A5018899823- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Colorectal Cancer Treatments and Studies
- Cancer Immunotherapy and Biomarkers
- Landslides and related hazards
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Cancer therapeutics and mechanisms
- Cancer Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- RNA modifications and cancer
- Cancer, Hypoxia, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- HER2/EGFR in Cancer Research
- Gastric Cancer Management and Outcomes
- Rock Mechanics and Modeling
- Brain Metastases and Treatment
- Nutrition and Health in Aging
- Cancer Treatment and Pharmacology
- Neuroblastoma Research and Treatments
- Genetic factors in colorectal cancer
- Occupational and environmental lung diseases
- Tuberculosis Research and Epidemiology
Roche (Switzerland)
2022-2024
Ospedale di Spoleto
2022-2024
University of Naples Federico II
2022-2023
University of Verona
2012-2021
New York University Abu Dhabi
2021
Azienda Ospedaliera Universitaria Integrata Verona
2004-2020
Associazione Italiana Di Oncologia Medica
2020
Presidio Ospedaliero
2020
University of Milan
1991-2016
University Hospital Foundation
2016
Unresponsiveness to erythropoiesis-stimulating agents, occurring in 30% 50% of patients, is a major limitation the treatment chemotherapy-related anemia. We have prospectively evaluated whether intravenous iron can increase proportion patients with anemia who respond darbepoetin.Between December 2004 and February 2006, 149 lung, gynecologic, breast, colorectal cancers >or= 12 weeks planned chemotherapy were enrolled from 33 institutions. Patients required hemoglobin <or= 11 g/L no absolute...
// Emilio Bria 1,* , Sara Pilotto Eliana Amato 2 Matteo Fassan Silvia Novello 3 Umberto Peretti 1 Tiziana Vavalà Stefania Kinspergher Luisella Righi Antonio Santo Brunelli 4 Vincenzo Corbo Giglioli Isabella Sperduti 5 Michele Milella 6 Marco Chilosi Aldo Scarpa 2,4 and Giampaolo Tortora Department of Medicine, Medical Oncology, University Verona, Azienda Ospedaliera Universitaria Integrata, Italy ARC-NET Center for Applied Research on Cancer, Torino, A.O.U. San Luigi, Orbassano, Pathology...
Abstract Purpose: LKB1 is a key sensor of metabolic stress, including hypoxia and glucose deprivation, two features the tumor microenvironment exacerbated by antiangiogenic therapy. We investigated role as potential predictive marker sensitivity to bevacizumab in advanced non–small cell lung cancer (aNSCLC). Experimental design: retrospectively analyzed expression IHC 98 samples from 125 patients with aNSCLC, 59 treated chemotherapy 39 plus bevacizumab. intensity was recoded classes...
Purpose To compare efficacy of pemetrexed versus plus carboplatin in pretreated patients with advanced non–small-cell lung cancer (NSCLC). Patients and Methods NSCLC, progression during or after first-line platinum-based chemotherapy, were randomly assigned to receive (arm A) B). Primary end point was progression-free survival (PFS). A preplanned pooled analysis the results this study those NVALT7 carried out assess impact added terms overall (OS). Results From July 2007 October 2009, 239 A,...
Pulmonary adenocarcinoma with enteric differentiation (PAED) is a rare subtype of lung recently recognized in the WHO classification. It defined as an which component exceeds 50% and have to show expression at least 1 immunohistochemical marker differentiation. Although definition this tumor type very important, above all differential diagnosis between primary metastasis colorectal adenocarcinoma, cancer still lacks distinctive molecular signature. We recruited largest series literature...
PURPOSE Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, yet their use is associated with immune-related adverse events (irAEs). Estimating the prevalence and patient impact of these irAEs in real-world data setting critical for characterizing benefit/risk profile ICI therapies beyond clinical trial population. Diagnosis codes, such as International Classification Diseases do not comprehensively illustrate a patient's care journey offer no insight into drug-irAE...
Although first-line therapy for patients affected by advanced mesothelioma is well established, there a lack of data regarding the impact second-line treatment. We retrospectively collected mesothelioma, already treated with based on pemetrexed and platin, response (partial or stable disease) lasting at least 6 months, re-treated pemetrexed-based progression. The primary objective was to describe time progression overall survival after re-treatment. Overall across several Italian oncological...
O artigo analisa a gestão financeira de uma microempresa, utilizando como fio condutor o controle do fluxo caixa em oficina mecânica automotiva. estudo visa demonstrar aplicação estratégias financeiras simples pode contribuir para organização, estabilidade e sustentabilidade negócio, enfatizando importância das entradas saídas, da separação entre finanças pessoais empresariais criação reserva financeira. A metodologia empregada consiste pesquisa aplicada, descritiva exploratória, com...
Squamous lung carcinoma lacks specific "ad hoc" therapies. Amplification of chromosome 3q is the most common genomic aberration and this region harbours genes having role as novel targets for therapeutics. There no standard definition on how to score report amplification. False versus true chromosomal amplification in squamous cell may have tremendous impact trials involving drugs which target DNA zones mapping 3q. Forty carcinomas were analyzed by FISH assess aCGH was performed...
BackgroundNutritional derangements are common hallmarks of non-small-cell lung cancer (NSCLC). Nevertheless, their early detection is overlooked in clinical routine. This study aimed to evaluate nutritional status and its correlation with outcome NSCLC patients.MethodsData regarding patients undergoing evaluation were prospectively collected (May 2016–October 2018). Nutritional risk was assessed by Risk Screening 2002 (NRS-2002). Bilateral psoas major muscles measured at L3 vertebrae level...
// Elisa Roca 1 , Giuseppe Colloca 2 Fiorella Lombardo Andrea Bellieni Alessandra Cucinella Giorgio Madonia Licia Martinelli Maria Damiani Ilaria Zampieri and Antonio Santo Oncologia Toracica - Lung Unit, Ospedale P. Pederzoli Via Monte Baldo, Peschiera del Garda (VR), Italy Dipartimento di Scienze dell'invecchiamento, Neurologiche, Ortopediche e della testa-collo, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Correspondence to: Roca, email: elisaroca@gmail.com ORCID:...
BACKGROUND Studies of chemotherapy for patients with small cell lung carcinoma (SCLC) have shown that teniposide (T) may higher activity than etoposide (E). In this randomized, controlled Phase III study, the authors compared cyclophosphamide, doxorubicin, and vincristine (CAV) E CAV T as induction treatments SCLC. A second objective study was to who had achieved complete response (CR). They were considered a randomization maintenance therapy, in which they would receive either recombinant...
Limited evidence is available concerning the selection criteria and outcomes of platinum unfit newly diagnosed advanced NSCLC patients receiving single-agent chemotherapy. We retrospectively collected data on consecutive, stage IIIB-IV, EGFR/ALK negative PD-L1 < 50% treated with first-line single agent Baseline characteristics, outcome measures toxicities were recorded, as well according to which treatment was made what percentage did not receive a platinum-based Two-hundred twenty-one...