- Oil Palm Production and Sustainability
- Microbial Community Ecology and Physiology
- Plant Molecular Biology Research
- Helminth infection and control
- Plant Parasitism and Resistance
- Coccidia and coccidiosis research
- Parasitic Infections and Diagnostics
- Genomics and Phylogenetic Studies
- Plant tissue culture and regeneration
- Polar Research and Ecology
- Chromosomal and Genetic Variations
- Plant and animal studies
- Light effects on plants
- Cryospheric studies and observations
- Antioxidant Activity and Oxidative Stress
- Microbial Natural Products and Biosynthesis
- Mycobacterium research and diagnosis
- Plant biochemistry and biosynthesis
- Biochemical Analysis and Sensing Techniques
- Helicobacter pylori-related gastroenterology studies
- Advanced Chemical Sensor Technologies
- Animal Genetics and Reproduction
- Plant Gene Expression Analysis
- Protist diversity and phylogeny
- Soil Carbon and Nitrogen Dynamics
Malaysia Genome Institute
2011-2021
National Institutes of Biotechnology Malaysia
2020
Ministry of Science, Technology and Innovation
2020
Malaysian Palm Oil Board
2008-2019
National University of Malaysia
2008-2012
The cytosolic mevalonate (MVA) pathway in Hevea brasiliensis latex is the conventionally accepted which provides isopentenyl diphosphate (IPP) for cis-polyisoprene (rubber) biosynthesis. However, plastidic 2-C-methyl-D-erythritol 4-phosphate (MEP) may be an alternative source of IPP since its more recent discovery plants. Quantitative RT-PCR (qRT-PCR) expression profiles genes from both pathways showed that subcellular compartmentalization synthesis related to degree carotenoid synthesis....
Abstract Background Oil palm ( Elaeis guineensis Jacq.) is one of the most important oil bearing crops in world. However, genetic improvement through conventional breeding extremely slow and costly, as cycle can take up to 10 years. This has brought about interest vegetative propagation palm. Since introduction tissue culture 1970s, clonal proven be useful, not only producing uniform planting materials, but also development engineering programme. Despite considerable progress improving...
Extremely low temperatures present various challenges to life that include ice formation and effects on metabolic capacity. Psyhcrophilic microorganisms typically have an array of mechanisms enable survival in cold temperatures. In this study, we sequenced analysed the genome a psychrophilic yeast isolated Antarctic region, Glaciozyma antarctica. The annotation identified 7857 protein coding sequences. From sequence analysis were able identify genes encoded for proteins known be associated...
Abstract Background Eimeria is a genus of parasites in the same phylum (Apicomplexa) as human such Toxoplasma , Cryptosporidium and malaria parasite Plasmodium. As an apicomplexan whose life-cycle involves single host, convenient model for understanding this group organisms. Although genomes Apicomplexa are diverse, that unique being composed large alternating blocks sequence with very different characteristics - arrangement seen no other organism. This has impeded efforts to fully genome...
Rafflesia possesses unique biological features and known primarily for producing the world's largest existing as a single flower. However, to date, little is about key regulators participating in flower development. In order further understand molecular mechanism that regulates cantleyi development, RNA-seq data from three developmental stages of floral bud, representing organ primordia initiation, differentiation, bud outgrowth, were analysed. A total 89,890 transcripts assembled which up...
Soil ecosystems are home to a diverse range of microorganisms, but they only partially understood because no single-cell sequencing or whole-community provides complete picture these complex communities. Using one such metagenomics approaches, we succeeded in monitoring the microbial diversity and stress-response gene soil samples. This study aims test whether known differences taxonomic composition reflected functional profiles by implementing whole (WGS) metagenomic analysis geographically...
ABSTRACT Helicobacter pylori is the main bacterial causative agent of gastroduodenal disorders and a risk factor for gastric adenocarcinoma mucosa-associated lymphoid tissue (MALT) lymphoma. The draft genomes 10 closely related H. isolates from multiracial Malaysian population will provide an insight into genetic diversity in Southeast Asia. These were cultured biopsy samples patients with functional dyspepsia cancer. availability this genomic information opportunity examining evolution...
Rafflesia cantleyi, known as one of the world's largest flowers, is a specialised holoparasite due to dramatic morphological modifications. It possesses highly reduced vegetative structure and only appears flower for sexual reproduction. Moreover, it has an unusual life cycle in that its floral bud development takes up nine months. In order fully understand modified organ long R. we used Illumina sequencing technology (HiSeq) sequence generation followed by de novo assembly reads. We...
Abstract Rafflesia is a unique plant species existing as single flower and produces the largest in world. While buds take up to 21 months develop, its flowers bloom wither within about week. In this study, transcriptome analysis was carried out shed light on molecular mechanism of senescence . A total 53.3 million high quality reads were obtained from two cantleyi developmental stages assembled generate 64,152 unigenes. Analysis dataset showed that 5,166 unigenes differentially expressed,...
Taste perception is an essential function that provides valuable dietary and sensory information, which crucial for the survival of animals. Studies into evolution sweet taste receptor gene (TAS1R2) are scarce, especially Bornean endemic primates such as Nasalis larvatus (proboscis monkey), Pongo pygmaeus (Bornean orangutan), Hylobates muelleri (Muller’s gibbon). Primates perfect taxa to study they diverse feeders, comprising specialist folivores, frugivores, gummivores, herbivores,...