A5076986738- Breast Cancer Treatment Studies
- Cancer Cells and Metastasis
- Estrogen and related hormone effects
- Endometrial and Cervical Cancer Treatments
- HER2/EGFR in Cancer Research
- Cell death mechanisms and regulation
- Cancer-related Molecular Pathways
- Ovarian cancer diagnosis and treatment
- Cancer Genomics and Diagnostics
- Breast Lesions and Carcinomas
- Nuclear Structure and Function
- Cancer Risks and Factors
- Mesenchymal stem cell research
- Ubiquitin and proteasome pathways
- Cervical Cancer and HPV Research
- Peptidase Inhibition and Analysis
- Drug Transport and Resistance Mechanisms
- Global Cancer Incidence and Screening
- RNA Research and Splicing
- Mechanisms of cancer metastasis
- Tissue Engineering and Regenerative Medicine
- Uterine Myomas and Treatments
- Epigenetics and DNA Methylation
- BRCA gene mutations in cancer
- Cell Adhesion Molecules Research
Universidad de Valladolid
2016-2025
Kreiskliniken Reutlingen
2020-2023
German Cancer Research Center
1989-2022
Heidelberg University
2022
Universidad Rey Juan Carlos
2006-2019
Medical University of Vienna
2018
Marqués de Valdecilla University Hospital
1987-2013
Universidad de Cantabria
2010-2013
Addis Ababa University
2011
Washington University in St. Louis
2010
// Noemí Eiró 1,5,* , Juan Sendon-Lago 2,* Samuel Seoane 2 María A. Bermúdez Maria Luz Lamelas 1 Tomás Garcia-Caballero 3 José Schneider 4,5 Roman Perez-Fernandez 2,5 and Francisco J. Vizoso 1,5 Unidad de Investigación, Fundación Hospital Jove, Gijón, Spain Departamento Fisiología-CIMUS, Universidad Santiago Compostela, Ciencias Morfológicas, 4 Rey Carlos, Facultad la Salud, 5 para Investigación con Células Madre Uterinas (FICEMU), * These authors contributed equally to this work...
Abstract In a recent report, it has been postulated that the ubiquitous RBM proteins might constitute novel family of apoptosis modulators. We measured expression X‐chromosome genes ( RBMX , RBM3 and RBM10) in 122 breast cancers by means differential RT‐PCR. Using same method, we also studied apoptosis‐related Bcl‐2 Bax . Markers hormone dependence (estrogen progesterone receptors), proliferation (Ki67 DNA‐ploidy), angiogenesis (VEGF CD105), as well oncogene (c‐erb‐B2), tumor suppressor gene...
Abstract The nuclear pore complex protein Nup88 is overexpressed in tumor cells. Immunohistochemical studies have shown that this overexpression linked to higher aggressiveness of colorectal carcinoma and enhanced metastatic potential melanoma However, the antibodies so far developed against drawback recognizing a number other, up now unspecified antigens besides Nup88. For reason, we devised present study on expression at mRNA level. RNA was extracted from fresh tissue corresponding 122...
Abstract Background Low birth weight rates are increasing in both developed and developing countries. Although several maternal factors have been identified as associated with low weight, little is known of economic or organization influencing this increase. This study aims to ascertain the twenty-first century relationships between contextual country rates. Methods We analyse trends Organisation for Economic Co-operation Development (OECD) Data from 2000 2015 were obtained OECD data base....
Tobacco use is a recognized cofactor risk for cervical cancer induced by high-risk Human Papilloma Virus (HR-HPV). This study aimed to evaluate the specific influence of tobacco on colposcopic examination results in women infected HR-HPV. HR-HPV-positive undergoing loop electrosurgical excision procedure (LLETZ) after were considered this study. A total 819 patients from regional screening program included, whom 320 smokers and 499 non-smokers. Smokers significantly younger (41.1 vs. 43.8,...
Mammaglobin (h-MAM) is expressed mainly by breast epithelial cells, and this feature has been used to detect circulating cancer cells occult metastases in sentinel axillary lymph nodes of patients. However, the biological role mammaglobin completely unknown.We studied 128 fresh-frozen specimens means reverse transcriptase-polymerase chain reaction quantified their h-MAM mRNA expression. This was then correlated with histological nuclear grade, oestrogen progesterone receptor expression,...
Axillary node status after induction chemotherapy for locally advanced breast cancer has been shown on multivariate analysis to be an independent predictor of relapse. However, it postulated that responders with a clinically negative axilla could spared the burden lymphadenectomy, because most them will not show histological nodal invasion. P-glycoprotein expression in rescue mastectomy specimen finally identified as significant patient survival. We studied genes encoding multidrug...
The purpose of this study was to determine the accuracy magnetic resonance imaging (MRI) for evaluating depth myometrial invasion, potential sources pitfalls, and usefulness contrast-enhanced series. Eighty-five patients with a pathologic diagnosis endometrial carcinoma underwent preoperative MRI (plain contrast-enhanced). Grade presence junctional zone (JZ), fibromyomas, tumoral thickness were evaluated by two groups radiologists blinded results. Sensitivity, specificity, positive...