Pauline Dianne Santos

ORCID: 0000-0003-4324-5967
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About
Contact & Profiles
Research Areas
  • Viral Infections and Vectors
  • Virology and Viral Diseases
  • Mosquito-borne diseases and control
  • Rabies epidemiology and control
  • Salmonella and Campylobacter epidemiology
  • Aquaculture disease management and microbiota
  • COVID-19 diagnosis using AI
  • Maternal Mental Health During Pregnancy and Postpartum
  • Viral gastroenteritis research and epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • Insect symbiosis and bacterial influences
  • Parasite Biology and Host Interactions
  • Animal Disease Management and Epidemiology
  • Wastewater Treatment and Reuse
  • Water Treatment and Disinfection
  • Free Radicals and Antioxidants
  • Vibrio bacteria research studies
  • Fecal contamination and water quality
  • Biological Activity of Diterpenoids and Biflavonoids
  • Plant-based Medicinal Research
  • Global Maternal and Child Health
  • COVID-19 Impact on Reproduction
  • Viral Infections and Outbreaks Research
  • Zoonotic diseases and public health
  • COVID-19 Clinical Research Studies

Friedrich-Loeffler-Institut
2020-2025

University of Uyo
2024

New York State Department of Health
2022

University of the Philippines Diliman
2017-2020

One year after the first autochthonous transmission of West Nile virus (WNV) to birds and horses in Germany, an epizootic emergence WNV was again observed 2019. The number infected considerably higher compared 2018 (12 birds, two horses), resulting observation epidemy Germany: 76 cases 36 five confirmed mosquito-borne, human cases. We demonstrated that Germany experienced several introduction events strains a distinct group (Eastern German clade), which introduced as single event, dominated...

10.3390/v12040448 article EN cc-by Viruses 2020-04-15

The emergence of West Nile virus (WNV) and Usutu (USUV) in Europe resulted significant outbreaks leading to avifauna mortality human infections. Both viruses have overlapping geographical, host vector ranges, are often co-circulating Europe. In Germany, a nationwide bird surveillance network was established monitor these zoonotic arthropod-borne migratory resident birds. this framework, co-infections with WNV USUV were detected six dead birds collected 2018 2019. Genomic sequencing...

10.1111/tbed.14050 article EN Transboundary and Emerging Diseases 2021-03-03

Phytol (3,7,11,15-tetramethylhexadec-2-en-1-ol; PHY), the alcoholic diterpenoid is particularly interesting due to its diverse activities found in literature. This study evaluated vitro and vivo antioxidant capacity of PHY.We conducted DPPH• (2,2-diphenyl-1-picrylhydrazyl) ABTS•+ (2,2'-azino-bis(3- ethylbenzthiazoline-6-sulphonic acid)) radical scavenging tests as vitro, while Saccharomyces cerevisiae test vivo. For tests, trolox for hydrogen peroxide (H2O2) were taken standard...

10.2174/1389201017666161019155715 article EN Current Pharmaceutical Biotechnology 2016-11-03

This study aimed to detect Salmonella from retail meat collected nine wet markets in Metro Manila, and identify the subtypes of isolates using molecular serotyping assays previously developed primers. Of 720 samples, 57.64% were found be Salmonella-contaminated. The most predominant serogroup was O:3, serogroups O:4, O:6,7, O:8, O:9, undetermined also found. Most frequently detected bovine S. 3:e,h:1,6 (putative identity: Anatum) S: 4:e,h:1,2 Saintpaul), porcine Anatum), 8:i:z6 Kentucky)...

10.1371/journal.pone.0239457 article EN cc-by PLoS ONE 2020-09-30

Abstract Background Multiple reports have described neonatal SARS‐CoV‐2 infection, including likely in utero transmission and early postnatal but published estimates of infection range by geography design type. Objectives To describe maternal, pregnancy characteristics among neonates born to people with during testing results. Methods Using aggregated data from the Surveillance for Emerging Threats Mothers Babies Network (SET‐NET) describing infections 20 January 2020 31 December 2020, we...

