Antonio Filippi

ORCID: 0000-0003-4308-8746
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Research Areas
  • Signaling Pathways in Disease
  • ATP Synthase and ATPases Research
  • Nanoparticles: synthesis and applications
  • Horticultural and Viticultural Research
  • Plant-Microbe Interactions and Immunity
  • Plant Water Relations and Carbon Dynamics
  • Plant responses to water stress
  • Photosynthetic Processes and Mechanisms
  • Water Systems and Optimization
  • Ecology and Vegetation Dynamics Studies
  • Plant Gene Expression Analysis
  • Studies on Chitinases and Chitosanases
  • Mitochondrial Function and Pathology
  • Cassava research and cyanide
  • Phytochemical compounds biological activities
  • Biosensors and Analytical Detection
  • PARP inhibition in cancer therapy
  • Fermentation and Sensory Analysis
  • Water Treatment and Disinfection
  • Aluminum toxicity and tolerance in plants and animals
  • Heat shock proteins research
  • Nanotechnology research and applications
  • Spaceflight effects on biology
  • Cell death mechanisms and regulation
  • Postharvest Quality and Shelf Life Management

University of Udine
2016-2025

The Nutrient Use Efficiency in intensive agriculture is lower than 50% for macronutrients. This feature results unsustainable financial and environmental costs. Nanofertilizers are a promising application of nanotechnology agriculture. use nanofertilizers an efficient safe manner calls knowledge about the actual effects nanoproducts on plant metabolism eventually carrier release kinetics nutrient accumulation. Hydroxyapatite (Ca10(PO4)6(OH)2) nanoparticles (nHA) have interesting potential to...

10.3390/agronomy9040161 article EN cc-by Agronomy 2019-03-27

Engineered nanoscale materials (ENMs) are considered emerging contaminants since they perceived as a potential threat to the environment and human health. The reactions of living organisms when exposed metal nanoparticles (NPs) or NPs different size not well known. Very few studies on NPs-plant interactions have been published, so far. For this reason there is also great concern regarding impact food safety. Early genotoxic phytotoxic effects cerium oxide (nCeO2) titanium dioxide (nTiO2)...

10.3389/fpls.2015.01043 article EN cc-by Frontiers in Plant Science 2015-11-25

Binding of the mitochondrial chaperone TRAP1 to client proteins shapes bioenergetic and proteostatic adaptations cells, but panel clients is only partially defined. Here we show that interacts with F-ATP synthase, protein complex provides most cellular ATP. competes peptidyl-prolyl cis-trans isomerase cyclophilin D (CyPD) for binding oligomycin sensitivity-conferring (OSCP) subunit increasing its catalytic activity counteracting inhibitory effect CyPD. Electrophysiological measurements...

10.1038/s41418-022-01020-0 article EN cc-by Cell Death and Differentiation 2022-05-25

In recent years, biofungicides have drawn increasing interest in vineyards for a more sustainable integrated and copper-limited pest management. Among alternatives, botanicals could represent valuable tools, being rich sources of biologically active compounds. Conversely to the well-known antioxidant biological properties relation health benefits, investigation on bioactivity hot pungent Capsicum sp. products against fungal phytopathogens is still scarce. Therefore, present study aimed at...

10.1002/ps.7435 article EN cc-by Pest Management Science 2023-03-03

Abstract Aim Climate warming and increasing human disturbance are expected to promote non‐native plant invasions in mountain ecosystems. Although biological also be modulated by biotic interactions, it is still not clear how invertebrate herbivores can affect invasion dynamics. Using a large manipulative experiment, we aimed at testing: (1) the effect of soil elevation on native communities, (2) plant‐herbivore nitrogen deposition, driving establishment after disturbance. Location European...

10.1111/jbi.14097 article EN Journal of Biogeography 2021-03-25

In grapevine, the anatomy of xylem conduits and non-structural carbohydrates (NSCs) content associated living parenchyma are expected to influence water transport under limitation. fact, both NSC features play a role in plant recovery from drought stress. We evaluated these traits petioles Cabernet Sauvignon (CS) Syrah (SY) cultivars during stress (WS) recovery. CS, response was consumption, supporting hypothesis that starch mobilization is related an increased supply maltose sucrose,...

10.3390/ijms21041457 article EN International Journal of Molecular Sciences 2020-02-20

Abstract The need to minimise the impact of phytosanitary treatments for disease control boosted researchers implement techniques with less environmental impact. development technologies using molecular mechanisms based on modulation metabolism by short dsRNA sequences appears promising. intrinsic fragility polynucleotides and high cost these can be circumvented nanocarriers that protect bioactive molecule enabling efficiency delivery leaf surface extending its half-life. In this work, a...

10.1042/bsr20230817 article EN Bioscience Reports 2023-10-26

ABSTRACT Background We recently demonstrated that following a 10‐day exposure to inactivity/simulated microgravity impairments of oxidative metabolism were located ‘upstream’ mitochondrial function, as evaluated by maximal ADP‐stimulated respiration (JO 2max ) determined ex vivo. The aim this study was evaluate sensitivity submaximal [ADP] an alternative approach aimed at identifying responses associated with fibre type composition. Methods Isolated permeabilized vastus lateralis fibres...

