A5060080262- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Esophageal and GI Pathology
- Voice and Speech Disorders
- Parkinson's Disease Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Neurological disorders and treatments
- Venous Thromboembolism Diagnosis and Management
- Child Nutrition and Feeding Issues
- Neurological diseases and metabolism
- Glycogen Storage Diseases and Myoclonus
- Food Allergy and Anaphylaxis Research
- Lysosomal Storage Disorders Research
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Fetal and Pediatric Neurological Disorders
- Brain Metastases and Treatment
- Neurological and metabolic disorders
- Restless Legs Syndrome Research
- Tumors and Oncological Cases
- Tuberous Sclerosis Complex Research
- Public Health and Nutrition
- Gastroesophageal reflux and treatments
- Cerebrovascular and genetic disorders
- Cerebral Venous Sinus Thrombosis
University Hospital Frankfurt
2014-2024
Goethe University Frankfurt
2014-2024
Klinik und Poliklinik für Neurologie
2014
At present, the flexible endoscopic evaluation of swallowing (FEES) is one most commonly used methods for objective assessment swallowing. This multicenter trial prospectively collected data on safety FEES and also assessed impact this procedure clinical dysphagia management.Patients were recruited in 23 hospitals Germany Switzerland from September 2014 to May 2017. Patient characteristics, professional affiliation examiners (physicians or speech language therapists), side-effects...
Dysphagia is a frequent symptom in patients with acute stroke. It associated malnutrition, aspiration and mortality. The identification of early screening parameters for dysphagia promptly leading to professional swallowing examination therefore utmost importance. This study aimed detect easily assessable predictors large cohort ischemic stroke.Our analysis was based on data from prospective in-hospital registry. Patients stroke were included over the course 3 years. scheduled undergo...
Neurogenic dysphagia is one of the most frequent and prognostically relevant neurological deficits in a variety disorders, such as stroke, parkinsonism advanced neuromuscular diseases. Flexible endoscopic evaluation swallowing (FEES) now probably frequently used tool for objective assessment Germany. It allows efficacy safety swallowing, determination appropriate feeding strategies different manoeuvres. The literature furthermore indicates that FEES safe well-tolerated procedure. In spite...
Dysphagia is a common and severe symptom of acute stroke. Although intracerebral hemorrhages (ICHs) account for 10% to 15% all strokes, the occurrence dysphagia in this subtype stroke has not been widely investigated. The aim study was evaluate overall frequency associated lesion locations clinical predictors patients with ICH.Our analysis included 132 ICH. Clinical swallowing assessment performed within 48 hours after admission. All underwent computed tomography imaging. Voxel-based...
The aim of this study is to present the symptoms, diagnosis, and management unilateral sigmoid sinus thrombosis (SST) in a pediatric patient with acute otitis media, as well propose recommendations for its diagnosis treatment. An 11-year-old girl was referred our clinic persistent high fever, headache, otalgia. She had previously been treated local oral antibiotics. A comprehensive evaluation revealed mastoiditis, SST right ear. Blood tests, along imaging studies including CT scan...
Little is known about the frequency and clinical characteristics of neurogenic dysphagia in pontine strokes. In this study, we sought to identify predictors for a cohort patients with isolated infarctions.We included all admitted our department between 2008 2014 having an acute (<48 hours after symptom onset) ischemic stroke pons, as documented by means diffusion-weighted magnetic resonance imaging. Precise infarct localization was stratified according established vascular territories. The...
Abstract Background Removal of a tracheostomy tube in critically ill neurologic patients is critical issue during intensive care treatment, particularly due to severe dysphagia and insufficient airway protection. The “Standardized Endoscopic Evaluation for Tracheostomy Decannulation Critically Ill Neurologic Patients” (SESETD) an objective measure readiness decannulation. This protocol includes the stepwise evaluation secretion management, spontaneous swallowing, laryngeal sensitivity...
Introduction: Ischemic and hemorrhagic strokes in the brainstem cerebellum with injury to functional loop of Guillain-Mollaret triangle (GMT) can trigger a series events that result secondary trans-synaptic neurodegeneration inferior olivary nucleus. In an unknown percentage patients, this leads condition called hypertrophic degeneration (HOD). Characteristic clinical symptoms HOD progress slowly over months consist rhythmic palatal tremor, vertical pendular nystagmus, Holmes tremor upper...
