A5008318241- Epigenetics and DNA Methylation
- Cancer, Lipids, and Metabolism
- Caveolin-1 and cellular processes
- RNA Research and Splicing
- Lipid metabolism and biosynthesis
- Histone Deacetylase Inhibitors Research
- Cancer-related Molecular Pathways
- Cellular Mechanics and Interactions
- Nuclear Structure and Function
- Hedgehog Signaling Pathway Studies
- RNA modifications and cancer
- Genomics and Chromatin Dynamics
- Lipoproteins and Cardiovascular Health
- Prostate Cancer Treatment and Research
- Cellular transport and secretion
- Autophagy in Disease and Therapy
National Institute of Technology Rourkela
2023-2024
Abstract Mechanical forces may be generated within a cell due to tissue stiffness, cytoskeletal reorganization, and the changes (even subtle) in cell's physical surroundings. These of impose mechanical tension intracellular protein network (both cytosolic nuclear). could released by series protein–protein interactions often facilitated membrane lipids, lectins sugar molecules thus generate type signal drive cellular processes, including differentiation, polarity, growth, adhesion, movement,...
Importance of de novo synthesis cholesterol in proliferating GSCs and role Caveolin-1 this scenario is tested. Inhibition biosynthesis by lovastatin; efflux membrane MBCyD implicated that, inhibition has severe effects on through down-regulation Caveolin-1, stem cell marker proteins CD133, CD44, PAX6 alteration cellular metabolism. CAV1 gene down regulation drug-treatment conditions due to reversal active epigenetic mark H3K4me3 inactive H3K4me the promoter region association with elevated...
Liquid-liquid phase separation (LLPS) describes many biochemical processes, including hydrogel formation, in the integrity of macromolecular assemblages and existence membraneless organelles, ribosome, nucleolus, nuclear speckles, paraspeckles, promyelocytic leukemia (PML) bodies, Cajal bodies (all exert crucial roles cellular physiology), evidences are emerging day by day. Also, is well documented generation plasma membrane subdomains interplay between membranous organelles. Intrinsically...