- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Breast Implant and Reconstruction
- HER2/EGFR in Cancer Research
- Cancer Risks and Factors
- Cancer survivorship and care
- Estrogen and related hormone effects
- Lung Cancer Treatments and Mutations
- Reproductive System and Pregnancy
- Palliative Care and End-of-Life Issues
- Advanced Radiotherapy Techniques
- Gestational Diabetes Research and Management
- BRCA gene mutations in cancer
- AI in cancer detection
- Cancer Genomics and Diagnostics
- Cancer-related cognitive impairment studies
- Radiation Dose and Imaging
- Advances in Oncology and Radiotherapy
- Advanced Breast Cancer Therapies
- Childhood Cancer Survivors' Quality of Life
- Occupational and environmental lung diseases
- Cancer Treatment and Pharmacology
- Patient Satisfaction in Healthcare
- Ectopic Pregnancy Diagnosis and Management
Maastricht University
2017-2024
Maastricht University Medical Centre
2017-2024
Mater Health Services
2021
Saudi Arabia Basic Industries (Netherlands)
2020
Michener Institute
2012
University of Toronto
2012
Studies showed that axillary lymph node dissection can be safely omitted in presence of positive sentinel node(s) breast cancer patients treated with conserving therapy. Since the outcome biopsy has no clinical consequence, value procedure itself is being questioned. The aim BOOG 2013–08 trial to investigate whether clinically negative a Dutch prospective non-inferiority randomized multicentre trial. Women pathologically confirmed T1–2 invasive undergoing therapy will for versus biopsy....
•In the BOOG 2013-08 trial, RT-protocol adherence was 98.5%.•Patients in a subanalysis received mean breast dose of ≥95% prescribed dose.•The majority patients limited incidental RT on nodal levels.•Incidental comparable between treatment arms.•The lymph node volumes were never unintentionally treated with V95%≥95%.
Abstract Background After breast cancer treatment, follow-up consists of physical examination and mammography for at least 5 years, to detect local regional recurrence. The risk recurrence may decrease after event-free time. This study aims determine the (LR) as a first event until years diagnosis, conditional on being 1, 2, 3 4 years. Methods From Netherlands Cancer Registry, all M0 cancers diagnosed between 2005 2008 were included. LR was calculated with Kaplan–Meier analysis, overall...
Abstract Purpose Omitting sentinel lymph node biopsy (SLNB) in breast cancer treatment results patients with unknown positive nodal status and potential risk for systemic undertreatment. This study aimed to investigate whether gene expression profiles (GEPs) can lower this cT1-2N0 ER+ HER2– treated BCT. Methods Patients were included if diagnosed between 2011 2017 cancer, BCT SLNB, whom GEP was applied. Adjuvant chemotherapy recommendations based on clinical (Dutch guideline of 2020 versus...
Abstract Purpose The prognostic stage group and Bioscore are novel staging systems for breast cancer patients. They provide a better view on five-year disease-specific survival (DSS) compared to the traditional system. Five-year follow-up might not be sufficient ER+HER2- tumors. This study determines five- 10-year recurrence-free (RFS) anatomic of 8 th AJCC TNM system, compares these Methods All newly diagnosed patients treated with primary surgery in 2005 were included from Netherlands...
Abstract Study question In women with threatened miscarriage, does progesterone supplementation increase the probability of live birth? Summary answer 400 mg nightly, from onset bleeding until 12 weeks, did not birth rates. What is known already Women a history miscarriage who present in early pregnancy may benefit use vaginal micronized mg. A recently published large randomised clinical trial indicated no overall for 16 although subgroup analysis and at least one previous might be...