- COVID-19 diagnosis using AI
- Radiomics and Machine Learning in Medical Imaging
- AI in cancer detection
- Advanced Image and Video Retrieval Techniques
- Estrogen and related hormone effects
- Image Retrieval and Classification Techniques
- Neurogenesis and neuroplasticity mechanisms
- QR Code Applications and Technologies
- Artificial Intelligence in Healthcare and Education
- Alzheimer's disease research and treatments
- Hypothalamic control of reproductive hormones
- COVID-19 and healthcare impacts
- Neuroinflammation and Neurodegeneration Mechanisms
- Internet Traffic Analysis and Secure E-voting
- Chronic Kidney Disease and Diabetes
- Efficiency Analysis Using DEA
- Melanoma and MAPK Pathways
- Renal and Vascular Pathologies
- Artificial Intelligence in Healthcare
- Artificial Immune Systems Applications
- Advanced Steganography and Watermarking Techniques
- Menstrual Health and Disorders
- Statistical Methods in Clinical Trials
- Research in Cotton Cultivation
- Musculoskeletal Disorders and Rehabilitation
WinnMed
2021-2025
Mayo Clinic in Florida
2021-2025
Research Center for Information Technology Innovation, Academia Sinica
2025
Phillips Exeter Academy
2024
National Taipei University of Technology
2023
Anhui Academy of Agricultural Sciences
2023
Cotton Research Institute
2023
State Key Laboratory of Cotton Biology
2023
Nantong University
2023
Mayo Clinic in Arizona
2020-2022
This study addressed the challenge of training generative adversarial networks (GANs) on small tabular clinical trial datasets for data augmentation, which are known to pose difficulties in due limited sample sizes. To overcome this obstacle, a hybrid approach is proposed, combining synthetic minority oversampling technique (SMOTE) initially augment original more substantial size improving subsequent GAN with Wasserstein conditional network gradient penalty (WCGAN-GP), proven its...
Cardiac cachexia (CC) is a severe complication of advanced heart failure (HF), characterized by involuntary weight loss and muscle wasting, leading to poor outcomes higher mortality. Despite its severity, CC remains under-recognized undertreated, lacking targeted therapies specifically addressing pathophysiology. Glucagon-like peptide-1 receptor agonists (GLP-1RAs), though beneficial in reducing cardiovascular risk patients with HF, may exacerbate wasting cachectic patients, necessitating...
Both the clonal selection algorithm (CSA) and ant colony optimization (ACO) are inspired by natural phenomena effective tools for solving complex problems. CSA can exploit explore solution space parallely effectively. However, it not use enough environment feedback information thus has to do a large redundancy repeat during search. On other hand, ACO is based on concept of indirect cooperative foraging process via secreting pheromones. Its positive ability nice but its convergence speed slow...
Abstract Pathogenic tau accumulation fuels neurodegeneration in Alzheimer’s disease (AD). Enhancing aging brain’s resilience to pathology would lead novel therapeutic strategies. DAP12 (DNAX-activation protein 12) is critically involved microglial immune responses. Previous studies have showed that mice lacking tauopathy exhibit higher but are protected from tau-induced cognitive deficits. However, the exact mechanism remains elusive. Our current study uncovers a via interaction with...
Pathogenic tau accumulation fuels neurodegeneration in Alzheimer's disease (AD). Enhancing aging brain's resilience to pathology would lead novel therapeutic strategies. DAP12 (DNAX-activation protein 12) is critically involved microglial immune responses. Previous studies have showed that mice lacking tauopathy exhibit higher but are protected from tau-induced cognitive deficits. However, the exact mechanism remains elusive. Our current study uncovers a via interaction with...
Arsenic trioxide (As 2 O 3 ), has been used for centuries in traditional Chinese medicine; it considerable efficacy the treatment of relapsed acute promyelocytic leukemia, inducing partial differentiation and promoting apoptosis malignant promyelocytes. Although a number studies have demonstrated that As potent activity against cell growth series leukemia lines, little information is available regarding this compound's effect on solid tumor lines. In study, we investigated effects vitro...
The current state of cancer therapeutics has been moving away from one-size-fits-all cytotoxic chemotherapy, and towards a more individualized specific approach involving the targeting each tumor's genetic vulnerabilities. Different tumors, even same type, may be reliant on certain cellular pathways than others. With modern advancements in our understanding genome sequencing, these can discovered. Investigating millions possible small molecule inhibitors for kinase vitro, however, would...
QR codes, prevalent in daily applications, lack visual appeal due to their conventional black-and-white design. Integrating aesthetics while maintaining scannability poses a challenge. In this paper, we introduce novel diffusion-model-based aesthetic code generation pipeline, utilizing pre-trained ControlNet and guided iterative refinement via classifier guidance (SRG) based on the proposed Scanning-Robust Loss (SRL) tailored with mechanisms, which ensures both scannability. To further...
A personalized medical recommendation system is an intelligent that utilizes data to provide targeted advice and services individuals. With the lack of accumulation development data, systems have great potential in improving effectiveness saving resources. This article aims explore principles, methods, applications based on data.
With the success of Diffusion Models for image generation, technologies also have revolutionized aesthetic Quick Response (QR) code generation. Despite significant improvements in visual attractiveness beautified codes, their scannabilities are usually sacrificed and thus hinder practical uses real-world scenarios. To address this issue, we propose a novel Diffusion-based QR Code generator (DiffQRCoder) to effectively craft both scannable visually pleasing codes. The proposed approach...
Abstract Background: Leuprorelin is an analog of gonadotropin-releasing hormone that used for the therapy central precocious puberty (CPP). The aims this prospective, open label, multicenter clinical trial were to establish its efficacy and safety during long-term use. Methods: Patients, who all children, treated with 1.88 3.75 mg leuprorelin subcutaneously once every 4 weeks a total 96 between 2015 2018. primary endpoint was rate occurrence adverse events (AEs) secondary no progression in...
The optimum fertilizer application rate and economic benefit of early maturing cotton in the Yangtze River Basin were studied.The varieties (Wankemian-1 Wanmian-191) rates (F1, F2, F3) set main producing area Anhui Province by field split plot experiment.The effects different on growth, yield, quality analyzed.The results showed that growth period, first fruit segment, branch number plant height two increased significantly with increase amount.When yield seed lint reached F2 level,...