- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Hormonal and reproductive studies
- Ovarian function and disorders
- Pluripotent Stem Cells Research
- Erythrocyte Function and Pathophysiology
- Xenotransplantation and immune response
- Heat shock proteins research
- Genital Health and Disease
- Bat Biology and Ecology Studies
- Tissue Engineering and Regenerative Medicine
- CRISPR and Genetic Engineering
Universidad Autónoma Metropolitana
2020-2025
Universidad de Murcia
2021-2023
Instituto Murciano de Investigación Biosanitaria
2022
Infertility is increasingly recognized as being closely linked to obesity in humans. The successful production of fertile spermatozoa requires adequate spermatogenesis within the testis and proper maturation through epididymis. This study aimed evaluate impact body adiposity on male fertility, focusing sperm parameters, epididymal maturation, capacitation Wistar rats. Male rats were randomized into three dietary groups over four weeks: a control group receiving less than 4% lard, regular...
Abstract Boar ejaculate is composed of sperm cells and seminal plasma (SP) emitted in different fractions (pre-sperm fraction; spermatic-rich intermediate post-spermatic fraction), with composition SP volume, which could influence the quality during doses preparation, conservation, interaction female reproductive tract. In artificial insemination (AI) centers, are usually prepared fractions, but inclusion other although controversial, beginning to be applied. The objective was evaluate...
Abstract Recent evidence supports involvement of the acute phase protein haptoglobin in numerous events during mammalian reproduction. The present study represents an in-depth investigation expression and secretion porcine oviduct uterus, assesses its effect on vitro embryo production. A systematic was made sows different oestrous stages: late follicular, early luteal stages. Relative mRNA abundance quantified by RT-qPCR. In addition, analysed immunohistochemistry results were complemented...
Abstract The Corynorhinus mexicanus bat is characterized by a specific form of reproductive asynchrony between males and females. After mating, some sperm remain in the male's epididymis, organ where had matured. It has not yet been determined if apoptotic markers participate process maturation and/or elimination these cells, so studying this topic essential for our understanding species. Male bats were collected during three stages: Before mating; Mating phase; mating final phase, which we...
Each year, tens of thousands people worldwide die end-stage organ failure due to the limited availability organs for use in transplantation. To meet this clinical demand, one last frontiers regenerative medicine is generation humanized pigs from pluripotent stem cells (PSCs) via blastocyst complementation. For this, organ-disabled pig models are needed. As endothelial (ECs) play a critical role xenotransplantation rejection every organ, we aimed produce hematoendothelial-disabled embryos...