Cystic fibrosis (CF) has been generally well defined throughout the world although its prevalence is very difficult to ascertain for a number of reasons, including fact that medical/scientific literature and patient registries vary in quality different countries. In present review (1938–2017), we found out higher frequency registered CF patients European Union. This could be due strong clinical awareness greater health facilities. contrast, irregular report from Asian African these...

This clinical trial was conducted on 90 patients, aged 30-70 years, who had heart surgery. The participants were categorized into three groups. Group D received 1 µg/kg intravenous dexmedetomidine in 10 minutes, group L 1.5 mg/kg lidocaine (1%) seconds before intubation, and F 2 fentanyl. vital signs (HR, SBP, DBP, MAP) measured intubation 1st, 3rd, 5th, 10th minutes after intubation. Data analyzed with SPSS 19 software (chi-square, one-way ANOVA, or Kruskal-Wallis). age (P=0.389) gender...

In the last days of December 2019, there were reports a coronavirus spreading from Wuhan, China. The infectious nature virus, along with its transmission methods, caused it to spread very quickly other parts world. Despite severity infection by this virus and respiratory nature, no specific complete treatment has yet been provided. This is why severe acute syndrome (SARS) COV-2 becoming more global threat. major root SARS-Cov-2 through binding spike protein human angiotensin-converting...

The rapid expansion of a novel human infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into pandemic, affecting thousands people world wild. Some patients with 2019 (COVID-19) develop infection, which may progress to distress syndrome, multiple organ failure, and death. Increasing studies indicate that abnormal elevation cytokine levels in response SARS-CoV-2 contribute the pathological process leads mortality COVID-19. Thus, application...

Background: The application of methylprednisolone in ARDS patients has led to a sustained reduction inflammatory plasma cytokines and chemokines recently been used the treatment with SARS-CoV-2 infection. Objectives: In this study, effect on clinical symptoms antioxidant changes COVID-19 investigated. Methods: present moderate severe who required hospitalization were entered into study phase. Then, addition standard treatment, received at dose 250 mg intravenously over three days. Necessary...

Introduction : During cardiopulmonary bypass, oxidative stress happens in the patient's cells due to blood contact with various levels of synthetic materials. It can activate inflammatory process and release factors such as IL-6, CRP, Neutrophils witch may hurt different organs. In recent years, many efforts have been made prevent this type damage, however, no single treatment has proposed reduce risk. Antioxidant substances Thiamine is important cell defense against free oxygen radicals....

Introduction: The activation of bradykinin B1 receptors on endothelial cells in the lung following inflammation is a major cause severity and mortality COVID-19. It has already been shown that bromelain montelukast as two anti-inflammatory agents can be effective controlling this condition. Methods: Patients with novel coronavirus (COVID-19) referred to Masih Daneshvari hospital Tehran were included study after providing full explanations obtaining written consent. All 40 patients moderate...

Background: Healthcare workers must wear masks throughout their shifts, especially those in operating rooms for long periods. Objectives: This study evaluated the effects of wearing N95 on blood and cerebral oxygen saturation levels three hours. Methods: The present case-control enrolled 20 room masks. Their (SaO2), end-tidal carbon dioxide partial pressure (PETCO2), right- left-sided regional (rSO2) were measured beginning (0 h) after one Results: Wearing a mask affected PETCO2, rSO2, pulse...

Background: The use of natural resources, especially medicinal plants, for treating and improving the quality life has roots as far back human history. extensive abilities plants ease access have led to these huge resources in modern medicine. present study focused on reviewing component properties Green Nature Deep Lung Support one products with a source. Furthermore, while examining some plants’ effects viral respiratory infections, scientific bases supporting claims were discussed well....

: Pain is recognized as a deeply personal, psychological, and social sensation, the perception of which influenced by diverse factors. The intensity nature pain vary among individuals, rendering highly personal phenomenon that warrants tailored approaches. Precision medicine therapeutic paradigm grounded in evaluation multiple patient-specific factors, including environmental lifestyle, genetic variations, to determine most suitable treatment approach for each individual. Research indicates...

Abstract Background This study aims to explore the potential of utilizing expression levels cannabinoid receptor 2 (CB2), μ-opioid (MOR), MCP-1, IL-17, IFN-γ, and osteopontin as predictors for severity SARS-CoV-2 infection. The overarching goal is delineate pathogenic mechanisms associated with SARS-CoV-2. Methods Using quantitative Real-time PCR, we analyzed gene CB2 MOR in nasopharynx specimens obtained from patients diagnosed infection, 46 individuals classified having severe symptoms...

Background: Accurate and continuous measurement of arterial blood pressure is crucial in managing patients undergoing cardiac surgery to prevent complications ensure better outcomes. Objectives: This study aimed compare monitoring using non-invasive (CNAP) invasive (IAP) methods after weaning from cardiopulmonary bypass (CPB). Methods: Blood was conducted on 30 referred Dr. Masih Daneshvari Hospital Tehran for coronary artery grafting (CABG) surgery. Measurements were taken every two minutes...

Background: Bleeding management during and after urgent heart surgery is always challenging in patients who are taken anticoagulants especially antiplatelet ones. The present study was conducted with the aim of investigating role intraoperative hemoperfusion active removal Plavix undergoing on-pump CABG surgery. Methods: recruited on underwent All have discontinued consuming less than 36 hours before During cardiopulmonary bypass, set added to circuit done according standard open protocols....

The severity of COVID-19 disease and its mortality may be due to a localized vascular problem owing the activation bradykinin B1 receptors on endothelial cells in lungs that occur following inflammation. Bromelain acts as an anti-inflammatory factor can lower level serum tissues. Patients with novel coronavirus (COVID-19) referred Masih Daneshvari Hospital Tehran were included study after providing full explanations obtaining written consent. 40 patients mild moderate symptoms randomly...

Despite much progress in the field of control and struggle advanced laboratory facilities to support accelerate detection parasitic infections a slew new drugs made but parallel development drug resistance Vector insecticides change human hosts are most common especially developing countries Introduction morphology biology clinical diagnostic methods such essentials that we diagnosis treatment diseases prevent complications assist The aim this article Learn all parasites including worms...

Background: Hesperidin is a secondary metabolite of the flavonoid group. Due to its antioxidant, anti-inflammatory and anti-viral properties, it can be helpful as treatment option for patients with COVID 19.
 Methods: This study was conducted clinical trial in Masih Daneshvari Hospital Tehran. After providing complete explanations obtaining written consent, new coronavirus (COVID-19) were included if they met inclusion criteria. 20 study. Patients then randomly divided into hesperidin...

Organoids are a miniature, simplified version of human organ that produced in three dimensions the laboratory and show true anatomical array. These organelles originate from one or more cells - embryonic stem induced multipotent can organize themselves three-dimensional culture media. The use due to unlimited capacity tissue division regeneration is great promise as therapeutic tool. models be used test drugs before they tested on humans. Lung organoids different types that, like other...