A5034230946- Amyloidosis: Diagnosis, Treatment, Outcomes
- Systemic Sclerosis and Related Diseases
- Spondyloarthritis Studies and Treatments
- Rheumatoid Arthritis Research and Therapies
- Ocular Diseases and Behçet’s Syndrome
- Autoimmune and Inflammatory Disorders Research
- Inflammasome and immune disorders
- Vasculitis and related conditions
- Otitis Media and Relapsing Polychondritis
- Urticaria and Related Conditions
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Systemic Lupus Erythematosus Research
- Immune Cell Function and Interaction
- Connective Tissue Growth Factor Research
- Cholesterol and Lipid Metabolism
- Family and Disability Support Research
- Pancreatitis Pathology and Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cancer Diagnosis and Treatment
- Mast cells and histamine
- Diagnosis and treatment of tuberculosis
- Infectious Diseases and Tuberculosis
- Dermatological and Skeletal Disorders
- Retinal and Optic Conditions
- Bone health and treatments
Istanbul Bilim University
2013-2022
Istanbul University
2004-2020
Gaziantep University
2015-2016
Ege University
2015-2016
Marmara University
2015-2016
Pamukkale University
2015-2016
Istanbul Medipol University
2014-2016
Cukurova University
2015
Hacettepe University
2015
Bursa Uludağ Üni̇versi̇tesi̇
2015
Vascular involvement is one of the major causes mortality and morbidity in Behçet disease (BD). There are no controlled studies for management vascular BD (VBD), according to EULAR recommendations, only immunosuppressive (IS) agents recommended. In this study, we aimed investigate therapeutic approaches chosen by Turkish physicians during initial event relapses VBD association different treatment options with retrospectively. Patients (n = 936, female/male: 347/589, mean age: 37.6 ± 10.8)...
Adult-onset Still's disease (AOSD) is a febrile disorder of unknown aetiology characterised by typical spiking fever, evanescent rash, arthralgia and leucocytosis.According to the diagnostic criteria AOSD, we identified 84 patients between 1990 2003. The aim this study was analyse characteristics AOSD in Turkish who were followed-up tertiary referral centre.Of 59 (70.2%) female, 25 (29.8%) male. Arthralgia (96.4%), fever (95.2%), arthritis (69%), sore throat (65.5%) rheumatoid rash (59.5%)...
To assess bladder toxicity of cyclophosphamide (CYC) and uroprotective effect mesna in rheumatic diseases.Data 1018 patients (725 women/293 men) treated with CYC were evaluated this retrospective study. All the following information was obtained: cumulative dose, route administration, duration therapy, concomitant usage, hemorrhagic cystitis. Cox proportional hazard model used for statistics.We identified 17 (1.67%) cystitis 2 (0.19%) cancer 4224 patient-years. The median time diagnosis to...
Tuberculosis continues to be a significant cause of morbidity and mortality. Although tuberculosis usually attacks the lungs, other organs can also affected, leading extrapulmonary (EPT) or disseminated tuberculosis. This study retrospectively analysed incidence, clinical sites risk factors for EPT in 252 patients with between 1 January 1991 30 June 2003. was defined as clinical, laboratory, imaging, and/or histopathological evidence mycobacterial infection site than hilar lymph nodes lung...
Objective. To assess the performance of new 2012 provisional European League Against Rheumatism (EULAR)/American College Rheumatology (ACR) polymyalgia rheumatica (PMR) clinical classification criteria in discriminating PMR from other mimicking conditions compared with previous 5 diagnostic a multicenter prospective study. Methods. Patients older than 50 years, presenting new-onset bilateral shoulder pain elevated acute-phase reactants (APR), were assessed for fulfillment and old...
Silent myocardial involvement is associated with poor prognosis in patients systemic sclerosis (SSc). Here we aimed to evaluate the subclinical left ventricular (LV) and right (RV) systolic dysfunction SSc without any cardiovascular diseases, by using both strain imaging methods, speckle tracking echocardiography (STE) real-time 3D (RT3DE).A total of 47 20 age- gender-matched healthy controls (HC) were studied. Conventional echocardiography, STE-based imaging, (Bothell, WA, USA) performed...
Recommendations for the treatment of cytokine release syndrome/macrophage activation syndrome (MAS) associated with coronavirus disease-2019 (COVID-19) are still poor quality. IL-6 is an important therapeutic target as a main mediator storm. The aim our study was to evaluate tocilizumab (TCZ) efficacy and factors affecting therapy outcome.This retrospective included 27 patients treated TCZ COVID-19-MAS. All in this were (intravenously, at dose 8 mg kg1 ) addition standard therapy. Clinical...
A relationship between the presence of amyloidosis and SAA1 genotype has been shown in recent studies (principally) familial Mediterranean fever patients. We found that rs12218 polymorphism was significantly more prevalent ankylosing spondylitis patients with amyloidosis.
<h3>Background</h3> To assess bladder toxicity of Cyclophosphamide (CYC) treatment and preventive effect 2-mercaptoethane sulfonate (Mesna) in systemic autoimmune disorders. <h3>Methods</h3> Six hundred fifty-six patients (F/M:479/177) with various disease who were treated CYC at least 3 months included to this analysis. The route administration, cumulative dosage duration as well mesna usage evaluated. Relationship between hemorrhagic cystitis six variables including assessed by survival...
<h3>Background</h3> Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by paroxysmal episodes of and serosal inflammation. The classical presentation severe recurrent abdominal pain due to serositis that lasts for one three days the resolves spontaneously. Some people experience chills prior onset fever. <h3>Objectives</h3> In this study, we aimed determine whether predictor factor or not severity score in patients with FMF. <h3>Methods</h3> Consecutively 57...
<h3>Objectives</h3> To evaluate the diagnostic and discriminative ability of new 2012 European League Against Rheumatism (EULAR)/American College Rheumatology (ACR) polymyalgia rheumatica (PMR) classification criteria compared to previous five diagnostic/classification for PMR in a multi-centre prospective study. <h3>Methods</h3> Patients older than 50 years age (n=163), presenting with onset (symptom duration ≤24 weeks) bilateral shoulder pain elevated acute phase reactants were enrolled...
<h3>Background</h3> Adult onset Still disease (AOSD) is a rare disease. Its management mostly based on expert opinion. <h3>Objectives</h3> To assess clinical features and of AOSD in large sample patients. <h3>Methods</h3> Patients from 19 centers Turkey participated this retrospective study. All the patients fulfilled Yamagushi criteria for AOSD. A case report form which included data, laboratory features, patterns, remission relapse rates treatment protocols was generated sent to...
Background: Evaluating disease activity and severity in systemic sclerosis (SSc) is crucial to define the patients who are candidate for treatment options. Objectives: We aimed investigate relationship between SSc a large cohort. Methods: This cross-sectional prospective analysis of 278 (253 females) fulfilling ACR/EULAR (2013) classification criteria SSc. Disease were calculated seperately cutaneous subsets (EscSG Medsger). The grouped as inactive if EscSG score=0, mildly active...