J. Andrés Fernández-Sarmiento

ORCID: 0000-0003-4337-7062
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About
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Research Areas
  • Veterinary Pharmacology and Anesthesia
  • Anesthesia and Sedative Agents
  • Anesthesia and Pain Management
  • Periodontal Regeneration and Treatments
  • Hemodynamic Monitoring and Therapy
  • Tendon Structure and Treatment
  • Knee injuries and reconstruction techniques
  • Shoulder Injury and Treatment
  • Antibiotics Pharmacokinetics and Efficacy
  • Pediatric Pain Management Techniques
  • Osteoarthritis Treatment and Mechanisms
  • Sports injuries and prevention
  • Nursing care and research
  • Non-Invasive Vital Sign Monitoring
  • Single-cell and spatial transcriptomics
  • Historical and Modern Theater Studies
  • Organ Transplantation Techniques and Outcomes
  • Trace Elements in Health
  • Neurogenetic and Muscular Disorders Research
  • Comparative Literary Analysis and Criticism
  • Tissue Engineering and Regenerative Medicine
  • Medical research and treatments
  • Diabetic Foot Ulcer Assessment and Management
  • Cancer Cells and Metastasis
  • Connective tissue disorders research

University of Córdoba
2014-2023

Cordoba University
2022

Background: The use of plasma rich in growth factors (PRGF) has been proposed to improve the healing Achilles tendon injuries, but there is debate about effectiveness this therapy. objective present study was evaluate histological effects PRGF, which a type leukocyte-poor platelet-rich plasma, on healing. Methods: tendons twenty-eight sheep were divided surgically. animals randomly into four groups seven each. repaired two received an infiltration PRGF intraoperatively and every week for...

10.2106/jbjs.k.01659 article EN Journal of Bone and Joint Surgery 2013-02-06

Ten New Zealand White rabbits were used in a crossover experimental study: 200 µg/kg medetomidine and 1 (M1) or 2 mg/kg (M2) morphine administered intramuscularly. After preoxygenation, anaesthesia was induced with alfaxalone at 10 intravenously. The trachea intubated 60 per cent oxygen provided. Heart respiratory rates (HR RR), direct arterial pressures (APs), pH (pHa), PaO , PaCO SaO taken baseline, after premedication every minutes during the 90 following induction. times to return ear...

10.1136/vr.101293 article EN Veterinary Record 2014-01-01

Abstract Purpose Articular cartilage is vulnerable to multiple types of damage and it has limited reparative regenerative capacities due its absence vascularity. Although a large number therapeutic strategies exist treat chondral defects, they have some limitations, such as fibrocartilage formation. Therefore, the goal present study was evaluate chondrogenic properties an autologous-made matrix particulated platelet-rich plasma (PACI + PRP) implantation for treatment full-thickness defects...

10.1007/s00167-022-07295-7 article EN cc-by Knee Surgery Sports Traumatology Arthroscopy 2023-01-04

A prospective, randomised, blinded controlled study was performed to determine the anaesthetic and cardiorespiratory effects of a constant‐rate infusion (CRI) alfaxalone in 12 sheep anaesthetised with desflurane, undergoing experimental orthopaedic surgery. Sheep were sedated dexmedetomidine (4 μg/kg, intravenously) butorphanol (0.3 mg/kg, intravenously). Anaesthesia induced (1 mg/kg/minute effect, maintained desflurane oxygen 0.07 or saline for 150 minutes (range 150–166 minutes). The...

10.1136/vr.100487 article EN Veterinary Record 2012-07-12

Abstract Objective To (1) evaluate lithium dilution (LiDCO) and transpulmonary thermodilution (PiCCO TD ) in relation to traditional (PAC‐TD) for determining cardiac output (CO) 3 different hemodynamic states dogs (2) compare the continuous CO values obtained using power analysis (PulseCO) with PiCCO (PiCCOc). Design Prospective randomized study. Setting University research laboratory. Animals Fourteen healthy Beagles. Interventions was measured PAC‐TD, LiDCO, induced random order defined on...

