A5074461434- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Pulmonary Hypertension Research and Treatments
- Cardiac tumors and thrombi
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Acute Myocardial Infarction Research
- Vasculitis and related conditions
- Atrial Fibrillation Management and Outcomes
- Lipoproteins and Cardiovascular Health
- Blood Pressure and Hypertension Studies
- Aortic Disease and Treatment Approaches
- Pericarditis and Cardiac Tamponade
- Systemic Lupus Erythematosus Research
- Cerebrovascular and Carotid Artery Diseases
- COVID-19 Clinical Research Studies
- Atherosclerosis and Cardiovascular Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Congenital Heart Disease Studies
- Cardiac, Anesthesia and Surgical Outcomes
Koç University
2020-2024
Istanbul Florence Nightingale Hospital
2010-2021
Istanbul Bilim University
2007-2019
Türkiye Yüksek İhtisas Hastanesi
2013
Seoul National University Hospital
2013
Azienda Ospedaliero Universitaria San Giovanni Battista
2013
University of Turin
2013
Nightingale Hospital
2002-2013
University Medical Center Utrecht
2012
Centro Cardiologico Monzino
2012
Rationale: Coronavirus disease (COVID-19) is an ongoing pandemic, in which obesity, hypertension, and diabetes have been linked to poor outcomes. Obstructive sleep apnea (OSA) associated with these conditions may influence the prognosis of adults COVID-19. Objectives: To determine effect OSA on clinical outcomes patients Methods: The current prospective observational study was conducted three hospitals Istanbul, Turkey from March 10 June 22, 2020. participants were categorized as high-risk...
<i>Objectives:</i> We investigated right ventricular (RV) structural and functional cardiac alterations in obstructive sleep apnea (OSA) independent of systemic hypertension their correlation to the severity OSA. <i>Methods:</i> Forty-one moderate-to-severe OSA but otherwise healthy patients 30 body mass index-matched control subjects were included. All underwent 24-hour ambulatory blood pressure monitoring, standard tissue Doppler imaging RV....
Right ventricular systolic pressure is crucial for both treatment and prognosis of cardiovascular pulmonary diseases. The proper measurement right depends on an accurate estimation atrial (RAP). There no standard method estimating RAP noninvasively. purpose this study was to compare different noninvasive methods, namely, inferior vena cava (IVC) size inspiratory collapse, tissue Doppler derived E/E' (TV E/E') RAP, their correlation with catheter-based measurements in patients mitral valve...
The aims of this study were to evaluate subclinical regional right ventricular (RV) dysfunction in newly diagnosed obstructive sleep apnea (OSA) patients without systemic and pulmonary arterial (PA) hypertension, correlate OSA severity RV dysfunction, using both velocity vector imaging (VVI)-derived strain tissue Doppler (TDI).The group consisted 27 the control 26 healthy participants. All participants underwent 24-h ambulatory blood pressure monitoring. Peak systolic myocardial velocities,...
Background: The optimal timing of the surgery in asymptomatic severe mitral regurgitation (MR) remains a challenge. aim study is to evaluate subclinical changes LV longitudinal functions by using novel strain imaging technique; velocity vector (VVI); patients with chronic MR. Methods and Results: We studied 54 asymptomatic, nonischemic, MR (56.8 ± 9 years 56% male) 30 healthy controls (55 6.5 55% normal ejection fraction. Patients were analyzed tertiles according their regurgitant volumes...
Mitral annular calcification (MAC) is characterized by degenerative of the mitral valve annulus. Atherosclerosis plays role in progression MAC. Fetuin A inhibitor pathological calcification. In present study, we investigated relationship between MAC and fetuin with carotid intima media thickness (CIMT) endothelial dysfunction.In this observational cross-sectional 40 patients documented on transthoracic echocardiography without were included. All had coronary artery disease (CAD). Endothelial...
Objectives Takayasu's arteritis (TAK) is a chronic, inflammatory, large-vessel vasculitis. In this study we aimed to evaluate vascular endothelial function by brachial ultrasonography and carotid artery intima-media thickness (CIMT) in patients with TAK compared systemic lupus erythematosus (SLE) healthy controls.Methods The included 32 TAK, fulfilling the 1990 Classification Criteria of American College Rheumatology (ACR), 18 classified according 1982 ACR 20 age- sex-matched controls....
Our aim was to evaluate subclinical left ventricular (LV) dysfunction, by two novel echocardiographic techniques, velocity vector imaging (VVI)-derived strain and tissue Doppler (TDI), in patients with asymptomatic, severe aortic regurgitation (AR).Forty AR normal ejection fraction 30 controls were included the study. All underwent a standard echocardiography extended TDI VVI analyses. To LV longitudinal circumferential deformation, segmental systolic peak rate (SRs) data acquired from...
