The labeling of cell surface receptors by fluorescent markers is an established method for the identification phenotype in both research and clinical settings. Fluorescence dye has inherent constraints, most notably upper limit labels per that may be probed using a single excitation source, addition to physical number broad emission spectra can distinctly collected within visible wavelength region. SERS potential mitigate these shortfalls. Herein, antibody-targeted, PEG-coated...

Trace vapor detection of hydrogen peroxide (H2O2) represents a practical approach to nondestructive peroxide-based explosives, including liquid mixtures H2O2 and fuels energetic derivatives, such as triacetone triperoxide (TATP), diacetone diperoxide (DADP), hexamethylene diamine (HMTD). Development simple chemical sensor system that responds with high reliability sufficient sensitivity (reactivity) remains challenge. We report fluorescence ratiometric molecule, diethyl...

We report fabrication, characterization, and potential applications of polyoxometalate (POM)/ionic liquid (IL) supramolecular spheres in water for the first time. These have highly ordered structures show excellent reversible self-assembly tunable photoluminescence properties, which can be manipulated by adjusting pH aqueous solution. Specifically, formation POM/IL results quenching fluorescence emitted Eu-POM because hopping d1 electron POM molecule is blocked hydrogen bond existing between...

AIEgen-functionalised mesoporous silica nanoparticles can be used for the detection of explosives and antibiotics based on a FRET mechanism.

Load conductive component onto textiles via coating method is a simple and facile fabrication process to prepare flexible smart wearable device. However, this functional textile will suffer significant damage after washing or mechanical wear, which hindered its application. In study, polydopamine (PDA) was used as an interfacial agent enhance the combination between carbon nanotubes (CNTs) cotton fiber fabricated highly fabric. Furthermore, hydrophobic material...

Keggin-type polyoxometalate (POM), phosphotungstic acid (H3PW12O40), was encapsulated by an oppositely charged COOH-functionalized surface active ionic liquid (SAIL), N-decyl-N′-carboxymethyl imidazolium bromide ([N-C10, N′-COOH-Im]Br), with the assistance of self-assembly (ISA) process in aqueous environment. The as-prepared POM/SAIL material possesses multiple properties, including reversible pH-response and renewable catalyst for dye degradation. Specifically, POM-based hybrid materials...

In this work, we fabricate two types of hierarchical microspheres, i.e., one coassembled from fluorene-based oligomers (1 and 2) self-assembled a oligomer (1), for ultrasensitive selective detection trace sulfur mustard (SM) vapor. On the basis distinct fluorescence responses 1-2 individual 1 microspheres that originate differential noncovalent interactions between analytes these sensors, SM vapor can be ultrasensitively detected (30 ppb) easily discriminated various sulfides other potential...

Donor-acceptor nanofibril composites have been fabricated, and the dependence of their photocurrent response on structure morphology donor part has systematically investigated. The were composed template nanofibers, assembled from an electron acceptor molecule, perylene tetracarboxylic diimide (PTCDI), onto which (through drop-casting) various molecules (D1-D4) coated. same π-conjugated core, but different side groups. Due to groups, four showed distinctly propensity for intermolecular...

γ radiation causes self-assembly of sensor molecules into a nanofibril structure, enabling stimuli-responsive sensing based on fluorescence and photoconductivity modulation.

Tea is the second widely consumed beverage next to water. drinking one of important pathways for human exposure organonphosphorus pesticide. Consequently, incidence pesticide residues and risk assessment should be clear. In this study, level in 810 Chinese teas manufactured between 2010–2013 was investigated using gas chromatography coupled with tandem mass spectrometry a flame photometric detector. Incidence occurred frequency 29% average concentration 93 μg kg−1. The residue levels varied...

In this work, we develop fluorescent hierarchical nanofiber bundles 1, which involve the internanofiber hydrogen-bonding interactions, for rapid and sensitive detection of diethyl chlorophosphate (DCP) vapor. First, strength can be weakened by photoexcitation, thereby increases spacing decreases fluorescence intensity. Then, when exposed to trace DCP vapor, strong interactions between hydroxyl groups on nanofibers effectively retighten enhance as signal. contrast, interferences, such common...

In this work, we develop a sequential self-assembly approach to fabricate interpenetrated binary supramolecular nanofibers consisting of carbazole oligomer 1-cobalt(II) (1-Co2+) coordination and 2 for the sensitive detection six classes explosives. When exposed peroxide explosives (e.g., H2O2), Co2+ in 1-Co2+ can be reduced Co+ that transfer an electron excited thereby quench their fluorescence. On other hand, when five explosives, basis distinct fluorescence quenching mechanisms,...

Formaldehyde is widely utilized across various industries such as food, textiles, and leather, yet its presence raises significant health concerns due to irritation carcinogenicity. Numerous methods have been developed probe it in solution gas states. Among them, absorption spectroscopy-based commonly employed. However, these require complex preprocessing for colored solutions avoid interference. In response this challenge, a novel interference-resistant detection kit leveraging...

The development of fluorescent heterocyclic compounds bearing s -triazine and cyclotriphosphazene scaffolds for researching the structure–property relationship high-efficiency amine sensing is still challenging.

Emodin is one of the main active ingredient Rheum palmatum, and has anti-inflammatory, anti-bacterial, anti-viral other effects. In recent years, it arouse concern since a significant anti-tumor effect with low toxicity. this paper we mainly report anti-cancer effects emodin according to studies past five including four parts such as inhibit tumor growth, migration invasion, enhance efficacy combination therapy, increase chemosensitivity attenuated side We hope that our work may provide...

Huperzine A (HupA), an alkaloid isolated from the Chinese club moss , is a reversible inhibitor of cholinesterases which cross blood-brain barrier and show high specificity for acetylcholinesterase (AChE). However, HupA induces unwanted side effects in effective dose against nerve agent poisoning. In present study, HupA–loaded poly (lactide-co-glycolide) nanoparticles (HupA-PLGA-NP) were prepared using O/W emulsion solvent evaporation method. The results SEM demonstrated that HupA-PLGA-NP...

Soman has been shown to be highly neurotoxic and can easily degraded produce pinacolyl methylphosphonate acid (PMPA). Thus, the perniciousness of PMPA deserved serious attention after soman was exposed environment. However, toxicity not clearly elucidated date. In this regard, objective study determine if could pose an environmental risk exposure a water study, bioaccumulation assessments were carried out on zebrafish. Histological examination used assess in zebrafish revealed that chronic...

Surface-enhanced Raman spectroscopy (SERS) has attracted lots of interest in academic and industrial fields recent years. The improvement long-time sensitivity repeatability is highly demanded by the on-site applications. Herein, we present an expedient SERS strip tactic with these desired advantages. Specifically, utilized outstanding stability colloidal particles to maintain materials during storage. Upon usage, rapidly prepared on-site, then targets were sampled a dip-coating heating...

This work aimed to assess whether mitochondrial damage in the liver induced by subacute soman exposure is caused peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1α) and PGC-1α regulates respiratory chain damage. Toxicity mechanism research may provide theoretical support for developing anti-toxic drugs future. First, a animal model was established male Sprague-Dawley (SD) rats subcutaneous injection. Then, biochemically evaluated, acetylcholinesterase (AChE)...