10.1111/vec.12219 article EN Journal of Veterinary Emergency and Critical Care 2014-08-20

This study aimed to determine the performance of averaged parasympathetic tone activity (PTAm) and its dynamic variation (ΔPTA) assess intraoperative nociception in relation heart rate (HR) direct mean arterial pressure (MAP) dogs undergoing laparoscopic ovariectomy. prospective, observational, clinical included 32 bitches. The PTAm, HR, MAP, bispectral index (BIS) were assessed before (pre-stimulus), as well 1 min 2 after, four surgical stimuli: insufflation, introduction trocars, removal...

10.1080/01652176.2023.2239311 article EN cc-by-nc Veterinary Quarterly 2023-07-19

Liquid biopsy based on the analysis of circulating cell-free DNA (cfDNA), as well detection point mutations by digital droplet PCR (ddPCR), has revolutionized research in oncology. In recent years, this technique been pioneering veterinary medicine since it is a minimally invasive approach with very promising results for characterization tumors.The aim study was, firstly, to analyze concentration and fragmentation pattern cfDNA dogs mammary tumors (n = 36) healthy 5) its correlation...

10.3389/fvets.2023.1157878 article EN cc-by Frontiers in Veterinary Science 2023-03-29

ObjectiveTo assess the effect of continuous wound infusion (CWI) with preperitoneal ropivacaine on postoperative analgesia and compare it epidural administration morphine in bitches undergoing ovariohysterectomy.Study designA parallel, randomized, clinical, prospective nonblinded study.AnimalsA group 38 Greyhound bitches.MethodsIn catheter (CathG), CWI 1% (1 mg kg–1 + 0.8 hour–1) was applied to space over surgical incision. In (EpiG), 0.5% (1.3 kg–1) (0.1 were epidurally administered....

10.1016/j.vaa.2021.04.009 article EN cc-by Veterinary Anaesthesia and Analgesia 2021-07-23

This study performs an analysis that will enable the evaluation of quality, durability, and structure repaired cartilaginous extracellular matrix tissue using autologous-based particulated autograft cartilage platelet-rich plasma treatment (PACI + PRP). A single-blind controlled experiment was conducted on 28 sheep to evaluate efficacy PACI PRP for defects. Full-thickness 8 mm diameter defects were created in weight-bearing area both knees. The right knees received PRP. left treated with...

10.3390/ijms242015157 article EN International Journal of Molecular Sciences 2023-10-13

Tendon injuries are the most frequent musculoskeletal problems, constituting 30–50% of all sport-related lesions. Efficient handling early stage tendon injury and healing can accelerate repair as well improve quality newly formed tendons. Plasma rich in growth factors (PRGF) is an autologous biological therapy that has been proposed to treat injuries. To elucidate effect this treatment on healing, 14 sheep were used perform present study. The right Achilles was surgically severed repaired...

10.1080/09712119.2017.1337017 article EN cc-by Journal of Applied Animal Research 2017-06-07

Abstract Objective To evaluate the use of gastric (PgCO 2 ) and bladder (PbCO tonometry for assessing tissue hypoperfusion in dogs during sevoflurane‐induced hypotension, to compare these measurements with delivery oxygen, arterial oxygen content, plasma lactate concentration. Design Prospective experimental trial. Setting University veterinary teaching hospital. Animals Fourteen adult Beagle dogs. Interventions Anesthetic induction was performed by mask sevoflurane oxygen. Heart rate,...

10.1111/vec.12642 article EN Journal of Veterinary Emergency and Critical Care 2017-08-14

Abstract The purpose of this study was to perform a histological and biochemical evaluation the influence plasma rich in growth factors (PRGF) on muscle regeneration process after surgically induced grade II laceration. A randomized, single blind, controlled experimental research conducted including twenty-one adult healthy sheep, randomly divided three groups (n = 7). surgical section performed biceps femoris both hindlimbs. After two days (basal time), intralesional infiltration autologous...

10.1186/s12917-022-03491-2 article EN cc-by BMC Veterinary Research 2022-11-12

Abstract Background Intestinal ischemia-reperfusion (IR) is an important clinical occurrence seen in common diseases, such as gastric dilatation-volvulus dogs or colic horses. Limited data available on the use of methylene blue veterinary medicine for intestinal ischemia-reperfusion. The present study aimed to compare hemodynamic, histopathological, and immunohistochemical effects two doses rabbit model groups In one group, 5 mg/kg IV was administered, another, 20 administered following a...

10.1186/s12917-020-02279-6 article EN cc-by BMC Veterinary Research 2020-02-12
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