A5017193026- Neonatal and fetal brain pathology
- Infant Development and Preterm Care
- Advanced Neuroimaging Techniques and Applications
- Neonatal Respiratory Health Research
- Infant Health and Development
- Functional Brain Connectivity Studies
- Cerebral Palsy and Movement Disorders
- EEG and Brain-Computer Interfaces
- Family and Disability Support Research
- Fetal and Pediatric Neurological Disorders
Helsinki University Hospital
2017-2025
University of Helsinki
2017-2025
Cognitive development is characterized by the structural and functional maturation of brain. Diffusion-weighted magnetic resonance imaging (dMRI) provides methods investigating brain structure connectivity their correlations with neurocognitive outcome. Our aim was to examine relationship between early visual abilities, white matter structures, later
Children born extremely preterm may have difficulties in response inhibition, but the neural basis of such problems is unknown. We recorded magnetoencephalography (MEG) during a somatosensory Go/NoGo task six-year-old children (EPT; n = 22) and full term (FT; 21). The received tactile stimuli randomly to their left little (target) index (non-target) finger were instructed squeeze soft toy with opposite hand every time they felt stimulus on finger. Behaviorally, EPT performed worse than FT...
Objective: The aim of this study was to evaluate the ability neonatal neurobehavioral characteristics act as an indicator for later neurodevelopment and neurocognitive performance. Methods: Sixty-six infants born extremely preterm (<28 gestational weeks) were followed until 6.5 years. Neurobehavior at term age assessed by behavior subscale Hammersmith Neonatal Neurological Examination (HNNE) using dichotomic rating, optimal, non-optimal. Griffiths Mental Developmental Scales (GMDS) 2...
Analysis of scalar maps obtained by diffusion tensor imaging (DTI) produce valuable information about the microstructure brain white matter. The DTI scanning child populations, compared with adult groups, requires specifically designed data acquisition protocols that take into consideration trade-off between time, strength, number directions, and applied analysis techniques. Furthermore, inadequate normalization images non-robust reconstruction have profound effects on analyses may biased...
This study investigated minor impairments in neurological, sensorimotor, and neuropsychological functioning extremely preterm-born (EPT) children compared to term-born children. The aim was explore the most affected domains visualize their co-occurrences relationship maps.A prospective cohort of 56 EPT (35 boys) 37 controls (19 were assessed at a median age 6 years 7 months with Touwen Neurological Examination, Movement Assessment Battery for Children, 2nd edition (MABC-2), Sensory...
We assessed in extremely preterm born (EPB) children whether secondary somatosensory cortex (SII) responses recorded with magnetoencephalography (MEG) at term-equivalent age (TEA) correlate neurodevelopmental outcome 6 years. Secondly, we SII differ between 6-year-old EPB and term-born (TB) children.39 underwent MEG tactile stimulation TEA. At years, 32 26 TB including a sensorimotor task requiring attention motor inhibition. to were modeled equivalent current dipoles. Neurological outcome,...
Cognitive development is characterized by the structural and functional maturation of brain, a cascade where few basic abilities are foundation later cognition. Diffusion-weighted magnetic resonance imaging (dMRI) provides methods to investigate brain structure connectivity their correlations with neurocognitive outcome. Early visual important for development. Therefore, our aim was examine relationship between early abilities, white matter structures, outcome social cognition skills.This...