A5059449980- Dysphagia Assessment and Management
- Cardiac Arrest and Resuscitation
- Tracheal and airway disorders
- Airway Management and Intubation Techniques
- Child Nutrition and Feeding Issues
- Esophageal and GI Pathology
- Parkinson's Disease Mechanisms and Treatments
- Voice and Speech Disorders
- Cardiovascular and Diving-Related Complications
- Spaceflight effects on biology
- Respiratory Support and Mechanisms
- Neurological disorders and treatments
- Trauma and Emergency Care Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Emergency and Acute Care Studies
- Genetic Neurodegenerative Diseases
- Disaster Response and Management
- Anesthesia and Neurotoxicity Research
- Metabolism and Genetic Disorders
- Family and Patient Care in Intensive Care Units
- Intensive Care Unit Cognitive Disorders
- Otitis Media and Relapsing Polychondritis
- Biomedical and Chemical Research
- Healthcare Technology and Patient Monitoring
- Injury Epidemiology and Prevention
Klinikum Osnabrück
2022-2025
University of Münster
2011-2025
University Hospital Münster
2013-2024
Klinikum Oldenburg
2020-2024
European Astronaut Centre
2023
Carl von Ossietzky Universität Oldenburg
2021-2022
Klinik und Poliklinik für Neurologie
2010-2021
Klinik Niederrhein
2018-2019
Evangelisches Klinikum Niederrhei
2018-2019
Evangelisches Krankenhaus Bethesda
2018-2019
Abstract Flexible endoscopic evaluation of swallowing (FEES) is one the most important methods for instrumental evaluation. The challenging part examination consists in interpretation various observations encountered during endoscopy and deduction clinical consequences. This review proposes framework an integrated FEES-report that systematically moves from salient findings FEES to more advanced domains such as dysphagia severity, phenotypes impairment pathomechanisms. Validated scales scores...
<b><i>Background:</i></b> Both delayed and premature extubation increase complication rate, the need for tracheostomy (TT), duration of intensive care unit stay, mortality. In this study, we therefore investigated factors associated with primary TT predictors failure (EF) in a sample severely affected ventilated stroke patients. <b><i>Methods:</i></b> One hundred eighty five intubated patients were prospectively analyzed observational study....
Amyotrophic lateral sclerosis (ALS) is a rare disease causing degeneration of the upper and lower motor neuron. Involvement bulbar neurons often results in fast progressive dysphagia. While cortical compensation dysphagia has been previously shown stroke patients, this topic not addressed patients suffering from ALS. In present study, we investigated activation during deglutition two groups ALS with either moderate or severe Whole-head MEG was employed on fourteen sporadic using self-paced...
Introduction: Although patients with Parkinson's disease (PD) often suffer from oropharyngeal dysphagia, knowledge about the underlying pathophysiological mechanisms is limited. Substance P (SP) a localization-independent neurotransmitter of entire nervous system. Reduced levels SP were found in saliva impaired cough reflex and advanced stages PD. The aim study was to investigate PD order gain further insights into pathophysiology PD-related dysphagia evaluate potential as biomarker for...
The aim of our study was to assess if PES before extubation can minimize the failure risk in orally intubated, mechanically ventilated stroke patients at high severe dysphagia. Thirty-two ICU were prospectively enrolled this presenting with a for dysphagia as defined by DEFISS (Determine Extubation Failure In Severe Stroke) score and compared 1:1 retrospective matched patient control group. prospective group received prior extubation. Endpoints need reintubation, swallowing function assessed...
Pallidal neurostimulation is an effective treatment for severe isolated dystonia, but long-term data from clinical trials are lacking. To evaluate efficacy and safety of pallidal in patients with generalized or segmental dystonia. Extension study the prospective multicenter trial (n = 40; July 2002 to May 2004), all received stimulation underwent regular follow-up. The 10-year follow-up 31) included Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) motor disability score, Beck Depression...
