- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Brain Metastases and Treatment
- Cancer Immunotherapy and Biomarkers
- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Lung Cancer Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Glioma Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Treatment and Pharmacology
- Colorectal Cancer Treatments and Studies
- Medical Imaging Techniques and Applications
- Breast Cancer Treatment Studies
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Chemotherapy-related skin toxicity
- Neutropenia and Cancer Infections
- Myasthenia Gravis and Thymoma
- Radiopharmaceutical Chemistry and Applications
- Pituitary Gland Disorders and Treatments
- Multiple and Secondary Primary Cancers
- Infection Control and Ventilation
- Cancer Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
Azienda Usl Toscana Centro
2021-2024
Technoport (Luxembourg)
2023
Azienda Ospedaliero-Universitaria Careggi
2017-2022
University of Florence
2017-2022
Ospedale Santa Maria Annunziata
2022
Université de Lorraine
2020
Centre National de la Recherche Scientifique
2020
Institut de Cancérologie de Lorraine
2020
München Klinik
2019
University of Verona
2017
Thymoma is a rare mediastinal neoplasia. Surgery the backbone of treatment, but role postoperative radiotherapy (PORT) remains controversial. We aimed to obtain data on survival and safety in patients treated with PORT three different Italian institutions.We retrospectively analyzed 183 consecutive who underwent surgery from 1981 2015. According Masaoka-Koga staging system, 39.3%, 32.7%, 18.6% 9.8% were stage I, II, III IV disease, respectively. was indicated 114 (62.3%), while 69 subjects...
Purpose To determine dose constraints that correlate with alopecia in patients treated photon-based Volumetric Modulated Arc Therapy (VMAT) for primary brain tumors. Methods During the treatment planning process, scalp was drawn as a region of interest. Dose received by 0.1 cc (D0.1cc), mean (Dmeanscalp), volumes receiving different doses (V16Gy, V20Gy, V25Gy, V30Gy, V35Gy, V40Gy, and V43Gy) were registered scalp. Alopecia assessed according to Common Terminology Criteria Adverse Events...
Limited evidence is available concerning the selection criteria and outcomes of platinum unfit newly diagnosed advanced NSCLC patients receiving single-agent chemotherapy. We retrospectively collected data on consecutive, stage IIIB-IV, EGFR/ALK negative PD-L1 < 50% treated with first-line single agent Baseline characteristics, outcome measures toxicities were recorded, as well according to which treatment was made what percentage did not receive a platinum-based Two-hundred twenty-one...
Although the published data about safety of vaccines in patients with cancer are scarce,1Waissengrin B Agbarya A Safadi E Padova H Wolf I Short-term BNT162b2 mRNA COVID-19 vaccine treated immune checkpoint inhibitors.Lancet Oncol. 2021; 22: 581-583Summary Full Text PDF PubMed Scopus (150) Google Scholar National Comprehensive Cancer Network recommends that should be prioritised for vaccination2Recommendations NCCN Vaccination Advisory Committee, version...
Abstract Background Oral mucositis is a side effect of treatment regimens containing 5‐fluorouracil (5‐FU). The purpose this study was to present our evaluation see if rosiglitazone (RGZ) protected normal tissues from chemotherapy‐induced oral mucositis. Methods C57BL/6J mice were treated with 5‐FU for 5 days, or without RGZ. Mice euthanized after 5, 8, 11, 15 and mucosal segments collected. Results RGZ did not affect the 5‐FU‐induced decrease in mouse body weight. caused loss epithelial...
Introduction: This retrospective study analyzes the safety and feasibility of concurrent chemoradiotherapy (CRT) in adjuvant treatment soft tissue sarcoma (STS). Methods: A total 158 patients with STS were retrospectively analyzed. Anthracycline-based computed tomography was performed high-risk patients. Acute radiotherapy toxicity chemotherapy-related assessed according to Common Terminology Criteria for Adverse Events 4.0; late recorded Radiation Therapy Oncology Group/European...
Afatinib, a second-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, is effective as first-line treatment in patients with EGFR-mutated non-small cell lung cancer (NSCLC). We report 2 cases of locally advanced NSCLC treated neoadjuvant setting EGFR inhibitor at University Florence/Careggi Hospital. In both cases, afatinib was used for up to 3 months, until 1 week before surgery. Both achieved significant reduction (downstaging) the pulmonary mass and...
Concurrent chemotherapy and radiotherapy (cCRT) is considered the standard treatment of locally advanced non-small cell lung cancer (LA-NSCLC). Unfortunately, management still heterogeneous across different specialists. A multidisciplinary approach needed in this setting due to recent, promising results obtained by consolidative immunotherapy. The aim survey assess current LA-NSCLC Italy. From January April 2018, a 15-question focusing on diagnostic/therapeutic was sent 1,478 e-mail...
In this study, we focused mainly on the metastatic process related to surgery in squamous cell carcinoma of upper aerodigestive tract.We attempted detect isolated cells (CTCs) head and neck (SCCHN) blood stream before, during after surgery.With aim, realized a prospective study analyzing impact CTC level period 9 days.Two widely used techniques were : PCR real time Cell Search.