A5078867526- Aquaculture disease management and microbiota
- AI in cancer detection
- Veterinary Oncology Research
- Animal Virus Infections Studies
- Parasite Biology and Host Interactions
- Myxozoan Parasites in Aquatic Species
- Radiomics and Machine Learning in Medical Imaging
- Mycobacterium research and diagnosis
- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Fibroblast Growth Factor Research
- Herpesvirus Infections and Treatments
- Cancer, Hypoxia, and Metabolism
- Microbial infections and disease research
- Marine Ecology and Invasive Species
- Cancer and Skin Lesions
- Infectious Diseases and Mycology
- Metabolism, Diabetes, and Cancer
- dental development and anomalies
- Vibrio bacteria research studies
- Viral Infections and Immunology Research
- Food Supply Chain Traceability
- Monoclonal and Polyclonal Antibodies Research
- Zoonotic diseases and public health
- Fish Ecology and Management Studies
University of Sassari
2015-2024
The integration of digitalization and Artificial Intelligence (AI) has marked the onset a new era efficient sheep farming in multiple aspects ranging from general well-being to advanced web-based management applications. resultant improvement health consequently better yield already started benefit both farmers veterinarians. predictive analytical models embedded with machine learning (giving sense machines) helped decision-making enabled derive most out their farms. This is evident ability...
Canine mammary tumors (CMTs) represent a serious issue in worldwide veterinary practice and several risk factors are variably implicated the biology of CMTs. The present study examines relationship between histological diagnosis large CMT dataset from three academic institutions by classical statistical analysis supervised machine learning methods. Epidemiological, clinical, histopathological data 1866 CMTs were included. Dogs with malignant significantly older than dogs benign (9.6 versus...
Canine mammary tumors (CMTs) share many features with human breast cancer (HBC), specifically concerning cancer-related pathways. Although the epidermal growth factor receptor 2 (HER2) plays a significant role as therapeutic and prognostic biomarker in HBC, its relevance pathogenesis prognosis of CMT is still controversial. The aim this study was to investigate HER2 expression canine hyperplasic neoplastic tissues well evaluate specificity most commonly used polyclonal anti antibody by...
Histopathology, the gold-standard technique in classifying canine mammary tumors (CMTs), is a time-consuming process, affected by high inter-observer variability. Digital (DP) and Computer-aided pathology (CAD) are emergent fields that will improve overall classification accuracy. In this study, ability of CAD systems to distinguish benign from malignant CMTs has been explored on dataset-namely CMTD-of 1056 hematoxylin eosin JPEG images 20 24 CMTs, with three different based combination...
Hemostatic alterations have been documented in dogs with canine parvoviral enteritis. This study’s aims were to measure the standard coagulation parameters, and assess relationship between them clinical variables Nine client-owned a infection included prospective, observational study. Clinical score status assessed at admission. All nine showed of three or more variables. A correlation analysis evidenced significantly high positive activated partial thromboplastin time score. The present...
Mycobacterium marinum is a slow-growing non-tuberculous mycobacterium, and it considered the most common aetiologic agent of mycobacteriosis in wild cultured fish. The diagnosis principally made by histology when positive Ziehl-Neelsen stain granulomas are detected. aim this study was to investigate occurrence extensively Mugilidae two lagoons (Cabras San Teodoro) from Sardinia use histology, microbiology, PCR DNA sequencing. Nine 106 mullets examined were affected mycobacteriosis, spleen...
In recent years, research on fish has seen remarkable advancements, especially in aquaculture, ornamental industry, and biomedical studies. Immunohistochemistry become crucial research, aiding physiological pathological investigations. However, the use of antibodies originally developed for mammals raised concerns about their cross-reactivity specificity fish. This study systematically evaluated reactivity commonly used diagnostic purposes, pathology, including pan-cytokeratin, vimentin,...
The family Papillomaviridae includes a plethora of viral species infecting virtually all vertebrates excluding amphibians, with astonishing impact on human and animal health. Although more than 250 have been described in humans, the total number papillomaviruses (PVs) discovered animals does not reach up to this number. In animals, PV infections are mostly asymptomatic or can cause variable clinical conditions ranging from self-limiting papillomas other cutaneous mucosal benign lesions...
