- Geophysical and Geoelectrical Methods
- Seismic Waves and Analysis
- Geophysical Methods and Applications
- Cutaneous Melanoma Detection and Management
- NMR spectroscopy and applications
- Melanoma and MAPK Pathways
- Cancer Immunotherapy and Biomarkers
- Geochemistry and Geologic Mapping
- Nonmelanoma Skin Cancer Studies
- Cancer Cells and Metastasis
- Seismic Imaging and Inversion Techniques
- Groundwater flow and contamination studies
- Immunotherapy and Immune Responses
- CAR-T cell therapy research
- Earthquake Detection and Analysis
- Metastasis and carcinoma case studies
- Mineral Processing and Grinding
- Pleural and Pulmonary Diseases
- Electrokinetic Soil Remediation Techniques
- Immune Cell Function and Interaction
- Breast Cancer Treatment Studies
- Immune cells in cancer
- Ovarian cancer diagnosis and treatment
- Optical Coherence Tomography Applications
- Cancer Research and Treatments
Botkin Hospital
2023-2025
City Clinical Hospital
2022-2025
Peoples' Friendship University of Russia
2020-2025
Russian New University
2025
St Petersburg University
2012-2024
Bauman Moscow State Technical University
2019-2024
State Healthcare Institution "Regional Clinical Oncological Dispensary"
2024
MosvodokanalNIIproject Institute (Russia)
2023
Moscow Clinical Scientific Center
2017-2021
Kazan State Technical University named after A. N. Tupolev
2018
ABSTRACT Over the last 15 years significant advancements in induced polarization (IP) research have taken place, particularly with respect to spectral IP (SIP), concerning understanding of mechanisms phenomenon, conduction accurate and broadband laboratory measurements, modelling inversion data for imaging purposes increasing application method near‐surface investigations. We summarize here current state science SIP applications describe which aspects still represent open issues should be...
Abstract Two different equations, both of which are often called ‘the Cole–Cole equation’, widely used to fit experimental Spectral Induced Polarization data. The data compared on the basis fitting model parameters: chargeability, time constant and exponent. difference between above two equations (the equation proposed by Cole brothers Pelton's equation) is manifested in one parameters, constant. an inverse peak angular frequency imaginary conductivity, while depends chargeability exponent...
To study the predictive role of tumor-associated neutrophils in early luminal HER2-negative breast cancer. This is a retrospective conducted on 60 women cases aged from 31 to 79 years underwent surgery for ductal cancer tertiary care centre. We first estimated basic morphological signs: tumor size, grade (by Nottingham Histologic Score), infiltrating lymphocytes (TILs), Lymphovascular invasion, hormonal receptors status, proliferative index, and regional lymph nodes metastasis. The...
We consider the case of a cylindrical cored specimen saturated argillaceous sediment located between two reservoirs filled with an electrolyte. One boundaries sample is submitted to sharp pressure (or salinity change). The migration resulting saline) front through core responsible for apparition electrical field, which called streaming potential (the diffusion gradient, respectively). temporal variation this field recorded Ag/AgCl nonpolarizable electrodes and used monitor evolution...
We studied artificial ore models that contained galena, pyrite, magnetite, graphite and cryptomelane with the time domain induced polarization technique. The were mixtures of sand metallic-type, electronically conductive mineral particles. varied volumetric content particles, their composition average grain size, as well pore water salinity. Based on Debye decomposition approach, we obtained relaxation distributions, which peaks. From these total chargeability peak time. correlated...
We studied the electrical induced polarization (IP) response of simple multiphase porous systems by conducting time‐domain (TD) IP measurements on two different groups sieved quartz samples: sands containing air in unsaturated pores and where were filled with kerosene. The analyzed chargeability vs. water content relationship showed an extreme behavior. resistivity exhibited distinct power law regions characterized values power‐law exponents. Quartz–water–air quartz–water–kerosene samples...
We investigated electrical and physical–chemical properties of six sandstone samples with contrasting mineralogical characteristics hydraulic conductivity varying in a wide range. The data were obtained from time domain spectral induced polarization (IP) measurements.
We propose an algorithm for inverting time domain induced polarization data to a relaxation distribution. The is based on the (Tikhonov) regularized solution of 2nd kind Fredholm integral equation. test synthetic data, and show its robustness noise level, typical laboratory measurements. also that, inversion purpose, must be obtained with different current wavelengths. then experimental recently brine-saturated medium-grained quartz sand (average grain diameter 4 × 10−4 m), mixtures. For...
