A5020610405- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- Bone health and treatments
- Bone Metabolism and Diseases
- Connective tissue disorders research
- Knee injuries and reconstruction techniques
- Head and Neck Cancer Studies
- Laser Applications in Dentistry and Medicine
- Cancer, Hypoxia, and Metabolism
- Selenium in Biological Systems
- Colorectal Cancer Treatments and Studies
- Epigenetics and DNA Methylation
- Cancer Immunotherapy and Biomarkers
- MXene and MAX Phase Materials
- Cardiac and Coronary Surgery Techniques
- Bone health and osteoporosis research
- Cancer-related gene regulation
- Biosensors and Analytical Detection
- Electrospun Nanofibers in Biomedical Applications
- Advanced Breast Cancer Therapies
- Connective Tissue Growth Factor Research
- Osteoarthritis Treatment and Mechanisms
- Tissue Engineering and Regenerative Medicine
- Additive Manufacturing and 3D Printing Technologies
- Mesenchymal stem cell research
Southern Medical University
2022-2025
Nanfang Hospital
2022
Abstract Anti‐virulence therapy that interferes with bacterial communication, known as “quorum sensing (QS)”, is a promising strategy for circumventing resistance. Using nanomaterials to regulate QS in anti‐virulence has attracted much attention, which mainly attributed unique physicochemical properties and excellent designability of nanomaterials. However, dynamic multistep process, there are significant differences the specific regulatory mechanisms related influencing factors different...
The repair of critical-sized bone defects continues to pose a challenge in clinics. Strontium (Sr), recognized for its function metabolism regulation, has shown potential repair. However, the underlying mechanism through which Sr2+ guided favorable osteogenesis by modulating macrophages remains unclear, limiting their application design biomaterials. Herein, Sr-incorporated bioactive glass (SrBG) was synthesized further investigation. release Sr ions enhanced immunomodulatory properties and...
The repair of bone defects in the elderly individuals is significantly delayed due to cellular senescence and dysfunction, which presents a challenge clinical settings. Furthermore, there are limited effective methods available promote older individuals. Herein, melatonin-loaded mesoporous bioactive glasses microspheres (MTBG) were successfully prepared based on their properties. aged rats was accelerated by enhancing mitochondrial function through sustained release melatonin ions. MTBG...
An imbalanced system of angiogenesis-osteoblasts-osteoclasts is regarded as the main factor in bone remodeling dysfunction diseases or osseointegration loss. Osteoclast precursors are key cells that accelerate bone-specific angiogenesis and maintain normal osteoblast osteoclast function. Graphene oxide an effective scaffold surface modification agent with broad application prospects tissue engineering. However, effect graphene on interaction between osteoclasts has not yet been elucidated....
Abstract The rapid and efficient bone regeneration is still in unsatisfactory outcomes, demonstrating alternative strategy molecular mechanism necessary. Nanoscale biomaterials have shown some promising results enhancing regeneration, however, the detailed interaction between nanomaterial cells/tissue formation not clear. Herein, a molecular‐based inorganic–organic poly(citrate‐siloxane) (PCS) reported which can rapidly enhance osteogenic differentiation through special with cellular surface...
Endochondral ossification (ECO) plays an integral part in bone augmentation, which undergoes sequential processes including mesenchymal stem cells (MSC) condensation, chondrocyte differentiation, hypertrophy, and mineralized formation. Thus, accelerating these steps will speed up the osteogenesis process through ECO. Herein, inspired by marine mussels' adhesive mechanism, a bioactive glass-dopamine (BG-Dopa) hydrogel was prepared distributing micro-nano BG to aldehyde modified hyaluronic...