To assess predictive factors for poststroke pneumonia (PSP) in patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO) of the anterior circulation, special regard impact intravenous thrombolysis (IVT) and endovascular treatment (EVT) on risk PSP. As a secondary goal, validity A2DS2, PNEUMONIA, ISAN scores LVO will be determined.Analysis was based consecutive data years 2017 2019 from prospective inpatient registry covering entire federal state Hesse, Germany, using...
Abstract Flexible Endoscopic Evaluation of Swallowing (FEES) is one two diagnostic gold standards for pharyngeal dysphagia in Parkinson's disease (PD), however, validated global outcome measures at the patient level are widely lacking. The Dynamic Imaging Grade Toxicity (DIGEST-FEES) represents such an measure but has been primarily head and neck cancer collectives. objective this study was, therefore, to investigate validity DIGEST-FEES patients with PD. Content was evaluated a modified...
Removal of a tracheostomy tube in critically ill neurologic patients is difficult issue, particularly due to the high incidence oropharyngeal dysphagia. For an objective evaluation decannulation readiness "Standardized Endoscopic Swallowing Evaluation for Tracheostomy Decannulation Critically Ill Neurologic Patients" (SESETD) - stepwise 'secretion management', 'spontaneous swallows' and 'laryngeal sensibility/cough' has been introduced. With recent study detailed data on inter-rater...
Abstract Dysphagia is common in patients with middle cerebral artery (MCA) infarctions and associated malnutrition, pneumonia, mortality. Besides bedside screening tools, brain imaging findings may help to timely identify swallowing disorders. We investigated whether the Alberta stroke program early CT score (ASPECTS) allows for correlation of distinct ischemic lesion patterns dysphagia. prospectively examined 113 consecutive acute MCA infarctions. Fiberoptic endoscopic evaluation (FEES) was...
Swallowing is a complex task, moderated by sophisticated bilateral network including multiple supratentorial regions, the brainstem and cerebellum. To date, conflicting data exist about whether focal lesions to cerebellum are associated with dysphagia. Therefore, aim of study was evaluate dysphagia prevalence, recovery pattern in patients ischaemic cerebellar stroke.
Background: While swallowing disorders are frequent sequela following posterior fossa tumor (PFT) surgery in children, data on dysphagia frequency, severity, and outcome adults lacking. The aim of this study was to investigate before after surgical removal PFT. Additionally, we tried identify clinical predictors for postsurgical disorders. Furthermore, explored the three-month dysphagic patients. Methods: In a cohort patients undergoing PFT surgery, prospectively assessed pre-...
Abstract Background Intragastric botulinum neurotoxin injections (IBNI) are offered off-label in the private medical sector a few European countries as safe and effective weight-loss measure. In February March 2023, an outbreak of iatrogenic botulism occurred several following IBNI treatment Turkey. This case series describes clinical features severe after IBNI. Methods We retrospectively summarize course emergency department intensive care unit interventions ten cases that receiving this...
Dysphagia is a frequent symptom in acute ischemic stroke (AIS). Endovascular treatment (EVT) has become the standard of care for secondary to large vessel occlusion. Although standardized guidelines poststroke dysphagia (PSD) management exist, they do not account this setting which patients receive EVT under general anesthesia. Therefore, aim study was evaluate PSD prevalence and severity, as well an appropriate time point evaluation, undergoing anesthesia (GA).We prospectively included 54...
Abstract Objective Deep brain stimulation (DBS) of the ventral intermediate nucleus (VIM) is a mainstay treatment for severe and drug‐refractory essential tremor (ET). Although stimulation‐induced dysarthria has been extensively described, possible impairment swallowing not systematically investigated yet. Methods Twelve patients with ET bilateral VIM‐DBS self‐reported dysphagia after were included. Swallowing function was assessed clinically using by flexible endoscopic evaluation in...
Dysphagia is a common and severe symptom of traumatic brain injury (TBI) affecting up to 78% patients. It associated with pneumonia, increased morbidity, mortality. Although subdural hematoma (SDH) accounts for over 50% TBI, the occurrence dysphagia in this subtype has not been investigated yet. All patients SDH admitted author's institution between years 2007 2020 were included study. Patients clinical suspicion received swallowing assessment by speech language pathologist (SLP)....
Abstract Background: Dysphagia is a frequent finding on intensive care units (ICUs) and associated with increased reintubation rates, pneumonia, prolonged ICU-stay. Only limited numbers of ICUs have access to Speech Language Pathologist (SLP). Hence, it falls upon the critical team estimate dysphagia risk define safest feeding route. Therefore, aim this study was evaluate if route established by ICU-team changed after standardized assessment (DA) an SLP. Furthermore, we tried identify...