A gold catalyzed enantioselective [3+2] dipolar cycloaddition of N-allenyl amides with nitrones was developed to give chiral 4-alkylidenyl isoxazolidine derivatives in high yields and excellent enantioselectivities by using BINOL derived phosphoramidate Au(I) catalysts.

Gold(I) catalyzed [3+2] cycloaddition of azomethine imines with N-allenyl amides was developed to provide two types pyrazolyl based bicyclic heterocycles. Both pyrazolidin-3-one derived and dihydroisoquinoline reacted smoothly give 6-methylene bipyrazolidin-1-ones 1-methylene hexahydropyrazolo[5,1-a] isoquinolines in moderate good yields.

Ring-opening polymerization (ROP) is a powerful approach to prepare well-defined polymers. Herein, one-component Lewis pair strategy was adopted, and two delicate pairs 1–2 were rationally designed conveniently synthesized. featured an electropositive phosphonium cation, electrophilic boron centers involving 9-borabicyclo[3.3.1]nonane moieties, nucleophilic halide (Br– or I–). 1–2-mediated ROP of propylene oxide (PO) exhibited activity (turnover frequency = 3600 h–1) with living...

Abstract Hydrogen‐bond mediated coupling of 1,2,3‐triazoles to indoles and pyrroles results in N2 selective functionalization the triazole moiety moderate excellent yields. The reaction was tolerant un‐, mono‐ disubstituted triazoles applied synthesize tryptophan derived fluorescent amino acids.

A new tandem allylation/enyne cycloisomerization reaction was developed to construct densely functionalized oxygen hetereocycles with high diastereoselectivities from the intermolecular of allylic acetates propargylic alcohols via gold catalysis. Terminal and nonterminal take different routes either provide 3-oxa-bicyclo[4.1.0]hept-4-ene derivatives 5 or give endocyclic rearrangement products 7 alkoxycyclization adducts 8. Cyclopropane's stereochemistry mainly determined by substituents.

A new method was developed to synthesize iodine-substituted <italic>Z</italic>-enamides through <italic>N</italic>-iodosuccinimide-mediated intermolecular iodofunctionalization of allenamides with indoles, pyrroles, and furans.

Organic selenium compounds are important molecules with a wide range of applications in pharmaceuticals, organic materials, catalysis, and other fields. Herein, we report the synthesis α-selenomethylketones through reaction vinyl azides arylselenols benzylselenol. This protocol has advantages releasing only nitrogen as benign byproduct, using air an environmentally friendly initiator, very short duration, mild conditions, broad substrate compatibility. The results exploratory studies show...

The first report of NIS-promoted two-step radical addition thiols to allenamides provide an efficient route for accessing 1,3-dithioethers.

A new efficient method was developed to transform cyclic alkanols into one-carbon higher homologated ketones using various esters as the leaving groups through gold-catalyzed allylic cation-promoted pinacol-type rearrangement. This reaction, coupled with oxy-Cope rearrangement, provided a strategy synthesize five-carbon ring ketones. In addition, ZnBr(2), 2,5-dihydrofuran products were obtained in moderate good yields via an intramolecular cyclization process.

A N1-selective alkenylation of 1-sulfonyl-1,2,3-triazoles with alkynes via gold catalysis is reported. N1-Vinyl substituted 1,2,3-triazoles were selectively prepared in up to 92% yield through the sulfonyl group 1,2,3-triazole derivatives transformed alkenyl groups a "one-pot two steps" manner. This method provided new for synthesis potentially biological-active vinyl-triazole building blocks.

The first report of iron catalyzed azidation allenamides <italic>via</italic> radical process to provide an efficient route for accessing allyl azides.

We report a new protocol to synthesize allylic <italic>N</italic>,<italic>N</italic>-acetal derivatives through NIS-mediated hydroamination of allenamides with imidazole heterocycles.

An efficient new method was developed to synthesis <italic>N</italic>-2-alkyl-1,2,3-trizoles <italic>via</italic> gold catalyzed alkylation of 1-sulfonyl-1,2,3-trizoles with vinyl ethers.

An efficient new method was developed for the synthesis of 2-halo allylic aminal derivatives through regioselective 1,2-addition allenamides with<italic>N</italic>-haloimides.

A new method was developed to synthesize N²-alkyl-substituted 1,2,3-triazoles <italic>via</italic> gold catalyzed alkylation of vinyl ethers with mono- and unsubstituted NH-1,2,3-triazoles benzotriazole.

We report a new protocol to synthesize <italic>N</italic>²-allyl-substituted 1,2,3-triazoles <italic>via</italic> NIS mediated allylation of allenamides with <italic>NH</italic>-1,2,3-triazoles.

The first example of gold-catalyzed formal intermolecular [4 + 2 1] cycloaddition was developed using 1,3-dien-8-yne as C4 and C2 units diazo ester the C1 unit, which provides expedient access to a series structurally complicated [5.3.0] bicyclic adducts in moderate yields with high diastereoselectivities. key route involved cascade process dienyne cycloisomerization, cyclopropyl gold carbene's trapping, subsequent divinyl cyclopropane (DVCP) Cope rearrangement.

Abstract A convenient new method was developed to prepare unfused polyaromatic furan derivatives from diynyl‐1,6‐diols through a novel base‐catalyzed cascade 1,3‐H shift/cyclization process. Deuterium experiments were performed determine that the shift rate‐determining step.

A catalyst-free intermolecular addition of indoles, pyrroles, and imidazole to allenamides is reported. The reaction proceeds smoothly provides a series (<italic>E</italic>)-ensulfonamide/enamide derivatives in high yields with excellent regioselectivity.