10.1111/ppe.12883 article EN Paediatric and Perinatal Epidemiology 2022-04-18

Mammalian orthobornaviruses, such as Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1, are zoonotic pathogens that cause fatal encephalitis in humans. BoDV-2, another mammalian orthobornavirus with high genetic homology to BoDV-1, is believed share the same geographical distribution indicating its potential risk human health. However, due limited number of isolations, virological characteristics pathogenicity infectivity, remain largely unexplored. Here, we re-evaluated...

10.1038/s44298-025-00117-w article EN cc-by-nc-nd npj Viruses 2025-04-17

West Nile virus (WNV) is the most widespread arthropod-borne (arbo) and primary cause of arboviral encephalitis globally. Members WNV species genetically diverged are classified into different hierarchical groups below rank. However, demarcation criteria for allocating sequences these remain individual inconsistent, use names levels unstructured. In order to have an objective comprehensible grouping sequences, we developed advanced workflow using 'affinity propagation clustering' algorithm...

10.1093/ve/vead013 article EN cc-by Virus Evolution 2023-01-01

Utilizing molecular methods for monitoring and determining water quality in developing countries can be problematic. Effective extraction storage of DNA from environmental samples is especially difficult due to lack access sufficient laboratory facilities work. Use a commercial product the DNA, as well its application microbial surface waters, was evaluated compared. Surface collected Chao Phraya River Thailand were processed enumerate Escherichia coli. Quantification done through culture...

10.55455/jmesr.2024.001 article EN Journal of Materials & Environmental Sustainability Research 2024-03-12

Abstract Proactive approaches in preventing future epidemics include pathogen discovery prior to their emergence human and/or animal populations. Playing an important role discovery, high-throughput sequencing (HTS) enables the characterization of microbial and viral genetic diversity within a given sample. In particular, metagenomic HTS allows unbiased taxonomic profiling sequences; hence, it can identify novel highly divergent pathogens such as viruses. Newly discovered sequences must be...

10.1093/ve/veab085 article EN cc-by Virus Evolution 2021-09-23

Abstract West Nile virus (WNV) is the most widespread arthropod-borne (arbo) and primary cause of arboviral encephalitis globally. Members WNV species genetically diverged are classified into different hierarchical groups below rank. However, demarcation criteria for allocating sequences these remain individual, inconsistent, use names levels unstructured. In order to have an objective comprehensible grouping sequences, we developed advanced workflow using “affinity propagation...

10.1101/2022.10.05.509209 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-10-07

Abstract Viruses belonging to the genus Orthobornavirus within family Bornaviridae are known infect various vertebrate species, including mammals and birds. Within genus, species bornaense includes two mammalian viruses: Borna disease virus 1 (BoDV-1), prototype of family, its closely related virus, BoDV-2. BoDV-1 was identified as causative agent (BD) in horses, sheep, humans, other mammals. BoDV-2 first detected a pony eastern Austria 1999 that exhibited severe incurable neurological...

10.1101/2024.04.15.589485 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-04-15

<title>Abstract</title> Borna disease virus 1 (BoDV-1) is the causative agent of disease, a progressive and mostly fatal neurologic disorder domestic mammals humans, resulting from spill-over infection its natural reservoir host, bicolored white-toothed shrew (Crocidura leucodon). The known BoDV-1 endemic area remarkably restricted to parts Germany, Austria, Switzerland Principality Liechtenstein. To gain comprehensive data on occurrence BoDV-1, we analysed diagnostic material suspected...

10.21203/rs.3.rs-3640627/v1 preprint EN cc-by Research Square (Research Square) 2023-11-29

Abstract Aplectana hylambatis (Baylis, 1927) is a widespread nematode in South America that infects different species of anurans from families. Although the morphology this shows intraspecific variations and well studied, A. does not have genetic characterisation. Therefore, present study aimed to provide first characterisation parasite, based on 18S 28S rDNA sequences, as evaluate its phylogenetic position family Cosmocercidae. The specimens showed no major morphological were assigned...

10.1017/s0022149x24000609 article EN Journal of Helminthology 2024-01-01
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