A5035447668- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystal structures of chemical compounds
- Crystallography and molecular interactions
- Nonlinear Optical Materials Research
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Metal complexes synthesis and properties
- Free Radicals and Antioxidants
- Chemical Synthesis and Analysis
- Molecular spectroscopy and chirality
- Metal-Organic Frameworks: Synthesis and Applications
- Molecular Sensors and Ion Detection
- Biochemical and Molecular Research
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Inorganic and Organometallic Chemistry
- Synthesis and Catalytic Reactions
- Chemical synthesis and pharmacological studies
- Fluorine in Organic Chemistry
- Synthesis and Biological Evaluation
- Various Chemistry Research Topics
- Carbohydrate Chemistry and Synthesis
- Synthesis of β-Lactam Compounds
Periyar Maniammai Institute of Science & Technology
2009-2021
Bharathidasan University
2002-2011
Freie Universität Berlin
2002-2003
In the crystal structures of two organic salts, namely, pyrimethamine hydrogen glutarate (1:1) 1 and formate 2, moieties are protonated at one nitrogen atoms pyrimidine rings. The carboxylate group respective anions (hydrogen formate) interacts with moiety in a near linear fashion through pair N−H···O bonds. dihedral angle between diaminopyrimidine p-chlorophenyl plane is 74.8(1)° compound 1, corresponding value 2 76.7(1)°. both compounds, centrosymmetrically paired N−H···N 2-amino member...
Pyrimethamine [2,4-diamino-5-(p-chlorophenyl)-6-ethyl-pyrimidine] (PMN) is an antifolate drug. Four new organic salts, namely, PMN hydrogen maleate (1), succinate (2), phthalate (3), and fumarate (4), have been synthesized their bonding patterns analyzed. As expected, in all the structures, moieties are protonated at one of nitrogen atoms pyrimidine rings. The carboxylate group respective anions interacts with moiety near linear fashion through a pair N−H···O bonds to form cyclic...
The present study deals with the crystal structures of four organic salts, namely, trimethoprim benzene sulfonate monohydrate 1, sulfanilate 2, p-toluene 3 and 3-carboxy-4-hydroxybenzene dihydrate 4. Trimethoprim (TMP) is protonated at one ring nitrogens pyrimidine ring. Generally, in TMP carboxylate complexes, hydrogen-bonded to group forming a cyclic fork-like bimolecular motif. In 1–3, plays role anion. compounds 1 there no pairing rings because sites are blocked by water molecules...
In the crystal structure of pyrimethamine [2,4-diamino-5-(p-chlorophenyl)-6-ethylpyrimidine], C12H13ClN4, asymmetric unit contains two crystallographically independent molecules (A and B), differing in their conformations. The dihedral angle between pyrimidine substituted phenyl plane is 74.4 (1)° molecule A 82.4 B. Molecule linked with B through a pair N—H⋯N hydrogen bonds on one side another other side. Thus, there supramolecular ribbon, consisting arranged an alternating manner. Two...
In this study, (R)-9-(2-hydroxy propyl)adenine (HPA) is the molecule of interest for investigation. The XRD from single crystal HPA has been used to extract its structural features. Since crystallised in a non-centro symmetric space group P2
In the crystal structure of title zwitterion, C5H11N5S, mol-ecules are linked via N-H⋯N hydrogen bonds, forming zigzag chains propagating along [010]. The by C-H⋯S two dimensional networks lying parallel to (001).
In the title complex, diaquadinitrato[2-(4-thiazolyl)benzimidazole]copper(II), [Cu(NO3)2(C10H7N3S)(H2O)2], Cu atom has a distorted octahedral geometry. Thiabendazole [2-(4-thiazolyl)benzimidazole] acts as neutral bidentate chelate, coordinating through imidazole and thiazole N atoms. The equatorial positions are occupied by two atoms of thiabendazole molecule O water molecules. axial nitrate ions acting monodentate ligands. complex units further self-assembled into...
The crystal structure investigation of the title compound 4-((pyrrolidin-1-ylsulfonyl) methyl)aniline (PSMA) C11H16N2O2S shows that molecule is essentially coplanar with a dihedral angle 26.70(14)°between pyrrolidine and benzene rings. A pair strong N-H···O hydrogen bonds produces continuous two-dimensional sheets R22(18) ring motifs. also features weak C-H···π interaction resulting in three-dimensional network. Density functional theory (DFT) calculations reveal experimental calculated...
In the title salt, C4H7N4O(+)·C7H7O3S(-), 2,6-di-amino-4-oxo-1,3-di-hydro-pyrimidin-1-ium cation inter-acts with sulfonate group of p-toluene-sulfonate anion via a pair N-H⋯O hydrogen bonds, forming hetero-synthon R 2 (2)(8) that mimics role carboxyl-ate. The self-assembled cations form homo-synthon (1)(6) motif which is further linked bonds to generate an 3 (2)(10) ring motif. three motifs are fused together and extended as supra-molecular ribbons along b-axis direction. Adjacent annulus, 4...
In the title compound, C 13 H 12 ClN 2 , indole moiety and chloroalkyl substituent are nearly coplanar, making a dihedral angle of 1.27 (10)°. crystal, supramolecular sheet parallel to ab plane is generated via weak C—H...Cl hydrogen bonds, aromatic π–π stacking [centroid–centroid distances 3.5563 (13) 3.6792 Å] C—H...π interactions.
The complete molecule of the title compound [systematic name: 2,2′-(5-methyl-1,3-phenylene)bis(2-methylpropanenitrile)] is generated by a crystallographic twofold axis, which leads to disorder H atoms on methyl group attached benzene ring. dihedral angle between ring and nitrile 26.2 (2)°. In crystal, pairs weak C—H...π interactions link molecules into dimers. absorbs at 212 nm as result π–π* transition.