10.1002/jcsm.13775 article EN cc-by Journal of Cachexia Sarcopenia and Muscle 2025-04-25

In striking analogy with Saccharomyces cerevisiae, etiolated pea stem mitochondria did not show appreciable Ca2+ uptake. Only treatment the ionophore ETH129 (which allows electrophoretic equilibration) caused uptake followed by increased inner membrane permeability, depolarization and release. Like permeability transition (PT) of mammals, yeast Drosophila, PT was stimulated diamide phenylarsine oxide inhibited Mg-ADP Mg-ATP, suggesting a common underlying mechanism; yet, plant also displayed...

10.3389/fphys.2018.01626 article EN cc-by Frontiers in Physiology 2018-11-21

Abstract Xylem embolism is one of the possible outcomes decreasing xylem pressure when plants face drought. Recent studies have proposed a role for non-structural carbohydrates (NSCs) in osmotic generation, required refilling embolized conduits. Potted cuttings grapevine Grenache and Barbera, selected their adaptation to different climatic conditions, were subjected drought stress followed by re-irrigation. Stem rate its recovery monitored vivo X-ray micro-computed tomography (micro-CT). The...

10.1093/pcp/pcad066 article EN Plant and Cell Physiology 2023-06-29

Nano-biotechnology is one of the most promising areas in modern nanoscience and technology. In this emerging area research, nanoparticles (NPs) play an important role since large-scale production huge numbers utilization. Gold silver are among extensively studied nanomaterials, they show high stability low chemical reactivity comparison to other metals. They commonly synthesized using toxic reducing agents able reduce metal ions into uncharged NPs and/or energy supplied procedures. The used...

10.1063/1.4997133 article EN AIP conference proceedings 2017-01-01

Abstract The study of morphological and physiological responses shrubs to climate is crucial for the understanding future scenarios regarding change. In this light, studying shrub growth acclimation along an elevation gradient might be insightful. phenolic metabolic pathway represents a powerful tool interpret such processes. South‐Eastern Alps, we investigated relationships between elevation, plant traits ( i.e . age, xylem ring width, annual shoot length), plant–plant interaction cover)...

10.1111/plb.13194 article EN Plant Biology 2020-10-10

In the present study, an antibody raised against a peptide sequence of rat bilitranslocase (anti-peptide Ab) was tested on microsomal proteins obtained from red grape berry skin. Previously, this had demonstrated to recognize plant membrane associated with flavonoid binding and transport. Immuno-proteomic assays identified number reacting particular antibody, suggesting that interaction may be extended not only carriers these molecules, but also enzymes very different functions. One is...

10.3390/molecules21101300 article EN cc-by Molecules 2016-09-28

The reduction of synthetic chemistry use in modern viticulture relies on either the biological control microorganisms or induction pathogenesis-related proteins. In present study, effects hydro-alcoholic plant extracts (PEs) (i.e., by-products Vitis vinifera L., leaves Olea europaea L. and Ailanthus altissima (Mill.) Swingle) were tested purified enzymes activity involved plant-pathogen interactions. polyphenolic composition was assayed analyzed to characterize extract profiles. addition,...

10.3390/ijms20246357 article EN International Journal of Molecular Sciences 2019-12-17

Flavonoids represent one of the most important molecules plant secondary metabolism, playing many different biochemical and physiological roles. Although their essential role in life human health has been elucidated by studies, subcellular transport accumulation tissues remains unclear. This is due to absence a convenient simple method monitor transport. In present work, we suggest an assay able follow vivo quercetin, abundant flavonoid tissues. uptake was monitored using...

10.1016/j.fob.2015.08.009 article EN FEBS Open Bio 2015-01-01

Abstract Plant roots are exposed to hypoxia in waterlogged soils, and they further challenged by specific phytotoxins produced microorganisms such conditions. One toxin is hexanoic acid (HxA), which, at toxic levels, causes a strong decline root O 2 consumption. However, the mechanism underlying this process still unknown. We treated pea ( Pisum sativum L.) with 20 mM HxA pH 5.0 6.0 for short time (1 h) measured leakage of key electrolytes as metal cations, malate, citrate nonstructural...

10.1111/ppl.14024 article EN cc-by-nc-nd Physiologia Plantarum 2023-08-01

Hemp (Cannabis sativa L.) for industrial use is often considered as a renewable resource cultivation in polluted areas, on one hand, the purpose of possible remediation soil and, other wide options plant material after harvest such namely hemp fiber. This study summarizes effects landfill leachate irrigation agronomic parameters and fiber properties two cultivars has grown harvested consecutive seasons. Cultivar Bialobrzeskie shows more promising results terms total content phloem content,...

10.1080/15440478.2020.1843101 article EN Journal of Natural Fibers 2020-11-15

10.1016/j.bbabio.2016.04.162 article EN publisher-specific-oa Biochimica et Biophysica Acta (BBA) - Bioenergetics 2016-06-04

Cyclophilin (CyP) D is a regulator of the mitochondrial F-ATP synthase. Here we report discovery form CyPD lacking first 10 (mouse) or 13 (human) N-terminal residues (ΔN-CyPD), protein region with species-specific features. NMR studies on recombinant human full-length (FL-CyPD) and ΔN-CyPD revealed that N-terminus highly flexible, in contrast rigid globular part. We have studied interactions FL synthase at OSCP subunit, site where binding inhibits catalysis favors transition enzyme complex...

10.1038/s42003-024-07172-8 article EN cc-by-nc-nd Communications Biology 2024-11-11
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