A5075252869- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Plant-Microbe Interactions and Immunity
- Plant Pathogens and Fungal Diseases
- Studies on Chitinases and Chitosanases
- Catalysis for Biomass Conversion
- Mesoporous Materials and Catalysis
- Adsorption and biosorption for pollutant removal
Instituto Venezolano de Investigaciones Científicas
2012-2021
The fungal genus Sporothrix includes at least four human pathogenic species. One of these species, S. brasiliensis, is the causal agent a major ongoing zoonotic outbreak sporotrichosis in Brazil. Elsewhere, sapronoses are caused by schenckii and globosa. aims on this comparative genomic study are: 1) to explore presence virulence factors brasiliensis; 2) compare which cat-transmitted infects both humans cats with schenckii, mainly pathogen; 3) two species other pathogens (Onygenales) similar...
Sporotrichosis is a subcutaneous mycosis caused by pathogenic species of the Sporothrix genus. A new emerging species, brasiliensis, related to cat-transmitted sporotrichosis and has severe clinical manifestations. The cell wall fungi unique structure impacts directly on host immune response. We reveal compare structures schenckii S. brasiliensis using high-pressure freezing electron microscopy study organization both species. To analyze components wall, we also used infrared 13C 1H NMR...
Sporothrix schenckii , brasiliensis and globosa are the main causative agents of sporotrichosis, a human subcutaneous mycosis. Differences in virulence patterns associated with each species but remain largely uncharacterized. The S. cell wall composition influenced by culturing media, little or no influence on . By keeping constant we compared three two strains, previously described as presenting different levels murine model infection. five spp. strains correlated biochemical reported for...
α-1,3-Glucan is present as the outermost layer of cell wall in pathogenic yeastlike (Y) form Paracoccidioides brasiliensis. Based on experimental evidence, this polysaccharide has been proposed a fungal virulence factor. To degrade α-1,3-glucan and allow remodeling wall, α-1,3-glucanase required. Therefore, study enzyme, its encoding gene, regulatory mechanisms, might be interest to understand morphogenesis process fungus. A single orthologous other genes, was identified genome, labeled...