Abstract Background Multiple system atrophy (MSA) is a rare neurodegenerative disorder, and its parkinsonian variant can be difficult to delineate from Parkinson's disease (PD). Despite laryngeal dysfunction being associated with decreased life expectancy quality of life, systematic assessments in large cohorts are missing. Objectives The objective this study was systematically assess MSA PD identify symptoms that allow for differentiating PD. Methods Patients probable or possible underwent...
In its early stages multiple system atrophy (MSA), a neurodegenerative movement disorder, can be difficult to differentiate from idiopathic Parkinson's disease (PD), and emphasis has been put on identifying premotor symptoms allow for identification. The occurrence of vegetative in addition motor impairment, such as orthostatic hypotension neurogenic bladder dysfunction, enable the clinical diagnosis advanced disease. Usually with further progression, laryngeal abnormalities become...
Dysphagia is a common complication of critical illness, and many known risk factors are also present in critically ill coronavirus disease 2019 victims.To investigate dysphagia patients with severe 2019.In this case series, we report results dedicated evaluation swallowing function six consecutive, tracheotomized after they had survived acute respiratory distress syndrome were weaned from the respirator.Dysphagia was assessed flexible endoscopic swallowing.Three suffered airway compromise...
Objective Current neuroimaging research on functional disturbances provides growing evidence for objective neuronal correlates of allegedly psychogenic symptoms, thereby shifting the disease concept from a psychological towards neurobiological model. Functional dysphagia is such rare condition, whose pathogenetic mechanism largely unknown. In absence any organic reason patient's persistent swallowing complaints, sensorimotor processing abnormalities involving central neural pathways...
High-quality cardiopulmonary resuscitation (CPR) by laypersons is a key determinant of both outcome and survival for out-of-hospital cardiac arrest. Dispatcher-assisted CPR (telephone-CPR, T-CPR) increases the frequency correctness bystander-CPR but results in prolonged time to first chest compressions. However, it remains unclear whether instructions rescue ventilation and/or compressions should be recommended dispatcher-assisted CPR.The aim this study was evaluate principles T-CPR with...
Early dysphagia screening and appropriate management are recommended by current guidelines to reduce complications case fatality in acute stroke. However, data on the potential benefit of changes care patient outcome limited. Our objective was assess degree implementation determine impact modifications treatment practices disease stroke patients over time.In this prospective register-based study ("Stroke Register Northwestern Germany"), all adult admitted 157 participating hospitals between...
Abstract Dysphagia is frequent in many neurological diseases and gives rise to severe complications such as malnutrition, dehydration aspiration pneumonia. Therefore, early detection management of dysphagia essential can reduce mortality. This study investigated the effect cognitive motor dual-task interference on swallowing healthy participants, effects are reported for other tasks gait speech. 27 participants (17 females; 29.2 ± 4.1 years) were included this prospective examined using...
Abstract Flexible Endoscopic Evaluation of Swallowing (FEES) is one two diagnostic gold standards for pharyngeal dysphagia in Parkinson's disease (PD), however, validated global outcome measures at the patient level are widely lacking. The Dynamic Imaging Grade Toxicity (DIGEST-FEES) represents such an measure but has been primarily head and neck cancer collectives. objective this study was, therefore, to investigate validity DIGEST-FEES patients with PD. Content was evaluated a modified...
Abstract Patients with multiple system atrophy (MSA) frequently experience dysphagia but only few studies analyzed its characteristics. The aim of this study was to describe the swallowing characteristics in these patients using fiberoptic endoscopic evaluation (FEES). In addition, abilities predominantly cerebellar MSA (MSA-C) and parkinsonian (MSA-P) were compared. Twenty-five (16 MSA-P 9 MSA-C) enrolled. Clinical data including age, sex, functional oral intake scale (FOIS) score, body...
Neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody disease (MOGAD) are demyelinating disorders that typically affect the optic nerves spinal cord. However, recent studies have demonstrated various forms of brain involvement indicating encephalitic syndromes, which consequently included in diagnostic criteria for both. Swallowing is processed a distributed network therefore disturbed many neurological diseases. The aim this study was to investigate...