A5066208475- Virus-based gene therapy research
- Animal Virus Infections Studies
- Herpesvirus Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Animal Disease Management and Epidemiology
- Cytomegalovirus and herpesvirus research
- T-cell and Retrovirus Studies
- Parvovirus B19 Infection Studies
- Vector-Borne Animal Diseases
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Immunology Research
- Toxoplasma gondii Research Studies
- Viral Infections and Vectors
- Essential Oils and Antimicrobial Activity
- Viral-associated cancers and disorders
- Vector-borne infectious diseases
- Bartonella species infections research
- Microbial infections and disease research
- Phytochemistry and biological activities of Ficus species
- Congenital Anomalies and Fetal Surgery
- Phytochemistry and Bioactive Compounds
- Rabies epidemiology and control
- Education Pedagogy and Practices
- HIV Research and Treatment
- Virology and Viral Diseases
University of Bari Aldo Moro
2016-2025
San Salvatore Hospital
2015
Rega Institute for Medical Research
2008
GTx (United States)
2005
University of Veterinary Medicine
2002
Parco Nazionale d'Abruzzo
1997
University of Tübingen
1995
Inserm
1995
Kennedy Krieger Institute
1995
University of Missouri
1990-1991
Two isolates of canine parvovirus (CPV) were obtained from dogs affected with severe haemorrhagic diarrhoea. Type 2b antigenic specificity was predicted by both analysis monoclonal antibodies and PCR characterization type-specific primers. Nevertheless, sequence the capsid protein-encoding gene revealed two amino acid changes. One changes position 426 (Asp to Glu), in a major site viral capsid, determining replacement residue unique CPV type 2b. The failure established typing methods...
Abstract Canine coronavirus (CCoV) is usually responsible for mild, self-limiting infections restricted to the enteric tract. We report an outbreak of fatal disease in puppies caused by a pathogenic variant CCoV that was isolated from organs with severe lesions.
The spread of extended-spectrum β-lactamase-producing Escherichia coli and methicillin-resistant Staphylococcus aureus has caused a reduction in antibiotic effectiveness an increase mortality rates. Essential oils (EOs), known for their therapeutic efficacy, can be configured as novel broad-spectrum biocides. Accordingly, the bacteriostatic-bactericidal activity Citrus Lemon (LEO), Pinus Sylvestris (PEO), Foeniculum Vulgaris (FEO), Ocimum Basilicum (BEO), Melissa Officinalis (MEO), Thymus...
Essential oils (EOs) of Cymbopogon citratus and proximus are known as sources monoterpenes sesquiterpenoids, although their biological activities have not been well investigated. In this study, the compositions C. EOs Egyptian origin antifungal antibiofilm properties against Candida spp. Malassezia furfur were Antioxidant also evaluated. GC-MS showed presence nine eight constituents in EOs, respectively, with geranial neral major compounds EO piperitone α-terpinolene EO. Both (MIC values...
ABSTRACT By antigenic and genetic characterization of canine parvovirus type 2 (CPV-2) strains collected in 2001 2002 Italy, it was possible to observe the spread viruses with an unusual mutation, Glu-426, affecting a major epitope CPV-2. Out 67 analyzed, 49 (73.13%) were characterized as CPV-2a, 6 (8.95%) CPV-2b, 12 (17.91%) Glu-426 mutant.
ABSTRACT Canine parvovirus type 2 (CPV2) emerged in 1978 as causative agent of a new disease dogs. New antigenic variants (biotypes), designated CPV2a and CPV2b, became widespread during 1979 to 1980 1984, respectively. At the present time original CPV2 has disappeared dog population been replaced by two viruses. In study comparison neutralizing antibody titers groups pups (18 each group) inoculated with CPV2b modified live virus vaccines is reported. Using hemagglutination inhibition (HI)...
An outbreak of dual infection in dogs with canine adenovirus type 1 (CAV-1) and coronavirus (CCV) is reported an animal shelter that comprised approximately 200 adults stray 30 puppies. Twenty puppies died 7-8 days after the onset clinical signs (severe enteritis, leucopoenia, respiratory distress dehydration). Both CAV-1 CCV were isolated from tissue or swab samples. Antibodies to and, at high levels, also detected several The principal histological findings atrophy small intestinal villi,...
The VP4 gene of a G5 Italian porcine rotavirus strain, 344/04-1, was nontypeable by PCR genotyping. amino acid sequence the full-length protein had low identity (<or=76.6%) with homologous sequences representative strains remaining P genotypes, providing evidence for novel genotype.
ABSTRACT Sixty-nine fecal samples from diarrheic puppies were examined by reverse transcription-PCR assays for the M and S genes of canine coronaviruses (CCoVs). The isolates in 10 recognized as CCoV type I, 6 II, while both genotypes simultaneously detected 53 samples.
Dioscoretine isolated from the aqueous fraction of methanol extract Dioscorea dumetorum tubers when administered intra-peritoneally to normal and alloxan diabetic rabbits produces significant hypoglycaemic effects at a dose 20 mg/kg. The fasting blood sugar in normoglycaemic was reduced 112 mg/100 ml 55 after 4 hours. In rabbits, lowered 520 286 same time interval. produced comparable 100 chloroform raised 196 6 h. acute toxicity studies gave LD50 values 1.4 g/kg for 0.58 dioscoretine tested...
The emergence of colistin-resistant Enterobacteriaceae in food products is a growing concern due to the potential transfer resistance human pathogens. This study aimed assess prevalence raw and ready-to-eat samples collected from two regions Italy (Apulia Basilicata) evaluate their phenotypes genetic characteristics. A total 1000 were screened, with 4.4% Enterobacteriaceae. majority isolates belonged Enterobacter spp. (60%), followed by Moellerella wisconsensis, Atlantibacter hermannii,...
Noroviruses are a major cause of acute gastroenteritis, often transmitted through contaminated food and water. In this study, lemon juice (LJ), rich in citric acid (CA) flavonoids, was tested against Feline Calicivirus (FCV), used as surrogate human norovirus. Significant virucidal activity observed for pure LJ (pH = 2.3), with reduction viral titers high 4.50 log10 TCID50/50 µL after 30 s complete inactivation 1 min. also showed limited at dilution 1:2000 6.7), titer 0.75 µL. CA (at the...