Iris Koch

ORCID: 0000-0003-4441-606X
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About
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Research Areas
  • Arsenic contamination and mitigation
  • Heavy metals in environment
  • Heavy Metal Exposure and Toxicity
  • Mercury impact and mitigation studies
  • Environmental Toxicology and Ecotoxicology
  • Analytical chemistry methods development
  • Lichen and fungal ecology
  • Mine drainage and remediation techniques
  • Per- and polyfluoroalkyl substances research
  • Chromium effects and bioremediation
  • Toxic Organic Pollutants Impact
  • Nanoparticles: synthesis and applications
  • Electrochemical Analysis and Applications
  • Micro and Nano Robotics
  • Radioactive element chemistry and processing
  • Atmospheric chemistry and aerosols
  • Radioactivity and Radon Measurements
  • Magnetic properties of thin films
  • Coal and Its By-products
  • Fluoride Effects and Removal
  • Topological Materials and Phenomena
  • Microbial bioremediation and biosurfactants
  • Microfluidic and Bio-sensing Technologies
  • Characterization and Applications of Magnetic Nanoparticles
  • Quantum many-body systems

Royal Military College of Canada
2015-2025

Max Planck Institute for Biology
2022

University of Kassel
2013-2021

Queen's University
2004-2021

Max Planck Institute for Developmental Biology
2019

Geological Survey of Canada
2010

Natural Resources Canada
2010

British Geological Survey
2006-2010

Simon Fraser University
2004-2009

DHI
2006

Bioaccessibility tests and mineralogical analyses were performed on arsenic-contaminated tailings soils from gold mine districts of Nova Scotia, Canada, to examine the links between soil composition, mineralogy, arsenic bioaccessibility. Arsenic bioaccessibility ranges 0.1% 49%. A weak correlation was observed total bioaccessible concentrations, not correlated with other elements. Bulk X-ray absorption near-edge structure analysis shows in these near-surface samples is mainly pentavalent...

10.1021/es9035682 article EN Environmental Science & Technology 2010-03-10

Elevated levels of arsenic in Yellowknife, NWT, Canada, from historic and recent gold mine operations, are increasing concern to Yellowknife residents. The study plants is a part ongoing bioavailability food chain research. A variety were analyzed for total water soluble species. included vascular bryophytes (mosses). Total amounts greatest mosses varied greatly within specimens the same plant species different locations. Mostly inorganic extracted using methanol/water (1:1). This result...

10.1021/es9906756 article EN Environmental Science & Technology 1999-11-18

Arsenic is an element that ubiquitous in the environment and known to form compounds with toxic, even carcinogenic properties. toxicity a function of its chemical (species). Identification arsenic species necessary accurately determine transformation fate arsenicals as well actual risk posed by contamination. We report X-ray absorption near-edge structure (XANES) measurements 16 biologically important compounds. Solid aqueous standards were studied for differences XANES spectral features,...

10.1021/es049358b article EN Environmental Science & Technology 2004-11-18

Arsenic is naturally present in marine ecosystems, and these can become contaminated from mining activities, which may be of toxicological concern to organisms that bioaccumulate the metalloid into their tissues. The toxic properties arsenic are dependent on chemical form it found (e.g., inorganic arsenicals vs nontoxic arsenobetaine), two analytical techniques, high performance liquid chromatography coupled with inductively plasma mass spectrometry (HPLC-ICP-MS) X-ray absorption...

10.1021/es203812u article EN Environmental Science & Technology 2012-02-14

The two complementary techniques high performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC-ICP-MS) and X-ray absorption near edge structure (XANES) analysis were used to assess arsenic speciation in freshwater phytoplankton zooplankton collected from arsenic-contaminated lakes Yellowknife (Northwest Territories, Canada). Arsenic concentrations lake water ranged 7 μg L(-1) a noncontaminated 250 mine-contaminated lakes, which resulted ranging 340 mg kg(-1) d.w....

10.1021/es2025092 article EN Environmental Science & Technology 2011-10-23

Abstract Bioaccessibility is a measurement of substance's solubility in the human gastro-intestinal system, and often used risk assessment soils. The present study was designed to determine variability among laboratories using different methods measure bioaccessibility 24 inorganic contaminants one standardized soil sample, standard reference material NIST 2710. Fourteen total 17 extraction methods. between assessed by calculating reproducibility relative deviations (RSDs), where sum...

10.1080/10934529.2013.731817 article EN Journal of Environmental Science and Health Part A 2013-05-01

The fruiting bodies, or mushrooms, of terrestrial fungi have been found to contain a high proportion the nontoxic arsenic compound arsenobetaine (AB), but data gaps include limited phylogenetic diversity for which speciation is available, focus on mushrooms with higher total concentrations, and unknown formation role AB in mushrooms. To address these, 46 different fungus species (73 samples) over diverse range groups were collected from Canadian grocery stores background arsenic-contaminated...

10.1021/es5038468 article EN Environmental Science & Technology 2014-11-22

The distribution and chemical form (speciation) of arsenic in terrestrial food chains determines both the amount available to higher organisms, toxicity this metalloid affected ecosystems. Invertebrates are part complex webs. This paper provides concentrations speciation profiles for eight orders invertebrates collected at three historical gold mine sites one background site Nova Scotia, Canada. Total concentrations, determined by inductively coupled plasma mass spectrometry (ICP-MS), were...

10.1021/es900086r article EN Environmental Science & Technology 2009-05-15

A Autosomal-dominant ELANE mutations are the most common cause of severe congenital neutropenia. Although majority neutropenia patients respond to daily granulocyte colony stimulating factor, approximately 15 % do not this cytokine at doses up 50 μg/kg/day and will develop myelodysplasia or acute myeloid leukemia. “Maturation arrest,” failure marrow progenitors form mature neutrophils, is a consistent feature associated As mutant neutrophil elastase abnormality, we hypothesized that could be...

10.3324/haematol.2019.221804 article EN cc-by-nc Haematologica 2019-06-27
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