Alejandra Maciel

ORCID: 0000-0003-4456-2905
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About
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Research Areas
  • Treatment of Major Depression
  • Cervical Cancer and HPV Research
  • Health Systems, Economic Evaluations, Quality of Life
  • Heart Rate Variability and Autonomic Control
  • Non-Invasive Vital Sign Monitoring
  • Hemodynamic Monitoring and Therapy
  • Attention Deficit Hyperactivity Disorder
  • Cancer-related Molecular Pathways
  • Head and Neck Cancer Studies
  • Pharmacogenetics and Drug Metabolism
  • Cancer Diagnosis and Treatment
  • Sleep and related disorders
  • Global Cancer Incidence and Screening
  • Statistical Methods in Clinical Trials
  • Multiple and Secondary Primary Cancers
  • Cancer Cells and Metastasis
  • Child and Adolescent Psychosocial and Emotional Development
  • Health and Wellbeing Research
  • Retinal Diseases and Treatments
  • Sleep and Wakefulness Research
  • Breast Cancer Treatment Studies
  • Genital Health and Disease
  • Tryptophan and brain disorders
  • Radiomics and Machine Learning in Medical Imaging
  • Breast Implant and Reconstruction

Google (United States)
2019-2025

Universidad del Salvador
2019

AltheaDx (United States)
2017-2018

Bernardino Rivadavia Natural Sciences Museum
1997

The objective of this study was to evaluate the effect pharmacogenetics-guided treatment on patients diagnosed with depression and/or anxiety, in a diverse set clinical settings, as compared standard care. trial design followed prospective, randomized, subject- and rater-blinded approach enrolling 685 from providers specializing Psychiatry, Internal Medicine, Obstetrics & Gynecology, Family Medicine. NeuroIDgenetix® test uses genetic variant panel ten genes, along concomitant medications,...

10.1016/j.jpsychires.2017.09.024 article EN cc-by-nc-nd Journal of Psychiatric Research 2017-09-23

The burden of depression significantly impacts the patient, health care system, and society, at large. Medication management guided by pharmacogenetics has been shown to increase therapeutic efficacy improve symptoms in patients diagnosed with depression, but limited data are available on cost savings pharmacogenetic-guided interventions outside psychiatric clinical specialties. Our study utilizes published costs patient outcome model economic impact treatment for a variety settings....

10.2147/ndt.s145046 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2018-01-01

Abstract Background Measuring vital signs plays a key role in both patient care and wellness, but can be challenging outside of medical settings due to the lack specialized equipment. Methods In this study, we prospectively evaluated smartphone camera-based techniques for measuring heart rate (HR) respiratory (RR) consumer wellness use. HR was measured by placing finger over rear-facing camera, while RR via video participants sitting still front front-facing camera. Results study 95 (with...

10.1038/s43856-022-00102-x article EN cc-by Communications Medicine 2022-04-12

Background Insomnia increases in frequency as women approach and pass through menopause. Studies have not shown acupuncture efficacy for insomnia postmenopausal women.Objectives The aim of this study was to evaluate the effectiveness therapy on sleep parameters, depression symptoms quality life with insomnia.Methods This included 18 aged 50–67 years old. Participants had a body mass index ≤ 30 kg/m2, presented diagnosis according DSM-IV criteria, experienced at least 1 year amenorrhea...

10.3109/13697137.2012.698432 article EN Climacteric 2012-01-01

Recent clinical trials indicate that pharmacogenetic-guided treatment of major depressive disorder (MDD) results in higher response rates by genetically matching patients to medications and avoiding a trial-and-error process.To evaluate the cost-effectiveness pharmacogenetic test (IDGx) has demonstrated effectiveness compared with standard care (SOC) medication management among varied MDD severity.Data from large prospective, randomized controlled trial treatment-naive or inadequately...

10.18553/jmcp.2018.24.8.726 article EN Journal of Managed Care & Specialty Pharmacy 2018-07-30

Article Abstract Objective: Pharmacogenetic testing holds promise as a personalized medicine tool by permitting individualization of pharmacotherapy in accordance with genes influencing therapeutic response, side effects, and adverse events. The authors evaluated the effect on outcomes for patients diagnosed neuropsychiatric disorders pharmacogenetics (PGx)-guided treatment compared to usual standard care. Methods: This was prospective, randomized study 237 at an outpatient community-based...

10.4088/pcc.16m02036 article EN The Primary Care Companion For CNS Disorders 2017-03-16

The response to therapeutics varies widely in patients with depression and anxiety, making selection of an optimal treatment choice challenging. IDgenetix®, a novel pharmacogenomic test, has been shown improve outcomes by predicting the likelihood different psychotherapeutic medications.The objective this study was estimate cost effectiveness implementing test (IDgenetix®) guide choices and/or anxiety compared as usual from US societal perspective.We developed discrete event simulation...

10.1007/s40273-017-0587-0 article EN cc-by-nc PharmacoEconomics 2017-11-06

Background. Human papillomavirus (HPVs) types 6 and 11, are frequently found in non‐malignant anogenital condylomas laryngeal papillomas. However, an ongoing epidemiological study Argentina which 163 aero‐respiratory cancer biopsies were analyzed, several cases infected with low‐risk HPVs could be detected. Methods. Tumor samples analyzed by Southern blot hybridization, using 6, 16, 18, 30, 31, 33 35 as probes, polymerase chain reaction (PCR) type‐specific primers probes. Results. Four...

10.1111/j.1600-0412.1997.tb07858.x article EN Acta Obstetricia Et Gynecologica Scandinavica 1997-03-01

Background. Human papillomavirus (HPVs) types 6 and 11, are frequently found in non-malignant anogenital condylomas laryngeal papillomas. However, an ongoing epidemiological study Argentina which 163 aero-respiratory cancer biopsies were analyzed, several cases infected with low-risk HPVs could be detected. Methods. Tumor samples analyzed by Southern blot hybridization, using 6, 16, 18, 30, 31, 33 35 as probes, polymerase chain reaction (PCR) type-specific primers probes.Results. Four...

10.3109/00016349709048154 article EN Acta Obstetricia Et Gynecologica Scandinavica 1997-01-01

Abstract Measuring vital signs plays a key role in both patient care and wellness, but can be challenging outside of medical settings due to the lack specialized equipment. In this study, we prospectively evaluated smartphone camera-based techniques for measuring heart rate (HR) respiratory (RR) consumer wellness use. HR was measured by placing finger over rear-facing camera, while RR via video participants sitting still front front-facing camera. study 95 (with protocol that included...

10.21203/rs.3.rs-620411/v1 preprint EN cc-by Research Square (Research Square) 2021-06-22

Abstract Measuring vital signs plays a key role in both patient care and wellness, but can be challenging outside of medical settings due to the lack specialized equipment. In this study, we prospectively evaluated smartphone camera-based techniques for measuring heart rate (HR) respiratory (RR) consumer wellness use. HR was measured by placing finger over rear-facing camera, while RR via video participants sitting still front front-facing camera. study 95 (with protocol that included...

10.1101/2021.03.08.21252408 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-03-12
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