A5079288499- Cardiovascular Health and Disease Prevention
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Antioxidant Activity and Oxidative Stress
- Sexual function and dysfunction studies
- Blood Pressure and Hypertension Studies
- Hormonal and reproductive studies
- Diagnosis and Treatment of Venous Diseases
- Multiple Sclerosis Research Studies
- Diabetic Foot Ulcer Assessment and Management
- Cerebral Venous Sinus Thrombosis
- Acute Ischemic Stroke Management
- Lysosomal Storage Disorders Research
- Abdominal vascular conditions and treatments
- COVID-19 Clinical Research Studies
- Proteoglycans and glycosaminoglycans research
- Systemic Sclerosis and Related Diseases
- Bone health and osteoporosis research
- Glycogen Storage Diseases and Myoclonus
- Antiplatelet Therapy and Cardiovascular Diseases
- Atherosclerosis and Cardiovascular Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pathogenesis and Treatment of Hiccups
University of Catania
2006-2024
Marconi University
2024
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2020
Ferrarotto Hospital
2013-2015
Ospedale Garibaldi
2003
We screened a cohort of subjects affected by various degree dyspepsia to reveal if they presented reduction the aorto-mesenteric angle and diagnose suspected cases superior mesenteric artery (SMA) syndrome.Controlled, prospective, study.Subjects were studied as outpatients.The study investigated total 3622 referred our department their general practitioners for and/or abdominal pain. Interventions. Abdominal ultrasonography with power colour Doppler, gastroduodenoscopy, hypotonic...
Deregulation of matrix metalloproteinases (MMPs) is an important factor contributing to the development vascular lesions. Plasma levels and zymographic activities MMP-2 MMP-9 were investigated in type II diabetics with (n = 51) or without 42) peripheral artery disease (PAD) normal volunteers 23). higher (p < 0.01) > 0.05) PAD comparison volunteers. Similarly, 0.0001) had plasma than both positively correlated their levels. activity was 0.05). comparision Together, these results indicate that...
Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis that associated with systemic inflammation. The aim our study was to assess whether plasma markers inflammation increased after exercise in patients PAD. conducted on two groups 20 subjects each: one group (mean age 68.4 +/- 5.09 years) affected by PAD claudication, while the other consisted healthy controls (66.9 6.1 years). Concentrations interleukin 6 (IL-6) and tumor necrosis factor alpha (TNFalpha) were...
Recent studies have reported early atherosclerosis in patients with inflammatory bowel disease (IBD). In these patients, the chronic low-grade inflammation may predispose to vascular remodelling and arterial stiffening. We aimed at studying stiffness IBD patients.Thirty-two without cardiovascular risk factors 32 matched controls were enrolled (age 19-49 years). SphygmoCor device (AtCor Medical, Sydney, Australia) was used measure carotid-femoral carotid-radial (muscular artery) pulse wave...
Purpose: To evaluate if jugular vein flow restoration in various venographic defects indicative of chronic cerebrospinal venous insufficiency (CCSVI) multiple sclerosis (MS) patients can have positive effects on cerebral lesions identified using magnetic resonance imaging (MRI). Materials and Methods: The Brave Dreams trial ( ClinicalTrials.gov identifier NCT01371760) was a multicenter, randomized, parallel group, double-blind, sham-controlled to assess the efficacy venoplasty MS with CCSVI....
Chronic cerebrospinal venous insufficiency (CCSVI) has been associated to multiple sclerosis (MS).To evaluate the possible association between CCSVI and MS, using a population-based control design.A random cohort of 148 incident MS patients were enrolled in study. We have also studied 20 with clinically isolated syndrome (CIS), 40 other neurological diseases (OND), 172 healthy controls. Transcranial (TCC) Echo Color Doppler (ECD) carried out 380 subjects. A subject was considered positive if...
ABSTRACT: We recently showed the diagnostic value of a new immunophenotype blood endothelial progenitor cells (EPC) (CD45 − /CD34 + /CD144 ) and microparticles (EMP) /annexin V in patients with arterial erectile dysfunction (AED), particularly associated late‐onset hypogonadism and/or metabolic syndrome. In addition, we evaluated effects androgen replacement therapy, aerobic physical activity, tadalafil administration on these markers. The aim this study was to evaluate serum concentrations...
Numerous reports have shown the relationship between carotid artery atherosclerosis and coronary disease (CAD). However, association complex CAD evaluated by SYNTAX score (SxScore) prevalence of lesion (CL) has not been fully investigated. We sought to assess in patients with multivessel assessed SxScore severity features atherosclerosis.Subjects were 204 consecutive angiography no previous history that underwent ultrasound scan from June 2012 2013. Presence CL, significant (SCD) plaque...
Abstract Extracranial internal carotid artery (EICA) kinking and coiling are the most frequently reported anomalies in literature. Embryogenic acquired causes for such have been postulated but prevalence of has not well characterized across age categories. The aim this study is to evaluate EICA among different groups better understand its potential changes during course life. A total 2856 subjects aged 0 96 years were studied by echo-color Doppler (ECD). Morphology anatomical assessed....
<i>Background/Aims:</i> Recent data have addressed the issue of higher levels homocysteine (Hcy) and endothelin-1 (ET-1) in end-stage renal disease (ESRD) that may be considered an independent predictor for cardiovascular disease. The prevalence peripheral arterial (PAD) patients with ESRD has been reported to relevant, highlighting its clinical importance. We aimed explore therapeutic role propionyl-<i>L</i>-carnitine (PLC) hemodialysis PAD by measuring...
(1) Background: As a lysosomal storage disorder, Fabry’s disease (FD) shows variable clinical manifestations. We applied our multidisciplinary approach to identify any organ damage in sample of adult patients with different pathogenic variants. (2) Methods: 49 participants (mean age 44.3 ± 14.2 years; 37 females), underwent multidimensional and instrumental assessment. (3) Results: At diagnosis, mean enzymatic activity was 5.2 4.6 nM/mL/h females 1.4 0.5 males (normal values > 3.0), whereas...
Abstract: The aim of this study was to evaluate whether the blood concentrations a new immunophenotype circulating late endothelial progenitor cells (EPC) and microparticles (EMP) varies in patients with arterial erectile dysfunction (aED) abnormalities other districts. To accomplish this, cavernous artery peak systolic velocity (PSV), acceleration time (AT), intima‐media thickness (IMT) were determined after intracavernous administration alprostadil by echo‐color Doppler 80 consecutive (age...
Fifty-six patients with superficial thrombovaricophlebitis of the lower limbs were enrolled in an open and multicenter (4 centers) trial for a period thirty days. Patients randomly allocated to three treatment groups receive new low-molecular-weight dermatan sulfate (Desmin) at dose, respectively, 100 mg once daily by subcuta neous (SC) route, twice day SC, 200 intramuscular (IM) route. The general local tolerability clinical efficacy drug evaluated means clinical, instrumental, laboratory...