- Cardiac, Anesthesia and Surgical Outcomes
- Hernia repair and management
- Gallbladder and Bile Duct Disorders
- Topic Modeling
- Pelvic and Acetabular Injuries
- Sepsis Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Abdominal Surgery and Complications
- Cardiac electrophysiology and arrhythmias
- Pituitary Gland Disorders and Treatments
- Radiology practices and education
- Pelvic floor disorders treatments
- Health Systems, Economic Evaluations, Quality of Life
- Artificial Intelligence in Healthcare and Education
- Hip and Femur Fractures
- Cholangiocarcinoma and Gallbladder Cancer Studies
- ECG Monitoring and Analysis
- Appendicitis Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Venous Thromboembolism Diagnosis and Management
- Patient Safety and Medication Errors
- Vascular anomalies and interventions
- Aortic Disease and Treatment Approaches
- Trauma Management and Diagnosis
- Case Reports on Hematomas
University of Pittsburgh
2018-2024
University of Pittsburgh Medical Center
2016-2024
VA Pittsburgh Healthcare System
2024
Society of Thoracic Surgeons
2022
Dartmouth–Hitchcock Medical Center
2019
American Association for the Surgery of Trauma
2019
Jackson Memorial Hospital
2019
University of Mississippi Medical Center
2019
University of Rochester
2008-2011
University of Rochester Medical Center
2008
Rapid source control is recommended to improve patient outcomes in sepsis. Yet there are few data guide how rapidly required.To determine the association between time and community-acquired sepsis.Multihospital integrated health care system cohort study of hospitalized adults (January 1, 2013, December 31, 2017) with sepsis as defined by Sepsis-3 who underwent procedures. Follow-up continued through January 2019, analyses were completed March 17, 2022.Early (<6 hours) compared late (6-36...
Thorough QT (TQT) studies are designed to evaluate potential effect of a novel drug on the ventricular repolarization process heart using QTc prolongation as surrogate marker for torsades de pointes. The current measure intervals from thousands electrocardiograms is lengthy and expensive. In this study, we propose validation highly automatic-QT interval measurement (HA-QT) method. We applied HA-QT method data 7 TQT studies. investigated both placebo baseline-adjusted induced by moxifloxacin...
Abstract Background Despite advances in natural language processing (NLP), extracting information from clinical text is expensive. Interactive tools that are capable of easing the construction, review, and revision NLP models can reduce this cost improve utility reports for secondary use. Objectives We present design implementation an interactive tool identifying incidental findings radiology reports, along with a user study evaluating performance usability tool. Methods Expert reviewers...
Objective: The aim of the study was to quantify risk incarceration incisional hernias. Background: Operative repair is definitive treatment for ventral hernias but often deferred if perceived elective operation elevated secondary comorbid conditions. during nonoperative management (NOM) factors into shared decision making by patient and surgeon; however, incidence acute remains largely unknown. Methods: A retrospective analysis adult patients with an International Classification Diseases,...
Objective: Our objective was to assess potential racial bias within the Risk Analysis Index (RAI). Background: Patient risk measures are rarely tested for bias. Measures of frailty, like RAI, need be evaluated poor predictive performance among Black patients. Methods: Retrospective cohort study using April 2010–March 2019 Veterans Affairs Surgical Quality Improvement Program and 2010–2019 National data. The RAI several variants were compared between White cases various metrics predict...
The use of hepatitis C virus-positive (HCV+) donors has expanded the donor pool for orthotopic heart transplantation (OHT). This study evaluated center-level trends and utilization HCV+ OHT.Data were extracted from Scientific Registry Transplant Recipients on adults (≥18 y) undergoing OHT between January 1, 2016 December 31, 2019. Centers performing <10 OHTs during period excluded. Donor rates at center level. Center-level characteristics compared centers virus-negative (HCV-) recipient...
BACKGROUND The significance of pneumatosis intestinalis (PI) remains challenging. While certain clinical scenarios are predictive transmural ischemia, risk models to assess the presence pathologic PI needed. aim this study was determine what patient factors at time radiographic diagnosis predict for PI. METHODS We conducted a retrospective cohort examining patients with from 2010 2016 multicenter hospital network. Multivariate logistic regression used develop model in derivation cohort....
BACKGROUND Acute incisional hernia incarceration is associated with high morbidity and mortality yet there little evidence to guide which patients will benefit most from prophylactic repair. We explored baseline computed tomography (CT) characteristics incarceration. METHODS A case-control study design was utilized explore adults (≥18 years) diagnosed an between 2010 2017 at a single institution 1-year minimum follow-up. Computed imaging the time of initial diagnosis examined. Following...
Objectives There is limited literature regarding outcomes after sacrocolpopexy mesh removal. We sought to compare the proportion of prolapse recurrence in women removal with who underwent without subsequent hypothesize that more will experience Methods This a retrospective cohort study between 2010 and 2019. These patients were time matched had but did not undergo Prolapse was defined as leading edge past hymen or retreatment. Analysis done using χ 2 , Wilcoxon rank-sum, t test Cox...
Medical intensive care unit (MICU) patients develop acute surgical processes that require operative intervention. There are limited data addressing outcomes of emergency general surgery (EGS) in this population. The aim our study was to characterize the breadth consults from MICU and assess mortality after abdominal EGS cases.All with an consult academic medical center between January 2010 2016 were identified electronic record-based registry. Charts reviewed determine reason for consult,...
In this study, we investigated the ability of a QT algorithm to detect small drug-induced interval prolongation by adopting "highly-automatized" approach. set 8,911 digital ECGs, analyzed drug-concentration profile computerized QTc measurements submitted Food and Drug Administration (FDA) pharmaceutical companies. The RR intervals were measured using lead II based on included in COMPAS software package developed at University Rochester Medical Center, NY. When comparing time-dependent effect...
Laparoscopic cholecystectomy is the most common abdominal operation performed in United States. Although rates of biliary injury are low, they remain twice that an open cholecystectomy. The infundibular-first approach to a laparoscopic method for removing gallbladder. It has visual advantages compared top-down approach, however there inherent error traps can be unavoidable with this technique. We propose semi-top-down technique while keeping safety approach.
Tibial vein thrombosis after ultrasound-guided foam sclerotherapy (USGS) is an uncommon but recognized complication, the clinical significance of these provoked deep thromboses (DVTs) remains unclear and current management varies considerably. Our group sought to characterize behavior tibial DVTs UGFS across all treatment modalities, including anticoagulation (AC), antiplatelet therapy, or observation only, hypothesizing no significant difference in between three groups.