It is anticipated that as the range of drugs for which pharmacogenetic testing becomes available expands, primary care physicians (PCPs) will become major users these tests. To assess their training, familiarity, and attitudes toward in order to identify barriers uptake may be addressed at this early stage test use, we conducted a national survey sample PCPs. Respondents were mostly white (79%), based primarily community-based (81%) almost evenly divided between family medicine internal...

Background: Variable health literacy and genetic knowledge may pose significant challenges to engaging the general public in personal genomics, specifically with respect promoting risk comprehension healthy behaviors. Methods: We are conducting a multistage study of individual responses genomic information for Type 2 diabetes mellitus. A total 300 individuals were recruited from Durham, North Carolina: 60% self-identified as White; 70% female; 65% have college degree. As part baseline...

The effects of variations in work load (indexed by paid hours) on psychological well-being, cortisol, smoking, and alcohol consumption were examined a sample 71 workers (44 women, 27 men) the retail industry. Measures obtained four occasions over six-month period, assessments ranked individually according to hours past seven days. Job strain (demand/control) job social support evaluated as potential moderators responses. Paid ranged from mean 32.6 48.0 per week, ratings work-home conflict...

With the emergence of electronic medical records and patient portals, patients are increasingly able to access their health records, including laboratory reports. However, reports usually written for clinicians rather than patients, who may not understand much information in report. While several professional guidelines define content test reports, there no inform development a patient-friendly In this Opinion, we consider barriers comprehension lab results suggest options reformat report...

One of the basic questions in early uses pharmacogenetic (PGx) testing revolves around clinical delivery testing. Because multiple health professionals may play a role PGx testing, various models have begun to be studied. We propose that partnership between genetic counselors and pharmacists can assist clinicians comprehensive services. Based on their expert knowledge pharmacokinetics pharmacodynamics, facilitate appropriate application test results adjust medication use as warranted act...

Aim: To investigate patient experiences with pharmacogenetic (PGx) testing. Methods: Patients were offered PGx testing through a study on pharmacist-assisted delivery of and invited to complete pre- post-testing surveys about their experience. Results: Of 63 patients tested, 17 completed the baseline survey (27%). Interest in was mostly impacted by desire inform selection best treatment (n = 13). Seven 12 that follow-up indicated provider discussed test result them. Five understood very or...

Haga SB, O’Daniel JM, Tindall GM, Mills R, Lipkus IM, Agans R. Survey of genetic counselors and clinical geneticists' use attitudes toward pharmacogenetic testing. Pharmacogenetic (PGx) testing aims to improve therapeutic outcomes through tailoring treatment based on a patient's risk for non‐response and/or an adverse event. Given their expertise, geneticists could facilitate the PGx testing; however, preparedness perceived role genetics community is unclear. To assess attitudes,...

Pharmacogenetic testing refers to a type of genetic test predict patient's likelihood experience an adverse event or not respond given drug. Despite revision several labels commonly prescribed drugs regarding the impact variation, use this has been limited in many settings due number factors. In primary care setting, office time as well knowledge and practitioners have likely attributed slow uptake pharmacogenetic testing. This paper provides talking points for physicians discuss with...

To assess feasibility and patient satisfaction with a pharmacist-delivered medication therapy management (MTM) plus pharmacogenetic (PGx) testing service.Thirty patients from cardiology outpatient clinic were enrolled to attend two MTM sessions, undergo PGx complete pre- post-intervention surveys. Outcome measures included duration of clinical application test results, self-reported adherence, recall results perceived value MTM.Overall, very satisfied the service. About half participants...

Abstract The introduction of cell‐free DNA screening has resulted in increased prenatal identification sex chromosome aneuploidies (SCAs). This study aimed to evaluate genetic counselor experiences disclosing SCAs positive or testing results and counselor‐reported parental questions regarding sex, gender, sexual orientation. Forty‐eight counselors completed the survey. When asked quantify their experiences, 97.9% reported a screen result within previous year, 81.3% disclosed diagnostic...

Genetic information, typically communicated in-person by genetic counselors, can be challenging to comprehend; delivery of this information online--as is becoming more common--has the potential increasing these challenges.To address impact mode genomic risk 300 individuals were recruited from general public and randomized receive for type 2 diabetes mellitus a board-certified counselor or online through testing company's website.Participants asked indicate their overall lifetime as reported...

Personalized medicine continues to expand with the development and increasing use of genome-based testing. While these advances present new opportunities for diagnosis risk assessment, they also challenges clinical delivery. Genetic counselors will play an important role in ushering this era testing; however, it warrant a shift from traditional genetic counseling "genomic counseling." This be marked by move reactive testing primarily single-gene diseases proactive multiple complex purpose...

To describe the rationale and design of a pilot program to implement evaluate pharmacogenetic (PGx) testing in primary care setting.Several factors have impeded uptake PGx testing, including lack provider knowledge challenges with operationalizing clinical practice setting.We plan compare two strategies for implementation testing: pharmacist-initiated arm compared physician-initiated arm. Providers both groups will be required attend an introduction seminar. Anticipated results: We...

To investigate provider utilization of pharmacist support in the delivery pharmacogenetic testing a primary care setting.Two clinics within Duke University Health System participated study between December 2012 and July 2013. One clinic was provided with an in-house second had on-call pharmacist.Providers arm consulted for 13 15 cases, or about one every four patients tested compared 7.5 arm. A total 63 tests were ordered, 48 by providers pharmacist-in-house arm.These findings suggest that...

While genetic counselor (GC) utilization of telehealth has increased in recent years, the onset COVID-19 pandemic significantly accelerated adoption for many. We investigated GC experiences with including perceived advantages, disadvantages, and barriers using a one-time online survey GCs who provided direct patient care years. The examined before after COVID-19. made broad comparisons to findings from similar study our research team conducted five years ago. reported an increase over time,...

Abstract Disclosure is the act of sharing a stigmatized identity, and members LGBTQ+ community make decisions related to disclosure multiple times throughout their life. in medical settings can impact perceptions care outcomes for patients; however, little understood about process decision‐making regarding genetic counseling setting. As such, this study aimed explore experiences sessions behaviors. Fifty‐five individuals who attended session 91 counselors completed online surveys. The...

As few patient-friendly resources about pharmacogenetics are currently available, we aimed to create and assess a patient educational video on pharmacogenetic testing. A primary literature review was conducted inform the content format of video. The then created using commercially available animation program pilot tested in focus groups general public by an online survey pharmacists. Emerging themes from indicate desire for appropriate risk contextualization specific examples when testing...