The study of electrical signals associated with groundwater flow is a powerful method to determine, in non-invasive way, the distribution hydraulic heads aquifers, hence conductivity and storativity. Experimental (self-potential, SP) pumping test an unconfined aquifer were reproduced numerical model based on finite-difference method. For simplicity, we assumed axial symmetry around well. We assessed equivalent specific storage by fitting piezometric levels obtained course against synthetic...
An infiltration test was performed from a ditch with the purpose of monitoring evolution piezometric levels using self‐potential measurements made at ground surface. We used set 18 piezometers and network 41 nonpolarizable (Pb/PbCl 2 ) electrodes. The variations signals are linearly correlated to level changes an apparent voltage coupling coefficient −5.5 ± 0.9 mV m −1 . measured, independently this test, three material properties entering macroscopic field equations. They resistivity...
SUMMARY Clay minerals are extensively used in a wide range of applications. In particular, clay-bearing formations considered as suitable radioactive waste repository. Electrical resistivity tomography is an appropriate tool to monitor the properties locations. However, inherent drawback conventional survey its ambiguity distinguishing between effects groundwater salinity, clay content and porosity. A discrimination can be achieved on basis induced polarization method that provides complex...
Skin melanoma is one of the most malignant tumors and responsible for 70.3% deaths in group skin cancers Russian Federation. characterized by a steady increase incidence among working-age population, both Russia abroad (annual about 3–4%). At moment, stages I-II melanoma, practitioners have been using only clinical (clinical form localization, gender, age, etc.) standard pathomorphological prognostic factors many years. For thin presence ulceration, Breslow thickness, mitotic index,...
Interest in melanoma precursors, or melanoma-sensitive skin nevi, has not lost its relevance for many years due to the steady increase of morbidity recent decades among population (annual growth up 5%). Skin occupies a leading place causes death from all malignant tumors (up 70%). We aimed systematize, summarize scientific and practical data world Russian literature on congenital melanocytic dysplastic nevi syndrome hereditary FAMMM (familial atypical melanoma) determine their relation risk...
BACKGROUND: The proportion of pancreatic cancer remains high in the overall incidence. Pancreatic ductal adenocarcinoma is a highly aggressive and lethal tumor. AIM: To evaluate microvascular endothelial function patients undergoing head surgery to establish correlation with surgical outcomes. MATERIALS AND METHODS: A prospective observational randomized study was conducted from 2009 2022. included two cohorts: healthy subjects (control group, n=40) diagnosed (patient n=95) who underwent...
BACKGROUND: The sensitivity of transthoracic biopsy under CT navigation in the verification malignant lung tumors ranges from 74 to 90%. Diagnostic for detection neoplasms is lower small (3 cm), and about 15-30% biopsies does not allow obtain informative material. An augmented reality robotic system percutaneous control computed tomography, providing tracking position needle during procedure, allowing more accurate foci lungs. In this article, we present our own experience using a when...
Introduction. Ovarian metastases are characterized by low sensitivity to systemic therapy and often associated with rapid progression poor prognosis. Given the of from cancers gastrointestinal tract therapy, optimal choice treatment strategy for ovarian is one key problems in modern oncology. The aim work was evaluate effectiveness bilateral adnexectomy combination chemotherapy patients tract. Aim. this study metastatic lesions originating cancer. Materials methods. included 58 aged 37 77...
According to the International Agency for Research on Cancer GLOBOCAN (Cancer Today), breast cancer ranks first in structure of mortality from among women. In recent decades, there has been a steady trend treatment minimize volume radical surgical order improve quality patients lives and comply with principles oncological adequacy. A sentinel lymph node biopsy (SLNB) is an alternative axillary lymphatic dissection clinically intact regional nodes (cN0). This allows avoid such formidable...
Reusable electronic tongues (e-tongues), which rely on an array of electrodes to record electrochemical responses from complex mixtures and advanced pattern recognition techniques decipher them, are popular sensors...
Anaplastic thyroid cancer (ATC) is a rare form of malignancy with high aggressiveness and an extremely poor prognosis. Currently, two main models ATC origin are considered: anaplastic carcinoma arises either from patient’s pre-existing highly differentiated tumor cells through dedifferentiation, or de novo . Between 20 50% have activating V600E mutations in the BRAF gene. The combination targeted drugs dabrafenib trametinib has shown promising results number cancers gene, including cohort...