Canine mammary tumors represent the most common neoplasm in female dogs, and discovery of cancer biomarkers their translation to clinical relevant assays is a key requirement war on cancer. Since description 'Warburg effect', reprogramming metabolic pathways considered hallmark pathological changes cells. In this study, we investigate expression two cancer-related enzymes, transketolase (TKT) transketolase-like 1 (TKTL1), involved pentose phosphate pathway (PPP), an alternative for glucose...
Consumer preference for healthy and sustainable food products has been steadily increasing in recent years. Bivalve mollusks satisfy these characteristics have captured ever-increasing market shares. However, the expansion of molluscan culture worldwide global trade favored spread pathogens around world. Combined with environmental changes intensive production systems this contributed to occurrence mass mortality episodes, thus posing a threat different species, including Pacific oyster...
The first case of infection Streptococcus iniae in Adriatic sturgeon (Acipenser naccarii) was recently reported a raceway system located Northern Italy. A second episode sturgeons with absence mortality and evident clinical signs, registered November 2020 the same farm is this study. Histopathological changes observed infected organs are described. strains isolated two episodes were compared using molecular analysis based on PCR, phylogeny virulence factors analysis. Not all major detected...
The term intersex describes alterations in gonadal development with the simultaneous presence of male and female reproductive stages same gonad a gonochoristic species. In coastal estuarine environments, euryhaline fish living polluted waters such as Mugilidae can frequently show these sexual anomalies. this work, we analysed adult specimens three species mullets (Chelon labrosus, Liza aurata Mugil cephalus) from two Sardinian lagoons (Marceddì San Teodoro) devoted to extensive aquacultural...
Abstract The dusky grouper Epinephelus marginatus (Lowe) is an ecologically and commercially important fish species of the Atlantic Mediterranean coastal rocky habitats. Despite records didymozoid infections in several species, identification pathogenesis these parasites E. are lacking. aim this study to characterize didymozoids , particularly their mechanisms infection histopathological features. Dusky groupers ( n = 205) were caught off Majorca Island (western Sea) examined for parasites....
Porcine respiratory disease complex (PRDC) represents a significant threat to the swine industry, causing economic losses in pigs worldwide. Recently, beyond endemic viruses PRRSV and PCV2, emerging such as TTSuV, PCV3, PPV2, have been associated with PRDC, but their role remains unclear. This study investigates presence of PCV2 (PCV3, PPV2) lungs belonging different age groups by histopathology real-time PCR. The prevalent lung lesion was interstitial pneumonia increased severity...
Histozoic parasite–fish host interaction is a dynamic process that leads to the formation of granuloma, specific chronic inflammatory response with discernible histological features. Mullets (Osteichthyes: Mugilidae) represent suitable model concerning development such lesions in host–parasite interface. The present work aimed identify granuloma developmental stages from early late phase infection and characterize immune cells non-inflammatory components different stages. For this purpose,...
Skin tumors with adnexal differentiation are commonly reported in dogs and cats, while only anecdotal evidence is available sheep. Here we illustrate the macroscopic, histologic, immunohistochemical features of a cutaneous lesion 6-year-old female Sarda breed sheep, surgically treated for horn-like mass located left pinna. Additionally, investigate possible contribution Ovine Papillomaviruses (OaPVs). Histologically, dermis was expanded by an expansive unencapsulated multilobulated nodule...
The microcotylid Sparicotyle chrysophrii is one of the most harmful parasites for aquaculture gilthead seabream Sparus aurata , which effective treatments are needed. efficacy dietary praziquantel (PZQ, 30–50 mg kg body weight −1 day ), emamectin benzoate (EMB, 0.015–0.050 BW and fenbendazole (FBZ, 40–75 ) against S. on was tested in four different vivo challenge trials. Specimens naturally infected with were maintained three separate recirculating systems 142 L (1 control vs. 2 treated)....
Meagre (Argyrosomus regius) is one of the fast-growing species considered for sustainable aquaculture development along Mediterranean and Eastern Atlantic coasts. The emergence Systemic Granulomatosis (SG), a disease marked by multiple granulomas in various tissues, poses significant challenge meagre aquaculture. In current study, we investigate association Mycobacterium spp. SG offshore facilities Sardinia, Italy. A total 34 adult seemingly healthy were arbitrarily collected analyzed,...