A5029853637- Carbohydrate Chemistry and Synthesis
- Surfactants and Colloidal Systems
- Lipid Membrane Structure and Behavior
- Glycosylation and Glycoproteins Research
- Enzyme Catalysis and Immobilization
- biodegradable polymer synthesis and properties
- Analytical Chemistry and Chromatography
- Click Chemistry and Applications
- Chemical Synthesis and Analysis
- Advanced biosensing and bioanalysis techniques
- Tribology and Wear Analysis
- Liquid Crystal Research Advancements
- Lubricants and Their Additives
- Nanoparticle-Based Drug Delivery
- Food Chemistry and Fat Analysis
- Microbial Metabolic Engineering and Bioproduction
- Electrospun Nanofibers in Biomedical Applications
- Microplastics and Plastic Pollution
- Synthesis of Organic Compounds
- Synthetic Organic Chemistry Methods
- Advanced Polymer Synthesis and Characterization
- Advanced Drug Delivery Systems
- X-ray Diffraction in Crystallography
- Bioactive Compounds and Antitumor Agents
- Free Radicals and Antioxidants
University of Malaya
2015-2025
Hospital Kuala Lumpur
2018-2020
Binghamton University
2004
Institut de Chimie Organique et Analytique
2004
Université d'Orléans
2004
Martin Luther University Halle-Wittenberg
1997
Universität Hamburg
1996-1997
The biosynthesis and characterization of medium chain length poly-3-hydroxyalkanoates (mcl-PHA) produced by Pseudomonas putida Bet001 isolated from palm oil mill effluent was studied. mcl-PHA in this newly microorganism follows a growth-associated trend. Mcl-PHA accumulation ranging 49.7 to 68.9% on cell dry weight (CDW) basis were observed when fatty acids octanoic acid (C8∶0) oleic (C18∶1) used as sole carbon energy source. Molecular the polymer found be 55.7 77.7 kDa. Depending type used,...
Growth associated biosynthesis of medium chain length poly-3-hydroxyalkanoates (mcl-PHA) in Pseudomonas putida Bet001 isolated from palm oil mill effluent was studied. Models with substrate inhibition terms described well the kinetics its growth. Selected fatty acids (C8:0 to C18:1) and ammonium were used as carbon nitrogen sources during growth PHA biosynthesis, resulting accumulation about 50 69% (w/w) yields ranging 10.12 g L(-1) 15.45 L(-1), respectively. The monomer composition ranges...
Abstract An economically viable route towards doubled headed alkyl triazole glycoside surfactants (ATG) is reported. The approach applies common industrial precursors leading to reasonable product yields. interface-dominating hydrophilic domain favors curved assemblies over lamellar analogs, thereby enhancing the water solubility of surfactants. In terms assembly behavior, double ATG matched corresponding chain analogs polyglucosides (APG), implying a compensation triazols’ hydrophobic...
The effect of chain branching on glycolipid thermotropic and lyotropic phases was investigated for a series synthetic β-D-glucosides derived from Guerbet alcohols, whose total hydrocarbon length ranged C8 to C24. compounds, which can be viewed as isosteric mimics glycoglycerolipids, were synthesised in high purity their liquid crystalline studied using optical polarising microscopy (OPM), small-angle X-ray diffraction. When dry, the shortest compound (total C8) exhibits monotropic Lα phase...
In an attempt to relate the geometry of glycolipid assemblies with molecular packing constraints, surface areas per molecule for straight and branched-chain alkyl glycosides varying chain length are calculated. Effects temperature, water content, sugar size paraffin analysed based on closest assumption. The results show a continuous increase interface between hydrophilic hydrophobic domain growing dominance in bulkiness either domain, until it reaches maximum hexagonal phases. area molecule,...
Water-driven self-assembly of lipids displays a variety liquid crystalline phases that are crucial for membrane functions. Herein, we characterize the temperature-induced phase transitions in two compositions an aqueous system octyl β-D-glucoside (βGlcOC(8)) system, using steady-state and time-resolved fluorescence measurements. The hexagonal ↔ micellar cubic lamellar were investigated tryptophan (Trp) its ester derivatives (Trp-C(4) Trp-C(8)) to probe polar headgroup region pyrene...
New design of cationic magnetic core–shell nanoparticles fabricated with a large hydrophilic group (carbohydrate molecules) enabled high adsorption nucleic acid, easy isolation and controlled the movement by applying an external field.
Glycolipids form materials of considerable potential for a wide range surfactant and thin film applications. Understanding the effect glycolipid covalent structure on properties their thermotropic lyotropic assemblies is key step toward rational design new glycolipid-based materials. Here, we perform molecular dynamics simulations anhydrous bilayers dodecyl β-maltoside, β-cellobioside, β-isomaltoside, C12C10 branched β-maltoside. Specifically, examine consequences chain branching headgroup...
Simulations on bilayers have previously proven their ability to provide insights membrane function, e.g. cell fusion. Most simulations are based the major components of membranes, which phospholipids and cholesterol. Membranes can be explained hydrophilic hydrophobic interactions permeated through hydrogen bonding, van der Waals repulsion forces. Whereas especially gained significant attention in bio‐related modelling simulations, glycolipids, constitute another component not been likewise...
Lyotropic liquid crystal phases are related to biological entities such as cell membranes, well technological applications, for example, emulsifier and drug-delivery systems. We characterized here one of the most stable lyotropic βMaltoOC12 lipid, hexagonal phase (comprised 65% (w/w) aqueous formulation n-dodecyl β-d-maltoside), using fluorescent probes. Probing different parts polar head group region tryptophan (Trp) two its ester derivatives (Trp-C4 Trp-C8) indicates a polarity gradient....
Abstract Ecological concerns over the accumulation of polymeric waste material and demand for functionalized polymers in specialty applications have promoted extensive research on different controlled degradation processes their use. The production or modified by conventional synthetic routes is expensive time consuming. However, advances technology become an enabling factor functionalization. Mild irradiation, ozonization, enzymatic are among that been explored polymer modification....