Echocardiographic assessment of patients with mitral valve stenosis (MS) requires a detailed evaluation anatomy, area (MVA), and pressure gradient presence concomitant diseases. Our aim was to evaluate planimetric MVA transmitral flow velocities using cardiac magnetic resonance (CMR) in isolated MS compare transthoracic echocardiography (TTE) determine the reliability.Thirty-one (mean age 50.4 ± 10.2, 90.3% women) who were normal sinus rhythm included study. Patients ejection fraction <50%,...
The aim of the present study was to evaluate pre-existent subclinical mechanical atrial dysfunction in patients with postoperative fibrillation (POAF) by using novel echocardiographic techniques.Ninety-six sinus rhythm, undergoing coronary artery bypass graft (CABG) operation were prospectively enrolled. Preoperative left (LA) reservoir, conduit and booster functions evaluated 3 different methods: conventional echocardiography, tissue Doppler imaging (TDI), 2-dimensional strain...
Behcet's disease (BD) is a chronic inflammatory characterized by recurrent oral and genital ulcerations ocular lesions. This multisystemic disorder primarily affects the vascular system. In present study, we aimed to evaluate endothelial function in patients with Behcet' s without involvement.We studied 40 BD (44.9±5.4 years) 20 healthy controls (45.4±8.2 years). Brachial artery Doppler ultrasonography (USG) bilateral carotid intima-media thickness measurements were performed.Basal diameter...
Background The relationship between cardiovascular diseases and the diurnal blood pressure (BP) rhythm was researched in many studies. It has been demonstrated that nondipping pattern associated with target organ damage worsened outcomes. aim of our study to assess aortic elasticity parameters carotid intima‐media thickness (CIMT) diastolic dysfunction terms “dipper” “nondipper” hypertension subtypes. Methods A total 60 hypertensive patients without known coronary heart disease were...
Increasing prevalence of obesity is a significant problem in Western countries. Obesity has many effects on cardiovascular structure, function, and hemodynamics. Our aim was to compare the impact body mass index (BMI) right ventricular (RV) functions among healthy subjects with conventional echocardiography, tissue Doppler imaging (TDI), velocity vector (VVI).Eighty-one divided into three group according their BMI. All were evaluated by TDI, VVI. A full polysomnogram performed BMI ≥ 30...
Patients with chronic obstructive pulmonary disease (COPD) can develop left ventricular (LV) systolic dysfunction and geometric changes due to several reasons.To investigate subclinical LV structural features in patients COPD, its correlation the severity of airway obstruction, identified by GOLD classification.We studied 52 COPD 29 age sex-matched controls, without any cardiac disease. In addition conventional echocardiographic evaluation speckle tracking echocardiography (STE)-based strain...
Purpose: Right ventricular (RV) function plays an important role in the development of clinical symptoms, exercise capacity, prognosis, and survival patients with mitral stenosis (MS). The purpose this study was to evaluate global regional RV systolic functions using a novel technique, VVI, mild‐to‐moderate MS without symptoms heart failure. Methods: population consisted 60 (mean age 51.7 ± 11.6 years; 85% female) isolated rheumatic valve 40 age‐ sex‐matched control subjects 49.1 10.5 76.7%...
Acquired pseudoaneurysm of the left ventricle is a very rare disorder and mostly occurs after large transmural myocardial infarction (MI) with peak creatine phosphokinase-MB levels greater than 150 IU/mL. Patients developing ventricular (LV) usually present angina or heart failure symptoms. Although different imaging modalities exist, coronary angiography gold standard for diagnosis. Surgery treatment choice LV pseudoaneurysms detected in first months MI. Here we report case 74-year-old...
ABSTRACT Background Lipoprotein(a) [Lp(a)] plasma level is a well‐known risk factor for coronary artery disease (CAD). Existing data regarding the influence of sex on Lp(a)‐CAD relationship are inconsistent. Objective To investigate between Lp(a) and CAD in men women to elucidate any sex‐specific differences that may exist. Methods Data patients with measurements who were admitted tertiary university hospital, Koc University Hospital, analyzed. The levels was explored all subgroups created...
Background Behcet's disease (BD) is a chronic inflammatory characterized by recurrent oral and genital ulcerations ocular lesions. Subclinical cardiac involvement may develop in BD patients. We aimed to evaluate subclinical left ventricular (LV) right (RV) systolic dysfunction patients without any apparent cardiovascular disease. Methods studied 50 (43.8 ± 9.7 years, 59% men) 30 healthy controls (45.4 8.2 60% men). Conventional echocardiography, tissue Doppler imaging, velocity vector...