A novel Fourier domain fast scanning optical delay line is proposed in which the walk-off eliminated by only two passes through a diffraction grating. Working transmission, ideal for balanced coherence tomography configurations with recirculation of reference beam. We evaluate theoretically and experimentally its dispersion compensation capabilities.

Owing to the limited spectral response of fiber directional coupler used in a balanced optical coherence tomography configuration, spectra are different two outputs. This affects unfavorably operation photodetector unit. Excess photon noise makes larger contribution than with flat response. A theoretical model is developed that shows an optimum set parameters may be defined maximize achievable signal-to-noise ratio. The leads redefinition effective bandwidth, which takes into account nonflat...

Recent trends on microbiology point out the urge to develop optical micro-tools with multifunctionalities such as simultaneous manipulation and sensing. Considering that miniaturization has been recognized one of most important paradigms emerging sensing biotechnologies, fiber tools, including Optical Fiber Tweezers (OFTs), are suitable candidates for developing multifunctional small sensors Medicine Biology. OFTs flexible versatile optotools based fibers extremity patterned form a...

Extreme Learning Machines (ELMs) are a versatile Machine (ML) algorithm that features as the main advantage possibility of seamless implementation with physical systems. Yet, despite success implementations ELMs, there is still lack fundamental understanding in regard to their optical implementations. In this context, work makes use an complex media and wavefront shaping techniques implement ELM playground gain deeper insight into these machines. particular, we present experimental evidences...

Abstract A scheme for the simultaneous determination of temperature and analyte concentration application in luminescence-based chemical sensors is proposed. This applied to an optical oxygen sensor, which based on quenching fluorescence a ruthenium complex. Temperature measurement performed using excitation radiation absorption long-pass filter. Preliminary results are presented that show viability independent power level. The possibility self-referenced measurements with semiconductor...

A versatile time-domain optical coherence tomography system is presented that can generate cross-sectional images by using either transverse priority or depth scanning. This made possible a transmissive scanning delay line compatible with balance detection operating at speed similar to of the scanner used scan beam across target. In vivo from retina are generated and shown same switched regime, in slow fast modes, respectively. comparative analysis different regimes depending on image size...

Optical coherence tomography (OCT) systems have huge potential for applications beyond the traditional ophthalmology as a general-purpose medical instrument optical biopsy. The widening of range is expected to significantly increase production volume and, consequently, puts pressure on unit cost. This trend calls flexible and miniaturized system fabricated in batch process. In this paper, different OCT configurations are compared suitability such an implementation. required flexibility...

In view of the growing importance nanotechnologies, detection/identification nanoparticles type has been considered utmost importance. Although characterization synthetic/organic is currently a priority (eg, drug delivery devices, nanotextiles, theranostic nanoparticles), there are many examples "naturally" generated nanostructures - for example, extracellular vesicles (EVs), lipoproteins, and virus that provide useful information about human physiology or clinical conditions. For detection...

The ability to select, isolate, and manipulate micron-sized particles or small clusters has made optical tweezers one of the emergent tools for modern biotechnology. In conventional setups, classification trapped specimen is usually achieved through acquired image, scattered signal, additional information such as Raman spectroscopy. this work, we propose a solution that uses temporal data signal from scattering process trapping laser, with quadrant photodetector. Our methodology rests on...

We derive the time-variant second-order statistics of depth-scan photocurrent in time-domain optical coherence tomography (TD-OCT) systems using polarized thermal light sources and superluminescent diodes (SLDs). Since asymptotic-joint-probability-distribution function (JPDF) due to is Gaussian signal-noise-ratio TD-OCT typically high (>80 dB), JPDF could be approximated as a random process that completely determined by its statistics. analyze both direct differential detection schemes...

Immunosensors can play an important role in the improvement of public health by providing applications for which rapid detection, high sensitivity, and specificity are important, areas such as clinical chemistry, food quality, environmental monitoring. The standard immunoassay techniques basis development improved automated devices, exploring accumulated know how implementation indirect detection methods during last 40 years. Todaýs systems achieve accuracy, specificity, sample throughput....

High-precision dosimeters are needed in brachytherapy treatments to ensure safe operation and adequate working conditions, assess the correspondence between treatment planning dose delivery, as well monitor radiation received by patients. In this paper we present development of a multi-sensor dosimeter platform targeted for environments. The performance different scintillating materials response is assessed. emission bands most common scintillator used ionizing detection typically below 550...

A spectral calibration technique, a data processing method and the importance of re-sampling methods for domain optical coherence tomography system were numerically studied, targeted to (OCT) signal implementation under graphics unit (GPU) architecture. Accurately, assigning wavelength each pixel detector is paramount obtain high quality images increase noise ratio (SNR). High imaging can be achieved by proper methods, here performed phase interpolation. SNR was assessed employing two...

Optical Tweezers (OT) are able to trap/manipulate dielectric particles with few microns in a contactless manner due forces exerted on them by strongly focused optical beam. OT being applied Biology/Medicine, especially Fiber (OFT), for simpler and more flexible than the conventional setups. Despite of trapping phenomena symmetrical OFTs already modeled, effects regarding complex bodies remain poorly understood. Here we provide 2D characterization laser OFT geometric form Red Blood Cell...

A computational method for optical fiber trapping of healthy and Malaria-infected blood cells characterization is proposed. force relation with the infection stage was found, which could trigger development a diagnostic sensor.

An optical fiber sensor for the measurement of oxygen in gaseous environments, which is based on quenching fluorescence a ruthenium complex, presented. The sensing chemistry immobilized sol-gel solid matrix that coated tapered probe. Oxygen performed both by phae and intensity spectroscopy. Experimental results show lifetime depend temperature. A scheme simultaneous determination temperature concentration proposed. Temperature using excitation radiation an absorption long pass filter....

Femtosecond Titanium:sapphire lasers can deliver high average power broadband spectra in a quality beam, being therefore an optical source of choice for high-resolution coherence tomography (OCT) at acquisition rates. We present brief tutorial on the basic physics behind operation and design Kerr-lens modelocked lasers, where peak powers associated with femtosecond pulses give rise to nonlinear effects that play major role laser itself strongly influence output spectrum. Additional devices,...

Optical Tweezers (OTs) have been widely applied in Biology, due to their outstanding focusing abilities, which make them able exert forces on micro-sized particles. The magnitude of such (pN) is strong enough trap targets. However, the most conventional OT setups are based complex configurations, being associated with difficulties biologic samples. Fiber (OFTs), consist optical fibers a lens one its extremities valuable alternatives Conventional (COTs). OFTs flexible, simpler, low-cost and...