
Objective Atherosclerosis is a chronic, progressive, inflammatory disease. Recognition of subclinical atherosclerotic vascular changes before clinical manifestation in an asymptomatic population important for risk stratification and optimal management, which finally leads to the prevention cardiovascular We aimed determine premature atherosclerosis by evaluating epicardial adipose tissue thickness (EATT) arterial stiffness parameters patients with ankylosing spondylitis (AS).Methods...
Systemic lupus erythematosus (SLE) is a chronic disease that affects many organ systems and manifests broad spectrum of laboratory clinical features. SLE patients have an increased risk developing cardiovascular disease. The aim this study was to evaluate inhomogeneities repolarization by using Tpeak -Tend (Tp-e) interval Tp-e/QT ratio were measured from the 12-lead surface electrocardiogram (ECG) in with SLE.This included 69 (69 females; mean age 35.8 ± 10.2) 57 control subjects (57 34.5...