Kian Meng Lim

ORCID: 0000-0003-4311-9223
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About
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Research Areas
  • Acoustic Wave Phenomena Research
  • Noise Effects and Management
  • Microfluidic and Bio-sensing Technologies
  • Hearing Loss and Rehabilitation
  • Aerodynamics and Acoustics in Jet Flows
  • Numerical methods in engineering
  • Electronic Packaging and Soldering Technologies
  • Electrostatics and Colloid Interactions
  • Microfluidic and Capillary Electrophoresis Applications
  • Lattice Boltzmann Simulation Studies
  • Vehicle Noise and Vibration Control
  • Electromagnetic Scattering and Analysis
  • Fluid Dynamics and Vibration Analysis
  • Electromagnetic Simulation and Numerical Methods
  • Fluid Dynamics Simulations and Interactions
  • Underwater Acoustics Research
  • Vibration and Dynamic Analysis
  • Enzyme Structure and Function
  • Hearing, Cochlea, Tinnitus, Genetics
  • Fatigue and fracture mechanics
  • 3D IC and TSV technologies
  • Fluid Dynamics and Turbulent Flows
  • Aerospace Engineering and Energy Systems
  • Geotechnical Engineering and Underground Structures
  • Composite Structure Analysis and Optimization

Agency for Science, Technology and Research
2025

National University of Singapore
2015-2024

Robert Bosch (Germany)
2023

University of Regensburg
2023

Environmental Energy & Engineering
2023

Suzhou Research Institute
2014-2019

Singapore-MIT Alliance for Research and Technology
2006-2014

University of Kentucky
2009

Zhejiang University
2007

The University of Sydney
2006

We present a systematic, multiscale, fully detailed numerical modeling for dynamics of fluid flow and ion transport covering Ohmic, limiting, overlimiting current regimes in conductance ion-selective membrane. By numerically solving the Poisson-Nernst-Planck-Navier-Stokes equations, it is demonstrated that electroconvective instability, arising from electric field acting upon extended space charge layer, induced strong vortical are dominant factors planar membrane system. More importantly,...

10.1103/physreve.86.046310 article EN Physical Review E 2012-10-11

Near-infrared (NIR)-to-visible upconversion fluorescent nanoparticles were synthesized and used for imaging targeted delivery of small interfering RNA (siRNA) to cancer cells. Silica-coated NaYF(4) (UCNs) co-doped with lanthanide ions (Yb/Er) synthesized. Folic acid anti-Her2 antibody conjugated UCNs fluorescently label the folate receptors HT-29 cells Her2 SK-BR-3 cells, respectively. The intracellular uptake folic was visualized using a confocal fluorescence microscope equipped an NIR...

10.1088/0957-4484/20/15/155101 article EN Nanotechnology 2009-03-24

We consider electroconvective fluid flows initiated by ion concentration polarization (ICP) under pressure-driven shear flow, a scenario often found in many electrochemical devices and systems. Combining scaling analysis, experiment, numerical modeling, we reveal unique behaviors of ICP flow: unidirectional vortex structure, its height selection, advection. Determined both the external pressure gradient electric body force, dimensionless sheared is shown to scale as...

10.1103/physrevlett.110.114501 article EN publisher-specific-oa Physical Review Letters 2013-03-12

Measurements of mechanical properties biological cells are great importance because changes in these can be strongly associated with the progression cell differentiation and diseases. Although state art methods, such as atomic force microscopy, optical tweezers micropipette aspiration, have been widely used to measure cells, all methods involve direct contact measurements could affected by or any local deformation. In addition, typically deduced Young's modulus based on their measurements....

10.1039/c1lc20687g article EN Lab on a Chip 2011-01-01

In this paper, a new dielectrophoresis (DEP) method based on capture voltage spectrum is proposed for measuring dielectric properties of biological cells. The can be obtained from the balance dielectrophoretic force and Stokes drag acting cell in microfluidic device with fluid flow strip electrodes. was demonstrated measurement human colon cancer cells (HT-29 cells). From spectrum, real part Clausius-Mossotti factor HT-29 different frequencies applied electric field obtained. interior plasma...

10.1063/1.3690470 article EN Biomicrofluidics 2012-03-01

With noises being omnipresent in the modern society, sound-insulating materials are implemented almost all walks of life. For implementations practical applications, those that air-ventilating and mechanically robust highly sought-after. Herein, we present a novel concept using lattice structures as potential ventilated structural materials. Focusing on superimposed tubular plate morphology, defined geometrical factor, wide range elastic properties can be achieved. isotropic consisting three...

10.1016/j.matdes.2023.112354 article EN cc-by-nc-nd Materials & Design 2023-09-25

In this paper, we introduce a dielectrophoresis (DEP)-based separation method that allows for tunable multiplex of particles. traditional DEP separations where the field is applied continuously, size-based particles uses cubic dependence force on particle radius, causing large to be retained while small are released. Here show by pulsing in time, able reverse order (eluting retaining ones), and even extract mid-size from heterogeneous population one step. The operation reminiscent prior...

10.1039/b906202e article EN Lab on a Chip 2009-01-01

Acoustic radiation force can be used to move micro-sized particles, such as cells, in microfluidic devices. Although the number of particles a device is large, typically 2.5% (weight/volume), acoustic acting on particle commonly calculated using an analytical formula for single infinite medium. The interparticle forces are ignored these not easily accounted and with simple closed-form solutions. Based isothermal theory ideal fluid, numerical scheme hereby proposed calculate total force,...

10.1121/1.4916968 article EN The Journal of the Acoustical Society of America 2015-05-01

Drawing on the driving mechanism of biological muscles and combining nonlinear hyperelastic characteristics silicone rubber, a multi-degree-of-freedom pneumatic soft bionic actuator is designed, which can be used as executing for robots robotic arms. Using response surface analysis numerical simulation algorithms, optimal combination structural dimensions parameters determined with maximum bending torsion angles output by optimization objectives. Based idea flexible Piecewise Constant...

10.1080/15376494.2024.2385022 article EN Mechanics of Advanced Materials and Structures 2024-08-01

This paper deals with the mechanics and physics of board-level drop test intention providing fundamental understanding required to design analyse results a test. Three finite element analyses were performed understand failure in impact: (i) velocity impact PCB - modeled as beam; (ii) centrally mounted package (iii) assembly solid elements submodeling. Parametric studies have been on model for number variables: height, fall plate thickness, length, solder bump size, number, cone diameter....

10.1109/eptc.2002.1185692 article EN 2003-08-27
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