- Bone health and treatments
- Liver Disease Diagnosis and Treatment
- Estrogen and related hormone effects
- Global Cancer Incidence and Screening
- Ultrasound Imaging and Elastography
- Liver physiology and pathology
- Pharmacogenetics and Drug Metabolism
- Hepatitis C virus research
- Liver Diseases and Immunity
- Bone health and osteoporosis research
- Pharmaceutical Practices and Patient Outcomes
- Photoacoustic and Ultrasonic Imaging
- Pharmaceutical studies and practices
- Diabetes Treatment and Management
- BRCA gene mutations in cancer
- Ultrasonics and Acoustic Wave Propagation
- Drug-Induced Hepatotoxicity and Protection
- Economic and Financial Impacts of Cancer
- Medical Imaging Techniques and Applications
- Ultrasound and Hyperthermia Applications
- Pancreatic function and diabetes
- AI in cancer detection
- Vascular anomalies and interventions
- Systemic Lupus Erythematosus Research
- Temporomandibular Joint Disorders
University of Osijek
2017-2025
Institute of Public Health Osijek-Baranja County
2021-2025
Tauern Hospital Zell am See
2021
Klinički bolnički centar Osijek
2008
To determine the levels of Wnt inhibitors in patients treated with aromatase (AIs) prior to therapy and investigate their association bone mineral density (BMD) lifestyle parameters. 137 breast cancer were divided into a group 1 mg anastrozole w/o therapy. Serum concentrations sclerostin dickkopf1 (DKK1) measured by ELISA. BMD was dual-energy X-ray absorptiometry (DXA). Lifestyle factors investigated self-reported questionnaire. Sclerostin significantly higher AI-treated (31.8 pmol/L vs....
Background and Objectives: In recent years, numerous studies have investigated analyzed the levels of molecular biomarkers temporomandibular disorders (TMD) from various tissue samples body fluids. However, no study has gingival crevicular fluid (GCF) in TMD patients. The purpose this was to determine concentrations pro-inflammatory cytokines GCF before after stabilization splint (SS) therapy patients with painful TMD, investigate whether SS administration causes changes cytokines. An...
The aim of this study was to evaluate whether the combination B-mode ultrasound, elastography score (ES) and strain ratio (SR) improves diagnostic performance with respect breast lesions. One hundred thirty lesions were prospectively evaluated by ultrasound elastography, followed fine-needle aspiration cytology/biopsy in 117 woman who scheduled for regular BUS. median ES (4.5 vs. 2.9, p < 0.001) SR (4.9 2.3, significantly higher malignant than benign A sensitivity 90.5% specificity 93.2%...
Prescribing medications is one of the most common medical decisions that made by primary care providers (PCPs). In Republic Croatia, PCPs hold a key position in prescribing and evaluating are provided for patients. Accordingly, providing advice patients regarding potential adverse drug reactions (ADRs) drug-drug interactions (DDIs) frequently responsibility PCPs. The aim current study was to assess knowledge, attitudes, counseling practices effects. After enrolling 195 were selected at...
Background and Objectives: Periodontitis is marked by the destruction of alveolar bone. Sclerostin (SOST) dickkopf-1 (DKK-1) act as inhibitors Wingless-type (Wnt) signaling pathway, a key regulator bone metabolism. Recent studies have suggested that statins play role in resorption formation influencing Wnt signaling. The aim this study was to determine levels SOST DKK-1 periodontal patients with without peroral treatment their therapy. Materials Methods: A total 79 diagnosed periodontitis...
With around one billion of the world&#039;s population affected, era Metabolic-associated fatty liver disease (MAFLD) pandemic has entered global stage. MAFLD is a chronic progressive with accompanying metabolic disorders such as type 2 diabetes mellitus and obesity which can progress asymptomatically to cirrhosis subsequently hepatocellular carcinoma (HCC), for which, date there almost no approved pharmacologic options. Because very complex etiology it affects also extrahepatic organs,...
Breast density (BD) reduces sensitivity of mammography, and is a strong risk factor for breast cancer (BC). Data about women's awareness knowledge BD are limited. Our aim to examine whether the information disclosure among women without BC related their factors. We examined self-reported perception its association level health literacy. A cross-sectional, single site study included 263 Croatian who had mammographic examination. were collected by interviews using questionnaires validated...
Single nucleotide polymorphism (SNP) in genes encoding drug-metabolizing enzymes (DME) could have a critical role individual responses to anastrozole. Frequency of CYP3A4*1B, CYP3A5*3 and UGT1A4*2 SNPs 126 Croatian breast cancer (BC) patients possible association with anastrozole-induced undesirable side effects were analyzed. Eighty-two postmenopausal estrogen receptor (ER)-positive BC treated anastrozole 44 ER-positive before hormonal adjuvant therapy included the study. Genomic DNA was...
Breast sonoelastography is a relatively novel ultrasound (US) method that enables estimation of tissue stiffness to estimate the elasticity normal breast and seek correlate it with well-known cancer risk factors. Two hundred women different age were included in study completed questionnaire about personal, familiar, reproductive history. Glandular fatty all quadrants was measured by shear wave elastography (SWE). Mean elastographic values calculated compared personal history Elasticity...
Shear wave elastography (SWE) is a type of ultrasound with which the elastic properties breast tissues can be quantitatively assessed. The purpose this study was to determine impact different regions interest (ROI) and lesion size on performance SWE in differentiating malignant lesions. included 150 female patients histopathologically confirmed Minimal (Emin), mean (Emean), maximal (Emax) modulus elasticity ratio (e-ratio) values were measured using circular ROI 2, 4 6 mm diameters lesions...
The increase of breast cancer (BC) incidence has drawn attention to BC risk as means reducing mortality and morbidity the disease. aim this study was determine accuracy perception, evaluate factors that affect perception assess correlation between attitudes towards chemoprevention. A cross-sectional included total 258 women with average high-risk for according Breast Cancer Risk Assessment Tool (BCRAT). All data were collected by face-to-face interview three trained 6th year medical school...
Breast cancer (BC) is a highly heterogeneous disease. Aim was to evaluate imaging features of triple negative breast cancers (TNBC) in comparison non-TNBC. We reviewed data 30 patients who had been diagnosed as having TNBC and 37 with non-TNBC (control group) using criteria described for mammography (MMG), ultrasound (US) magnetic resonance (MRI) Imaging-Reporting Data System (BI-RADS) lexicon image interpretation. Age patients, size tumor, multifocality, histological type, tumor grade...