- Diet and metabolism studies
- Gastrointestinal motility and disorders
- Neuropeptides and Animal Physiology
- Urinary Bladder and Prostate Research
- Congenital gastrointestinal and neural anomalies
- Caveolin-1 and cellular processes
- Neuroscience of respiration and sleep
- Tissue Engineering and Regenerative Medicine
- Muscle Physiology and Disorders
- Cardiomyopathy and Myosin Studies
- Congenital heart defects research
- Mitochondrial Function and Pathology
- Urological Disorders and Treatments
- Connexins and lens biology
- Digestive system and related health
- Intestinal Malrotation and Obstruction Disorders
- Barrier Structure and Function Studies
- Heart Rate Variability and Autonomic Control
- Intestinal and Peritoneal Adhesions
- Ion channel regulation and function
- Anesthesia and Neurotoxicity Research
- Receptor Mechanisms and Signaling
- Neuroscience and Neuropharmacology Research
- Tracheal and airway disorders
- Muscle metabolism and nutrition
University College London
2006-2022
UCL Australia
1971-2004
Inserm
1998
Collège de France
1996
Centre National de la Recherche Scientifique
1996
University of Szeged
1994
Lund University
1980-1993
University of Turin
1964-1971
University of London
1971
ABSTRACT Interstitial cells of Cajal (ICC) aroused much interest among neuroanatomists at the beginning century. These small cells, organized into networks, are intercalated between nerve fibers and muscle now considered by many authors to be responsible for pacemaker activity gut. Renewed in these arose recently when receptor tyrosine kinase, ckit, was shown associated with their functional activity. The embryonic origin interstitial has remained a controversial issue ever since discovery....
Objective To assess the distribution and type of nerve fibers present in human peritoneal adhesions to relate data on location size nerves with estimated age clinical parameters such as reports chronic pelvic pain. Summary Background Data Peritoneal are implicated cause abdominopelvic pain, many patients relieved their symptoms after adhesiolysis. Adhesions thought pain indirectly by restricting organ motion, thus stretching pulling smooth muscle adjacent viscera or abdominal wall. However,...
ABSTRACT In the smooth-muscle cells from guinea-pig ileum a highly developed sarcoplasmic reticulum has been observed immediately underneath plasma membrane in close relationship to caveolae intracellulares. It is suggested that smooth muscle may play similar role as skeletal muscle, constituting main intracellular store for calcium.
The size of smooth muscle cells is different in organs but varies little within the same tissue. Great changes cross-sectional area are observed distended and contracted during contraction relaxation neighbouring layers. Two basic types intercellular junction described: ( a ) attachment plaque, where myofilaments end gap wide; b nexus, adjoining come close together; or degree fusion membranes affected by preparation procedures. occurrence nexuses generally correlated with electrical...
In the myenteric plexus of rat stomach, ileum, and rectum, glial cells outnumber nerve by more than 3 to 1; they have several processes, extensively branching, which extend between, adapt themselves to, other cellular elements, constituting a very compact structure. The most prominent feature cell cytoplasm are bundles gliofilaments. No basement membrane surrounds individual cells; single is observed around whole ganglion. Morphological features do not support identification these as Schwann...